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Clinical Institute for Children Healt... 1 Department of Pediatric Surgery Divis... 1 Department of Surgery S H Ho Urology ... 1 Department of Urology 2nd Faculty of ... 1 Department of Urology Clinico San Car... 1 Department of Urology University Hosp... 1 Department of Urology University of T... 1 Department of Urology Weill Cornell M... 1 Department of Urology and Comprehensi... 1 Division of Urology Department of Spe... 1 Division of Urology Rabin Medical Cen... 1 Institute for Urology and Reproductiv... 1 Institute of Molecular Theranostics S... 1 Karl Landsteiner Institute of Urology... 1 School of Medicine Brady Urological I... 1 Shemyakin Ovchinnikov Institute of Bi... 1
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Clinical Institute for Children Healt... 1 Department of Pediatric Surgery Divis... 1 Department of Surgery S H Ho Urology ... 1 Department of Urology 2nd Faculty of ... 1 Department of Urology Clinico San Car... 1 Department of Urology University Hosp... 1 Department of Urology University of T... 1 Department of Urology Weill Cornell M... 1 Department of Urology and Comprehensi... 1 Division of Urology Department of Spe... 1 Division of Urology Rabin Medical Cen... 1 Institute for Urology and Reproductiv... 1 Institute of Molecular Theranostics S... 1 Karl Landsteiner Institute of Urology... 1 School of Medicine Brady Urological I... 1 Shemyakin Ovchinnikov Institute of Bi... 1
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- Bazarkin, Andrey
- Morozov, Andrey
- Androsov, Alexander
- Fajkovic, Harun
- Rivas, Juan Gomez
- Singla, Nirmish
- Koroleva, Svetlana
- Teoh, Jeremy Yuen-Chun
- Zvyagin, Andrei V
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Shariat, Shahrokh François
Autor Shariat, Shahrokh François Department of Urology and Comprehensive Cancer Center, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria Karl Landsteiner Institute of Urology and Andrology, Vienna, Austria Department of Urology, Weill Cornell Medical College, New York, NY, USA Department of Urology, University of Texas Southwestern, Dallas, TX, USA Department of Urology, Second Faculty of Medicine, Charles University, Prague, Czech Republic Division of Urology, Department of Special Surgery, Jordan University Hospital, The University of Jordan, Amman, Jordan
PURPOSE OF REVIEW: The aim of the systematic review is to assess AI's capabilities in the genetics of prostate cancer (PCa) and bladder cancer (BCa) to evaluate target groups for such analysis as well as to assess its prospects in daily practice. RECENT FINDINGS: In total, our analysis included 27 articles: 10 articles have reported on PCa and 17 on BCa, respectively. The AI algorithms added clinical value and demonstrated promising results in several fields, including cancer detection, assessment of cancer development risk, risk stratification in terms of survival and relapse, and prediction of response to a specific therapy. Besides clinical applications, genetic analysis aided by the AI shed light on the basic urologic cancer biology. We believe, our results of the AI application to the analysis of PCa, BCa data sets will help to identify new targets for urological cancer therapy. The integration of AI in genomic research for screening and clinical applications will evolve with time to help personalizing chemotherapy, prediction of survival and relapse, aid treatment strategies such as reducing frequency of diagnostic cystoscopies, and clinical decision support, e.g., by predicting immunotherapy response. These factors will ultimately lead to personalized and precision medicine thereby improving patient outcomes.
- MeSH
- biologické markery MeSH
- lidé MeSH
- lokální recidiva nádoru genetika MeSH
- nádory močového měchýře * diagnóza genetika terapie MeSH
- prostata * MeSH
- recidiva MeSH
- umělá inteligence MeSH
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- lidé MeSH
- mužské pohlaví MeSH
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- časopisecké články MeSH
- přehledy MeSH
- systematický přehled MeSH
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