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Autor
Abbasi, Siddique A 1 Adams, Kirkwood F 1 Anand, Inder 1 Arias-Mendoza, Alexandra 1 Biering-Sørensen, Tor 1 Bonderman, Diana 1 Böhm, Michael 1 Cleland, John G F 1 Corbalan, Ramon 1 Crespo-Leiro, Maria G 1 Dahlström, Ulf 1 Diaz, Rafael 1 Echeverria, Luis E 1 Fang, James C 1 Felker, G Michael 1 Filippatos, Gerasimos 1 Fonseca, Cândida 1 Goncalvesova, Eva 1 Goudev, Assen R 1 Honarpour, Narimon 1
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Pracoviště
AZ Sint Lucas Ghent Belgium 1 Cardiology ASST Spedali Civili Depart... 1 Commenius University Bratislava Slovakia 1 Complexo Hospitalario Universitario A... 1 Dokuz Eylul University Izmir Turkey 1 Estudios Clínicos Latino América Rosa... 1 From the Section of Cardiology San Fr... 1 Fundación Cardiovascular de Colombia ... 1 Hospital S Francisco Xavier Centro Ho... 1 Institute of Cardiology Kyiv Ukraine 1 Instituto Nacional de Cardiología Mex... 1 Instituto do Coração Hospital das Clí... 1 Libin Cardiovascular Institute and Cu... 1 Medical University of Vienna Vienna 1 Middlemore Hospital Otahuhu Auckland ... 1 National and Kapodistrian University ... 1 Pontificia Universidad Católica de Ch... 1 Saarland University Universitätsklini... 1 Saitama Citizens Medical Center Saita... 1 St John of God Hospital Budapest Hungary 1
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Autor
Abbasi, Siddique A 1 Adams, Kirkwood F 1 Anand, Inder 1 Arias-Mendoza, Alexandra 1 Biering-Sørensen, Tor 1 Bonderman, Diana 1 Böhm, Michael 1 Cleland, John G F 1 Corbalan, Ramon 1 Crespo-Leiro, Maria G 1 Dahlström, Ulf 1 Diaz, Rafael 1 Echeverria, Luis E 1 Fang, James C 1 Felker, G Michael 1 Filippatos, Gerasimos 1 Fonseca, Cândida 1 Goncalvesova, Eva 1 Goudev, Assen R 1 Honarpour, Narimon 1
- Organizace
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Pracoviště
AZ Sint Lucas Ghent Belgium 1 Cardiology ASST Spedali Civili Depart... 1 Commenius University Bratislava Slovakia 1 Complexo Hospitalario Universitario A... 1 Dokuz Eylul University Izmir Turkey 1 Estudios Clínicos Latino América Rosa... 1 From the Section of Cardiology San Fr... 1 Fundación Cardiovascular de Colombia ... 1 Hospital S Francisco Xavier Centro Ho... 1 Institute of Cardiology Kyiv Ukraine 1 Instituto Nacional de Cardiología Mex... 1 Instituto do Coração Hospital das Clí... 1 Libin Cardiovascular Institute and Cu... 1 Medical University of Vienna Vienna 1 Middlemore Hospital Otahuhu Auckland ... 1 National and Kapodistrian University ... 1 Pontificia Universidad Católica de Ch... 1 Saarland University Universitätsklini... 1 Saitama Citizens Medical Center Saita... 1 St John of God Hospital Budapest Hungary 1
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Teerlink, John R
Autor Teerlink, John R From the Section of Cardiology, San Francisco Veterans Affairs Medical Center and School of Medicine, University of California, San Francisco, San Francisco (J.R.T.), Amgen, Thousand Oaks (L.S., J.C.L., N.H., S.A.A., C.E.K.), and Cytokinetics, South San Francisco (F.I.M.) - all in California Estudios Clínicos Latino América, Rosario, Argentina (R.D.) the Division of Cardiology, Duke University School of Medicine and Duke Clinical Research Institute, Durham (G.M.F.), and the University of North Carolina, Chapel Hill (K.F.A.) - both in North Carolina the British Heart Foundation Cardiovascular Research Centre (J.J.V.M.) and the Robertson Centre for Biostatistics and Clinical Trials, Institute of Health and Wellbeing (J.G.F.C.), University of Glasgow, Glasgow, and the National Heart and Lung Institute, Imperial College, London (J.G.F.C.) - both in the United Kingdom Cardiology, ASST Spedali Civili, Department of Medical and Surgical Specialties, Radiologic Sciences, and Public Health, University of Brescia, Brescia, Italy (M.M.) the Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston (S.D.S.) the University of Minnesota, Minneapolis (I.A.) Instituto Nacional de Cardiología, Mexico City (A.A.-M.) the Department of Cardiology, Herlev and Gentofte Hospital, and the Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen (T.B.-S.) Saarland University, Universitätsklinikum des Saarlandes, Homburg, Germany (M.B.) Medical University of Vienna, Vienna (D.B.) Pontificia Universidad Católica de Chile, Santiago (R.C.) Complexo Hospitalario Universitario A Coruña, Centro de Investigación Biomédica en Red, Enfermedades Cardiovasculares, Instituto de Investigación Biomédica de A Coruña, Universidade da Coruña, A Coruña, Spain (M.G.C.-L.) the Departments of Cardiology and Health, Medicine and Caring Sciences, Linkoping University, Linkoping, Sweden (U.D.) Fundación Cardiovascular de Colombia, Floridablanca, Colombia (L.E.E.) University of Utah, Salt Lake City (J.C.F.) National and Kapodistrian University of Athens, Attikon University Hospital, Athens (G.F.) Hospital S. Francisco Xavier, Centro Hospitalar Lisboa Ocidental, NOVA Medical School, Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Lisbon, Portugal (C.F.) Commenius University, Bratislava, Slovakia (E.G.) the Department of Cardiology, Queen Giovanna University Hospital and Medical University, Sofia, Bulgaria (A.R.G.) Libin Cardiovascular Institute and Cumming School of Medicine, University of Calgary, Calgary, AB (J.G.H.), and Montreal Heart Institute and Université de Montréal, Montreal (E.O.) - both in Canada the Heart and Vascular Institute, Henry Ford Hospital, Detroit (D.E.L.) the National Clinical Research Center for Cardiovascular Diseases, National Health Commission Key Laboratory of Clinical Research for Cardiovascular Medications, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing (J.L.) Middlemore Hospital, Otahuhu, Auckland, New Zealand (M.L.) St. Vincent's Hospital Sydney, Darlinghurst, NSW, Australia (P.M.) University Clinic of Lomonosov, Moscow State University, Moscow (V.M.) Saitama Citizens Medical Center, Saitama, Japan (S.M.) Institute of Cardiology, Kyiv, Ukraine (A.P.) Wroclaw Medical University, Wroclaw, Poland (P.P.) Instituto do Coração, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Faculdade de Medicina, Universidade de São Paulo, São Paulo (F.J.A.R.) Vilnius University, Vilnius, Lithuania (P.S.) the University of Cape Town, Cape Town, South Africa (K.S.) the Internal Cardiology Department, St. Ann Hospital and Masaryk University Brno, Brno, Czech Republic (J.S.) the Department of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland (T.M.S.) St. John of God Hospital, Budapest, Hungary (J.T.) AZ Sint-Lucas, Ghent, Belgium (H.V.) the University of Medicine and Pharmacy Carol Davila, University and Emergency Hospital, Bucharest, Romania (D.V.) the University of Groningen, Groningen, the Netherlands (A.A.V.) Dokuz Eylul University, Izmir, Turkey (M.B.Y.) and Université de Lorraine, INSERM Investigation Network Initiative Cardiovascular and Renal Clinical Trialists, Centre Hospitalier Régional Universitaire de Nancy, Nancy (F.Z.), and Servier, Suresnes (C.V.) - both in France
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Diaz, Rafael
Autor Diaz, Rafael From the Section of Cardiology, San Francisco Veterans Affairs Medical Center and School of Medicine, University of California, San Francisco, San Francisco (J.R.T.), Amgen, Thousand Oaks (L.S., J.C.L., N.H., S.A.A., C.E.K.), and Cytokinetics, South San Francisco (F.I.M.) - all in California Estudios Clínicos Latino América, Rosario, Argentina (R.D.) the Division of Cardiology, Duke University School of Medicine and Duke Clinical Research Institute, Durham (G.M.F.), and the University of North Carolina, Chapel Hill (K.F.A.) - both in North Carolina the British Heart Foundation Cardiovascular Research Centre (J.J.V.M.) and the Robertson Centre for Biostatistics and Clinical Trials, Institute of Health and Wellbeing (J.G.F.C.), University of Glasgow, Glasgow, and the National Heart and Lung Institute, Imperial College, London (J.G.F.C.) - both in the United Kingdom Cardiology, ASST Spedali Civili, Department of Medical and Surgical Specialties, Radiologic Sciences, and Public Health, University of Brescia, Brescia, Italy (M.M.) the Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston (S.D.S.) the University of Minnesota, Minneapolis (I.A.) Instituto Nacional de Cardiología, Mexico City (A.A.-M.) the Department of Cardiology, Herlev and Gentofte Hospital, and the Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen (T.B.-S.) Saarland University, Universitätsklinikum des Saarlandes, Homburg, Germany (M.B.) Medical University of Vienna, Vienna (D.B.) Pontificia Universidad Católica de Chile, Santiago (R.C.) Complexo Hospitalario Universitario A Coruña, Centro de Investigación Biomédica en Red, Enfermedades Cardiovasculares, Instituto de Investigación Biomédica de A Coruña, Universidade da Coruña, A Coruña, Spain (M.G.C.-L.) the Departments of Cardiology and Health, Medicine and Caring Sciences, Linkoping University, Linkoping, Sweden (U.D.) Fundación Cardiovascular de Colombia, Floridablanca, Colombia (L.E.E.) University of Utah, Salt Lake City (J.C.F.) National and Kapodistrian University of Athens, Attikon University Hospital, Athens (G.F.) Hospital S. Francisco Xavier, Centro Hospitalar Lisboa Ocidental, NOVA Medical School, Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Lisbon, Portugal (C.F.) Commenius University, Bratislava, Slovakia (E.G.) the Department of Cardiology, Queen Giovanna University Hospital and Medical University, Sofia, Bulgaria (A.R.G.) Libin Cardiovascular Institute and Cumming School of Medicine, University of Calgary, Calgary, AB (J.G.H.), and Montreal Heart Institute and Université de Montréal, Montreal (E.O.) - both in Canada the Heart and Vascular Institute, Henry Ford Hospital, Detroit (D.E.L.) the National Clinical Research Center for Cardiovascular Diseases, National Health Commission Key Laboratory of Clinical Research for Cardiovascular Medications, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing (J.L.) Middlemore Hospital, Otahuhu, Auckland, New Zealand (M.L.) St. Vincent's Hospital Sydney, Darlinghurst, NSW, Australia (P.M.) University Clinic of Lomonosov, Moscow State University, Moscow (V.M.) Saitama Citizens Medical Center, Saitama, Japan (S.M.) Institute of Cardiology, Kyiv, Ukraine (A.P.) Wroclaw Medical University, Wroclaw, Poland (P.P.) Instituto do Coração, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Faculdade de Medicina, Universidade de São Paulo, São Paulo (F.J.A.R.) Vilnius University, Vilnius, Lithuania (P.S.) the University of Cape Town, Cape Town, South Africa (K.S.) the Internal Cardiology Department, St. Ann Hospital and Masaryk University Brno, Brno, Czech Republic (J.S.) the Department of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland (T.M.S.) St. John of God Hospital, Budapest, Hungary (J.T.) AZ Sint-Lucas, Ghent, Belgium (H.V.) the University of Medicine and Pharmacy Carol Davila, University and Emergency Hospital, Bucharest, Romania (D.V.) the University of Groningen, Groningen, the Netherlands (A.A.V.) Dokuz Eylul University, Izmir, Turkey (M.B.Y.) and Université de Lorraine, INSERM Investigation Network Initiative Cardiovascular and Renal Clinical Trialists, Centre Hospitalier Régional Universitaire de Nancy, Nancy (F.Z.), and Servier, Suresnes (C.V.) - both in France
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Felker, G Michael
Autor Felker, G Michael From the Section of Cardiology, San Francisco Veterans Affairs Medical Center and School of Medicine, University of California, San Francisco, San Francisco (J.R.T.), Amgen, Thousand Oaks (L.S., J.C.L., N.H., S.A.A., C.E.K.), and Cytokinetics, South San Francisco (F.I.M.) - all in California Estudios Clínicos Latino América, Rosario, Argentina (R.D.) the Division of Cardiology, Duke University School of Medicine and Duke Clinical Research Institute, Durham (G.M.F.), and the University of North Carolina, Chapel Hill (K.F.A.) - both in North Carolina the British Heart Foundation Cardiovascular Research Centre (J.J.V.M.) and the Robertson Centre for Biostatistics and Clinical Trials, Institute of Health and Wellbeing (J.G.F.C.), University of Glasgow, Glasgow, and the National Heart and Lung Institute, Imperial College, London (J.G.F.C.) - both in the United Kingdom Cardiology, ASST Spedali Civili, Department of Medical and Surgical Specialties, Radiologic Sciences, and Public Health, University of Brescia, Brescia, Italy (M.M.) the Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston (S.D.S.) the University of Minnesota, Minneapolis (I.A.) Instituto Nacional de Cardiología, Mexico City (A.A.-M.) the Department of Cardiology, Herlev and Gentofte Hospital, and the Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen (T.B.-S.) Saarland University, Universitätsklinikum des Saarlandes, Homburg, Germany (M.B.) Medical University of Vienna, Vienna (D.B.) Pontificia Universidad Católica de Chile, Santiago (R.C.) Complexo Hospitalario Universitario A Coruña, Centro de Investigación Biomédica en Red, Enfermedades Cardiovasculares, Instituto de Investigación Biomédica de A Coruña, Universidade da Coruña, A Coruña, Spain (M.G.C.-L.) the Departments of Cardiology and Health, Medicine and Caring Sciences, Linkoping University, Linkoping, Sweden (U.D.) Fundación Cardiovascular de Colombia, Floridablanca, Colombia (L.E.E.) University of Utah, Salt Lake City (J.C.F.) National and Kapodistrian University of Athens, Attikon University Hospital, Athens (G.F.) Hospital S. Francisco Xavier, Centro Hospitalar Lisboa Ocidental, NOVA Medical School, Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Lisbon, Portugal (C.F.) Commenius University, Bratislava, Slovakia (E.G.) the Department of Cardiology, Queen Giovanna University Hospital and Medical University, Sofia, Bulgaria (A.R.G.) Libin Cardiovascular Institute and Cumming School of Medicine, University of Calgary, Calgary, AB (J.G.H.), and Montreal Heart Institute and Université de Montréal, Montreal (E.O.) - both in Canada the Heart and Vascular Institute, Henry Ford Hospital, Detroit (D.E.L.) the National Clinical Research Center for Cardiovascular Diseases, National Health Commission Key Laboratory of Clinical Research for Cardiovascular Medications, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing (J.L.) Middlemore Hospital, Otahuhu, Auckland, New Zealand (M.L.) St. Vincent's Hospital Sydney, Darlinghurst, NSW, Australia (P.M.) University Clinic of Lomonosov, Moscow State University, Moscow (V.M.) Saitama Citizens Medical Center, Saitama, Japan (S.M.) Institute of Cardiology, Kyiv, Ukraine (A.P.) Wroclaw Medical University, Wroclaw, Poland (P.P.) Instituto do Coração, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Faculdade de Medicina, Universidade de São Paulo, São Paulo (F.J.A.R.) Vilnius University, Vilnius, Lithuania (P.S.) the University of Cape Town, Cape Town, South Africa (K.S.) the Internal Cardiology Department, St. Ann Hospital and Masaryk University Brno, Brno, Czech Republic (J.S.) the Department of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland (T.M.S.) St. John of God Hospital, Budapest, Hungary (J.T.) AZ Sint-Lucas, Ghent, Belgium (H.V.) the University of Medicine and Pharmacy Carol Davila, University and Emergency Hospital, Bucharest, Romania (D.V.) the University of Groningen, Groningen, the Netherlands (A.A.V.) Dokuz Eylul University, Izmir, Turkey (M.B.Y.) and Université de Lorraine, INSERM Investigation Network Initiative Cardiovascular and Renal Clinical Trialists, Centre Hospitalier Régional Universitaire de Nancy, Nancy (F.Z.), and Servier, Suresnes (C.V.) - both in France
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McMurray, John J V
Autor McMurray, John J V From the Section of Cardiology, San Francisco Veterans Affairs Medical Center and School of Medicine, University of California, San Francisco, San Francisco (J.R.T.), Amgen, Thousand Oaks (L.S., J.C.L., N.H., S.A.A., C.E.K.), and Cytokinetics, South San Francisco (F.I.M.) - all in California Estudios Clínicos Latino América, Rosario, Argentina (R.D.) the Division of Cardiology, Duke University School of Medicine and Duke Clinical Research Institute, Durham (G.M.F.), and the University of North Carolina, Chapel Hill (K.F.A.) - both in North Carolina the British Heart Foundation Cardiovascular Research Centre (J.J.V.M.) and the Robertson Centre for Biostatistics and Clinical Trials, Institute of Health and Wellbeing (J.G.F.C.), University of Glasgow, Glasgow, and the National Heart and Lung Institute, Imperial College, London (J.G.F.C.) - both in the United Kingdom Cardiology, ASST Spedali Civili, Department of Medical and Surgical Specialties, Radiologic Sciences, and Public Health, University of Brescia, Brescia, Italy (M.M.) the Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston (S.D.S.) the University of Minnesota, Minneapolis (I.A.) Instituto Nacional de Cardiología, Mexico City (A.A.-M.) the Department of Cardiology, Herlev and Gentofte Hospital, and the Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen (T.B.-S.) Saarland University, Universitätsklinikum des Saarlandes, Homburg, Germany (M.B.) Medical University of Vienna, Vienna (D.B.) Pontificia Universidad Católica de Chile, Santiago (R.C.) Complexo Hospitalario Universitario A Coruña, Centro de Investigación Biomédica en Red, Enfermedades Cardiovasculares, Instituto de Investigación Biomédica de A Coruña, Universidade da Coruña, A Coruña, Spain (M.G.C.-L.) the Departments of Cardiology and Health, Medicine and Caring Sciences, Linkoping University, Linkoping, Sweden (U.D.) Fundación Cardiovascular de Colombia, Floridablanca, Colombia (L.E.E.) University of Utah, Salt Lake City (J.C.F.) National and Kapodistrian University of Athens, Attikon University Hospital, Athens (G.F.) Hospital S. Francisco Xavier, Centro Hospitalar Lisboa Ocidental, NOVA Medical School, Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Lisbon, Portugal (C.F.) Commenius University, Bratislava, Slovakia (E.G.) the Department of Cardiology, Queen Giovanna University Hospital and Medical University, Sofia, Bulgaria (A.R.G.) Libin Cardiovascular Institute and Cumming School of Medicine, University of Calgary, Calgary, AB (J.G.H.), and Montreal Heart Institute and Université de Montréal, Montreal (E.O.) - both in Canada the Heart and Vascular Institute, Henry Ford Hospital, Detroit (D.E.L.) the National Clinical Research Center for Cardiovascular Diseases, National Health Commission Key Laboratory of Clinical Research for Cardiovascular Medications, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing (J.L.) Middlemore Hospital, Otahuhu, Auckland, New Zealand (M.L.) St. Vincent's Hospital Sydney, Darlinghurst, NSW, Australia (P.M.) University Clinic of Lomonosov, Moscow State University, Moscow (V.M.) Saitama Citizens Medical Center, Saitama, Japan (S.M.) Institute of Cardiology, Kyiv, Ukraine (A.P.) Wroclaw Medical University, Wroclaw, Poland (P.P.) Instituto do Coração, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Faculdade de Medicina, Universidade de São Paulo, São Paulo (F.J.A.R.) Vilnius University, Vilnius, Lithuania (P.S.) the University of Cape Town, Cape Town, South Africa (K.S.) the Internal Cardiology Department, St. Ann Hospital and Masaryk University Brno, Brno, Czech Republic (J.S.) the Department of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland (T.M.S.) St. John of God Hospital, Budapest, Hungary (J.T.) AZ Sint-Lucas, Ghent, Belgium (H.V.) the University of Medicine and Pharmacy Carol Davila, University and Emergency Hospital, Bucharest, Romania (D.V.) the University of Groningen, Groningen, the Netherlands (A.A.V.) Dokuz Eylul University, Izmir, Turkey (M.B.Y.) and Université de Lorraine, INSERM Investigation Network Initiative Cardiovascular and Renal Clinical Trialists, Centre Hospitalier Régional Universitaire de Nancy, Nancy (F.Z.), and Servier, Suresnes (C.V.) - both in France
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Metra, Marco
Autor Metra, Marco From the Section of Cardiology, San Francisco Veterans Affairs Medical Center and School of Medicine, University of California, San Francisco, San Francisco (J.R.T.), Amgen, Thousand Oaks (L.S., J.C.L., N.H., S.A.A., C.E.K.), and Cytokinetics, South San Francisco (F.I.M.) - all in California Estudios Clínicos Latino América, Rosario, Argentina (R.D.) the Division of Cardiology, Duke University School of Medicine and Duke Clinical Research Institute, Durham (G.M.F.), and the University of North Carolina, Chapel Hill (K.F.A.) - both in North Carolina the British Heart Foundation Cardiovascular Research Centre (J.J.V.M.) and the Robertson Centre for Biostatistics and Clinical Trials, Institute of Health and Wellbeing (J.G.F.C.), University of Glasgow, Glasgow, and the National Heart and Lung Institute, Imperial College, London (J.G.F.C.) - both in the United Kingdom Cardiology, ASST Spedali Civili, Department of Medical and Surgical Specialties, Radiologic Sciences, and Public Health, University of Brescia, Brescia, Italy (M.M.) the Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston (S.D.S.) the University of Minnesota, Minneapolis (I.A.) Instituto Nacional de Cardiología, Mexico City (A.A.-M.) the Department of Cardiology, Herlev and Gentofte Hospital, and the Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen (T.B.-S.) Saarland University, Universitätsklinikum des Saarlandes, Homburg, Germany (M.B.) Medical University of Vienna, Vienna (D.B.) Pontificia Universidad Católica de Chile, Santiago (R.C.) Complexo Hospitalario Universitario A Coruña, Centro de Investigación Biomédica en Red, Enfermedades Cardiovasculares, Instituto de Investigación Biomédica de A Coruña, Universidade da Coruña, A Coruña, Spain (M.G.C.-L.) the Departments of Cardiology and Health, Medicine and Caring Sciences, Linkoping University, Linkoping, Sweden (U.D.) Fundación Cardiovascular de Colombia, Floridablanca, Colombia (L.E.E.) University of Utah, Salt Lake City (J.C.F.) National and Kapodistrian University of Athens, Attikon University Hospital, Athens (G.F.) Hospital S. Francisco Xavier, Centro Hospitalar Lisboa Ocidental, NOVA Medical School, Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Lisbon, Portugal (C.F.) Commenius University, Bratislava, Slovakia (E.G.) the Department of Cardiology, Queen Giovanna University Hospital and Medical University, Sofia, Bulgaria (A.R.G.) Libin Cardiovascular Institute and Cumming School of Medicine, University of Calgary, Calgary, AB (J.G.H.), and Montreal Heart Institute and Université de Montréal, Montreal (E.O.) - both in Canada the Heart and Vascular Institute, Henry Ford Hospital, Detroit (D.E.L.) the National Clinical Research Center for Cardiovascular Diseases, National Health Commission Key Laboratory of Clinical Research for Cardiovascular Medications, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing (J.L.) Middlemore Hospital, Otahuhu, Auckland, New Zealand (M.L.) St. Vincent's Hospital Sydney, Darlinghurst, NSW, Australia (P.M.) University Clinic of Lomonosov, Moscow State University, Moscow (V.M.) Saitama Citizens Medical Center, Saitama, Japan (S.M.) Institute of Cardiology, Kyiv, Ukraine (A.P.) Wroclaw Medical University, Wroclaw, Poland (P.P.) Instituto do Coração, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Faculdade de Medicina, Universidade de São Paulo, São Paulo (F.J.A.R.) Vilnius University, Vilnius, Lithuania (P.S.) the University of Cape Town, Cape Town, South Africa (K.S.) the Internal Cardiology Department, St. Ann Hospital and Masaryk University Brno, Brno, Czech Republic (J.S.) the Department of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland (T.M.S.) St. John of God Hospital, Budapest, Hungary (J.T.) AZ Sint-Lucas, Ghent, Belgium (H.V.) the University of Medicine and Pharmacy Carol Davila, University and Emergency Hospital, Bucharest, Romania (D.V.) the University of Groningen, Groningen, the Netherlands (A.A.V.) Dokuz Eylul University, Izmir, Turkey (M.B.Y.) and Université de Lorraine, INSERM Investigation Network Initiative Cardiovascular and Renal Clinical Trialists, Centre Hospitalier Régional Universitaire de Nancy, Nancy (F.Z.), and Servier, Suresnes (C.V.) - both in France
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Solomon, Scott D
Autor Solomon, Scott D From the Section of Cardiology, San Francisco Veterans Affairs Medical Center and School of Medicine, University of California, San Francisco, San Francisco (J.R.T.), Amgen, Thousand Oaks (L.S., J.C.L., N.H., S.A.A., C.E.K.), and Cytokinetics, South San Francisco (F.I.M.) - all in California Estudios Clínicos Latino América, Rosario, Argentina (R.D.) the Division of Cardiology, Duke University School of Medicine and Duke Clinical Research Institute, Durham (G.M.F.), and the University of North Carolina, Chapel Hill (K.F.A.) - both in North Carolina the British Heart Foundation Cardiovascular Research Centre (J.J.V.M.) and the Robertson Centre for Biostatistics and Clinical Trials, Institute of Health and Wellbeing (J.G.F.C.), University of Glasgow, Glasgow, and the National Heart and Lung Institute, Imperial College, London (J.G.F.C.) - both in the United Kingdom Cardiology, ASST Spedali Civili, Department of Medical and Surgical Specialties, Radiologic Sciences, and Public Health, University of Brescia, Brescia, Italy (M.M.) the Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston (S.D.S.) the University of Minnesota, Minneapolis (I.A.) Instituto Nacional de Cardiología, Mexico City (A.A.-M.) the Department of Cardiology, Herlev and Gentofte Hospital, and the Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen (T.B.-S.) Saarland University, Universitätsklinikum des Saarlandes, Homburg, Germany (M.B.) Medical University of Vienna, Vienna (D.B.) Pontificia Universidad Católica de Chile, Santiago (R.C.) Complexo Hospitalario Universitario A Coruña, Centro de Investigación Biomédica en Red, Enfermedades Cardiovasculares, Instituto de Investigación Biomédica de A Coruña, Universidade da Coruña, A Coruña, Spain (M.G.C.-L.) the Departments of Cardiology and Health, Medicine and Caring Sciences, Linkoping University, Linkoping, Sweden (U.D.) Fundación Cardiovascular de Colombia, Floridablanca, Colombia (L.E.E.) University of Utah, Salt Lake City (J.C.F.) National and Kapodistrian University of Athens, Attikon University Hospital, Athens (G.F.) Hospital S. Francisco Xavier, Centro Hospitalar Lisboa Ocidental, NOVA Medical School, Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Lisbon, Portugal (C.F.) Commenius University, Bratislava, Slovakia (E.G.) the Department of Cardiology, Queen Giovanna University Hospital and Medical University, Sofia, Bulgaria (A.R.G.) Libin Cardiovascular Institute and Cumming School of Medicine, University of Calgary, Calgary, AB (J.G.H.), and Montreal Heart Institute and Université de Montréal, Montreal (E.O.) - both in Canada the Heart and Vascular Institute, Henry Ford Hospital, Detroit (D.E.L.) the National Clinical Research Center for Cardiovascular Diseases, National Health Commission Key Laboratory of Clinical Research for Cardiovascular Medications, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing (J.L.) Middlemore Hospital, Otahuhu, Auckland, New Zealand (M.L.) St. Vincent's Hospital Sydney, Darlinghurst, NSW, Australia (P.M.) University Clinic of Lomonosov, Moscow State University, Moscow (V.M.) Saitama Citizens Medical Center, Saitama, Japan (S.M.) Institute of Cardiology, Kyiv, Ukraine (A.P.) Wroclaw Medical University, Wroclaw, Poland (P.P.) Instituto do Coração, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Faculdade de Medicina, Universidade de São Paulo, São Paulo (F.J.A.R.) Vilnius University, Vilnius, Lithuania (P.S.) the University of Cape Town, Cape Town, South Africa (K.S.) the Internal Cardiology Department, St. Ann Hospital and Masaryk University Brno, Brno, Czech Republic (J.S.) the Department of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland (T.M.S.) St. John of God Hospital, Budapest, Hungary (J.T.) AZ Sint-Lucas, Ghent, Belgium (H.V.) the University of Medicine and Pharmacy Carol Davila, University and Emergency Hospital, Bucharest, Romania (D.V.) the University of Groningen, Groningen, the Netherlands (A.A.V.) Dokuz Eylul University, Izmir, Turkey (M.B.Y.) and Université de Lorraine, INSERM Investigation Network Initiative Cardiovascular and Renal Clinical Trialists, Centre Hospitalier Régional Universitaire de Nancy, Nancy (F.Z.), and Servier, Suresnes (C.V.) - both in France
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Adams, Kirkwood F
Autor Adams, Kirkwood F From the Section of Cardiology, San Francisco Veterans Affairs Medical Center and School of Medicine, University of California, San Francisco, San Francisco (J.R.T.), Amgen, Thousand Oaks (L.S., J.C.L., N.H., S.A.A., C.E.K.), and Cytokinetics, South San Francisco (F.I.M.) - all in California Estudios Clínicos Latino América, Rosario, Argentina (R.D.) the Division of Cardiology, Duke University School of Medicine and Duke Clinical Research Institute, Durham (G.M.F.), and the University of North Carolina, Chapel Hill (K.F.A.) - both in North Carolina the British Heart Foundation Cardiovascular Research Centre (J.J.V.M.) and the Robertson Centre for Biostatistics and Clinical Trials, Institute of Health and Wellbeing (J.G.F.C.), University of Glasgow, Glasgow, and the National Heart and Lung Institute, Imperial College, London (J.G.F.C.) - both in the United Kingdom Cardiology, ASST Spedali Civili, Department of Medical and Surgical Specialties, Radiologic Sciences, and Public Health, University of Brescia, Brescia, Italy (M.M.) the Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston (S.D.S.) the University of Minnesota, Minneapolis (I.A.) Instituto Nacional de Cardiología, Mexico City (A.A.-M.) the Department of Cardiology, Herlev and Gentofte Hospital, and the Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen (T.B.-S.) Saarland University, Universitätsklinikum des Saarlandes, Homburg, Germany (M.B.) Medical University of Vienna, Vienna (D.B.) Pontificia Universidad Católica de Chile, Santiago (R.C.) Complexo Hospitalario Universitario A Coruña, Centro de Investigación Biomédica en Red, Enfermedades Cardiovasculares, Instituto de Investigación Biomédica de A Coruña, Universidade da Coruña, A Coruña, Spain (M.G.C.-L.) the Departments of Cardiology and Health, Medicine and Caring Sciences, Linkoping University, Linkoping, Sweden (U.D.) Fundación Cardiovascular de Colombia, Floridablanca, Colombia (L.E.E.) University of Utah, Salt Lake City (J.C.F.) National and Kapodistrian University of Athens, Attikon University Hospital, Athens (G.F.) Hospital S. Francisco Xavier, Centro Hospitalar Lisboa Ocidental, NOVA Medical School, Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Lisbon, Portugal (C.F.) Commenius University, Bratislava, Slovakia (E.G.) the Department of Cardiology, Queen Giovanna University Hospital and Medical University, Sofia, Bulgaria (A.R.G.) Libin Cardiovascular Institute and Cumming School of Medicine, University of Calgary, Calgary, AB (J.G.H.), and Montreal Heart Institute and Université de Montréal, Montreal (E.O.) - both in Canada the Heart and Vascular Institute, Henry Ford Hospital, Detroit (D.E.L.) the National Clinical Research Center for Cardiovascular Diseases, National Health Commission Key Laboratory of Clinical Research for Cardiovascular Medications, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing (J.L.) Middlemore Hospital, Otahuhu, Auckland, New Zealand (M.L.) St. Vincent's Hospital Sydney, Darlinghurst, NSW, Australia (P.M.) University Clinic of Lomonosov, Moscow State University, Moscow (V.M.) Saitama Citizens Medical Center, Saitama, Japan (S.M.) Institute of Cardiology, Kyiv, Ukraine (A.P.) Wroclaw Medical University, Wroclaw, Poland (P.P.) Instituto do Coração, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Faculdade de Medicina, Universidade de São Paulo, São Paulo (F.J.A.R.) Vilnius University, Vilnius, Lithuania (P.S.) the University of Cape Town, Cape Town, South Africa (K.S.) the Internal Cardiology Department, St. Ann Hospital and Masaryk University Brno, Brno, Czech Republic (J.S.) the Department of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland (T.M.S.) St. John of God Hospital, Budapest, Hungary (J.T.) AZ Sint-Lucas, Ghent, Belgium (H.V.) the University of Medicine and Pharmacy Carol Davila, University and Emergency Hospital, Bucharest, Romania (D.V.) the University of Groningen, Groningen, the Netherlands (A.A.V.) Dokuz Eylul University, Izmir, Turkey (M.B.Y.) and Université de Lorraine, INSERM Investigation Network Initiative Cardiovascular and Renal Clinical Trialists, Centre Hospitalier Régional Universitaire de Nancy, Nancy (F.Z.), and Servier, Suresnes (C.V.) - both in France
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Anand, Inder
Autor Anand, Inder From the Section of Cardiology, San Francisco Veterans Affairs Medical Center and School of Medicine, University of California, San Francisco, San Francisco (J.R.T.), Amgen, Thousand Oaks (L.S., J.C.L., N.H., S.A.A., C.E.K.), and Cytokinetics, South San Francisco (F.I.M.) - all in California Estudios Clínicos Latino América, Rosario, Argentina (R.D.) the Division of Cardiology, Duke University School of Medicine and Duke Clinical Research Institute, Durham (G.M.F.), and the University of North Carolina, Chapel Hill (K.F.A.) - both in North Carolina the British Heart Foundation Cardiovascular Research Centre (J.J.V.M.) and the Robertson Centre for Biostatistics and Clinical Trials, Institute of Health and Wellbeing (J.G.F.C.), University of Glasgow, Glasgow, and the National Heart and Lung Institute, Imperial College, London (J.G.F.C.) - both in the United Kingdom Cardiology, ASST Spedali Civili, Department of Medical and Surgical Specialties, Radiologic Sciences, and Public Health, University of Brescia, Brescia, Italy (M.M.) the Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston (S.D.S.) the University of Minnesota, Minneapolis (I.A.) Instituto Nacional de Cardiología, Mexico City (A.A.-M.) the Department of Cardiology, Herlev and Gentofte Hospital, and the Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen (T.B.-S.) Saarland University, Universitätsklinikum des Saarlandes, Homburg, Germany (M.B.) Medical University of Vienna, Vienna (D.B.) Pontificia Universidad Católica de Chile, Santiago (R.C.) Complexo Hospitalario Universitario A Coruña, Centro de Investigación Biomédica en Red, Enfermedades Cardiovasculares, Instituto de Investigación Biomédica de A Coruña, Universidade da Coruña, A Coruña, Spain (M.G.C.-L.) the Departments of Cardiology and Health, Medicine and Caring Sciences, Linkoping University, Linkoping, Sweden (U.D.) Fundación Cardiovascular de Colombia, Floridablanca, Colombia (L.E.E.) University of Utah, Salt Lake City (J.C.F.) National and Kapodistrian University of Athens, Attikon University Hospital, Athens (G.F.) Hospital S. Francisco Xavier, Centro Hospitalar Lisboa Ocidental, NOVA Medical School, Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Lisbon, Portugal (C.F.) Commenius University, Bratislava, Slovakia (E.G.) the Department of Cardiology, Queen Giovanna University Hospital and Medical University, Sofia, Bulgaria (A.R.G.) Libin Cardiovascular Institute and Cumming School of Medicine, University of Calgary, Calgary, AB (J.G.H.), and Montreal Heart Institute and Université de Montréal, Montreal (E.O.) - both in Canada the Heart and Vascular Institute, Henry Ford Hospital, Detroit (D.E.L.) the National Clinical Research Center for Cardiovascular Diseases, National Health Commission Key Laboratory of Clinical Research for Cardiovascular Medications, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing (J.L.) Middlemore Hospital, Otahuhu, Auckland, New Zealand (M.L.) St. Vincent's Hospital Sydney, Darlinghurst, NSW, Australia (P.M.) University Clinic of Lomonosov, Moscow State University, Moscow (V.M.) Saitama Citizens Medical Center, Saitama, Japan (S.M.) Institute of Cardiology, Kyiv, Ukraine (A.P.) Wroclaw Medical University, Wroclaw, Poland (P.P.) Instituto do Coração, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Faculdade de Medicina, Universidade de São Paulo, São Paulo (F.J.A.R.) Vilnius University, Vilnius, Lithuania (P.S.) the University of Cape Town, Cape Town, South Africa (K.S.) the Internal Cardiology Department, St. Ann Hospital and Masaryk University Brno, Brno, Czech Republic (J.S.) the Department of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland (T.M.S.) St. John of God Hospital, Budapest, Hungary (J.T.) AZ Sint-Lucas, Ghent, Belgium (H.V.) the University of Medicine and Pharmacy Carol Davila, University and Emergency Hospital, Bucharest, Romania (D.V.) the University of Groningen, Groningen, the Netherlands (A.A.V.) Dokuz Eylul University, Izmir, Turkey (M.B.Y.) and Université de Lorraine, INSERM Investigation Network Initiative Cardiovascular and Renal Clinical Trialists, Centre Hospitalier Régional Universitaire de Nancy, Nancy (F.Z.), and Servier, Suresnes (C.V.) - both in France
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Arias-Mendoza, Alexandra
Autor Arias-Mendoza, Alexandra From the Section of Cardiology, San Francisco Veterans Affairs Medical Center and School of Medicine, University of California, San Francisco, San Francisco (J.R.T.), Amgen, Thousand Oaks (L.S., J.C.L., N.H., S.A.A., C.E.K.), and Cytokinetics, South San Francisco (F.I.M.) - all in California Estudios Clínicos Latino América, Rosario, Argentina (R.D.) the Division of Cardiology, Duke University School of Medicine and Duke Clinical Research Institute, Durham (G.M.F.), and the University of North Carolina, Chapel Hill (K.F.A.) - both in North Carolina the British Heart Foundation Cardiovascular Research Centre (J.J.V.M.) and the Robertson Centre for Biostatistics and Clinical Trials, Institute of Health and Wellbeing (J.G.F.C.), University of Glasgow, Glasgow, and the National Heart and Lung Institute, Imperial College, London (J.G.F.C.) - both in the United Kingdom Cardiology, ASST Spedali Civili, Department of Medical and Surgical Specialties, Radiologic Sciences, and Public Health, University of Brescia, Brescia, Italy (M.M.) the Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston (S.D.S.) the University of Minnesota, Minneapolis (I.A.) Instituto Nacional de Cardiología, Mexico City (A.A.-M.) the Department of Cardiology, Herlev and Gentofte Hospital, and the Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen (T.B.-S.) Saarland University, Universitätsklinikum des Saarlandes, Homburg, Germany (M.B.) Medical University of Vienna, Vienna (D.B.) Pontificia Universidad Católica de Chile, Santiago (R.C.) Complexo Hospitalario Universitario A Coruña, Centro de Investigación Biomédica en Red, Enfermedades Cardiovasculares, Instituto de Investigación Biomédica de A Coruña, Universidade da Coruña, A Coruña, Spain (M.G.C.-L.) the Departments of Cardiology and Health, Medicine and Caring Sciences, Linkoping University, Linkoping, Sweden (U.D.) Fundación Cardiovascular de Colombia, Floridablanca, Colombia (L.E.E.) University of Utah, Salt Lake City (J.C.F.) National and Kapodistrian University of Athens, Attikon University Hospital, Athens (G.F.) Hospital S. Francisco Xavier, Centro Hospitalar Lisboa Ocidental, NOVA Medical School, Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Lisbon, Portugal (C.F.) Commenius University, Bratislava, Slovakia (E.G.) the Department of Cardiology, Queen Giovanna University Hospital and Medical University, Sofia, Bulgaria (A.R.G.) Libin Cardiovascular Institute and Cumming School of Medicine, University of Calgary, Calgary, AB (J.G.H.), and Montreal Heart Institute and Université de Montréal, Montreal (E.O.) - both in Canada the Heart and Vascular Institute, Henry Ford Hospital, Detroit (D.E.L.) the National Clinical Research Center for Cardiovascular Diseases, National Health Commission Key Laboratory of Clinical Research for Cardiovascular Medications, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing (J.L.) Middlemore Hospital, Otahuhu, Auckland, New Zealand (M.L.) St. Vincent's Hospital Sydney, Darlinghurst, NSW, Australia (P.M.) University Clinic of Lomonosov, Moscow State University, Moscow (V.M.) Saitama Citizens Medical Center, Saitama, Japan (S.M.) Institute of Cardiology, Kyiv, Ukraine (A.P.) Wroclaw Medical University, Wroclaw, Poland (P.P.) Instituto do Coração, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Faculdade de Medicina, Universidade de São Paulo, São Paulo (F.J.A.R.) Vilnius University, Vilnius, Lithuania (P.S.) the University of Cape Town, Cape Town, South Africa (K.S.) the Internal Cardiology Department, St. Ann Hospital and Masaryk University Brno, Brno, Czech Republic (J.S.) the Department of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland (T.M.S.) St. John of God Hospital, Budapest, Hungary (J.T.) AZ Sint-Lucas, Ghent, Belgium (H.V.) the University of Medicine and Pharmacy Carol Davila, University and Emergency Hospital, Bucharest, Romania (D.V.) the University of Groningen, Groningen, the Netherlands (A.A.V.) Dokuz Eylul University, Izmir, Turkey (M.B.Y.) and Université de Lorraine, INSERM Investigation Network Initiative Cardiovascular and Renal Clinical Trialists, Centre Hospitalier Régional Universitaire de Nancy, Nancy (F.Z.), and Servier, Suresnes (C.V.) - both in France
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Biering-Sørensen, Tor
Autor Biering-Sørensen, Tor From the Section of Cardiology, San Francisco Veterans Affairs Medical Center and School of Medicine, University of California, San Francisco, San Francisco (J.R.T.), Amgen, Thousand Oaks (L.S., J.C.L., N.H., S.A.A., C.E.K.), and Cytokinetics, South San Francisco (F.I.M.) - all in California Estudios Clínicos Latino América, Rosario, Argentina (R.D.) the Division of Cardiology, Duke University School of Medicine and Duke Clinical Research Institute, Durham (G.M.F.), and the University of North Carolina, Chapel Hill (K.F.A.) - both in North Carolina the British Heart Foundation Cardiovascular Research Centre (J.J.V.M.) and the Robertson Centre for Biostatistics and Clinical Trials, Institute of Health and Wellbeing (J.G.F.C.), University of Glasgow, Glasgow, and the National Heart and Lung Institute, Imperial College, London (J.G.F.C.) - both in the United Kingdom Cardiology, ASST Spedali Civili, Department of Medical and Surgical Specialties, Radiologic Sciences, and Public Health, University of Brescia, Brescia, Italy (M.M.) the Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston (S.D.S.) the University of Minnesota, Minneapolis (I.A.) Instituto Nacional de Cardiología, Mexico City (A.A.-M.) the Department of Cardiology, Herlev and Gentofte Hospital, and the Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen (T.B.-S.) Saarland University, Universitätsklinikum des Saarlandes, Homburg, Germany (M.B.) Medical University of Vienna, Vienna (D.B.) Pontificia Universidad Católica de Chile, Santiago (R.C.) Complexo Hospitalario Universitario A Coruña, Centro de Investigación Biomédica en Red, Enfermedades Cardiovasculares, Instituto de Investigación Biomédica de A Coruña, Universidade da Coruña, A Coruña, Spain (M.G.C.-L.) the Departments of Cardiology and Health, Medicine and Caring Sciences, Linkoping University, Linkoping, Sweden (U.D.) Fundación Cardiovascular de Colombia, Floridablanca, Colombia (L.E.E.) University of Utah, Salt Lake City (J.C.F.) National and Kapodistrian University of Athens, Attikon University Hospital, Athens (G.F.) Hospital S. Francisco Xavier, Centro Hospitalar Lisboa Ocidental, NOVA Medical School, Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Lisbon, Portugal (C.F.) Commenius University, Bratislava, Slovakia (E.G.) the Department of Cardiology, Queen Giovanna University Hospital and Medical University, Sofia, Bulgaria (A.R.G.) Libin Cardiovascular Institute and Cumming School of Medicine, University of Calgary, Calgary, AB (J.G.H.), and Montreal Heart Institute and Université de Montréal, Montreal (E.O.) - both in Canada the Heart and Vascular Institute, Henry Ford Hospital, Detroit (D.E.L.) the National Clinical Research Center for Cardiovascular Diseases, National Health Commission Key Laboratory of Clinical Research for Cardiovascular Medications, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing (J.L.) Middlemore Hospital, Otahuhu, Auckland, New Zealand (M.L.) St. Vincent's Hospital Sydney, Darlinghurst, NSW, Australia (P.M.) University Clinic of Lomonosov, Moscow State University, Moscow (V.M.) Saitama Citizens Medical Center, Saitama, Japan (S.M.) Institute of Cardiology, Kyiv, Ukraine (A.P.) Wroclaw Medical University, Wroclaw, Poland (P.P.) Instituto do Coração, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Faculdade de Medicina, Universidade de São Paulo, São Paulo (F.J.A.R.) Vilnius University, Vilnius, Lithuania (P.S.) the University of Cape Town, Cape Town, South Africa (K.S.) the Internal Cardiology Department, St. Ann Hospital and Masaryk University Brno, Brno, Czech Republic (J.S.) the Department of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland (T.M.S.) St. John of God Hospital, Budapest, Hungary (J.T.) AZ Sint-Lucas, Ghent, Belgium (H.V.) the University of Medicine and Pharmacy Carol Davila, University and Emergency Hospital, Bucharest, Romania (D.V.) the University of Groningen, Groningen, the Netherlands (A.A.V.) Dokuz Eylul University, Izmir, Turkey (M.B.Y.) and Université de Lorraine, INSERM Investigation Network Initiative Cardiovascular and Renal Clinical Trialists, Centre Hospitalier Régional Universitaire de Nancy, Nancy (F.Z.), and Servier, Suresnes (C.V.) - both in France
Nursing & Allied Health Database (ProQuest) od 1980-01-03 do Před 3 měsíci
Health & Medicine (ProQuest) od 1980-01-03 do Před 3 měsíci
Family Health Database (ProQuest) od 1980-01-03 do Před 3 měsíci
Psychology Database (ProQuest) od 1980-01-03 do Před 3 měsíci
Health Management Database (ProQuest) od 1980-01-03 do Před 3 měsíci
Public Health Database (ProQuest) od 1980-01-03 do Před 3 měsíci
PubMed
33185990
DOI
10.1056/nejmoa2025797
Knihovny.cz E-zdroje
BACKGROUND: The selective cardiac myosin activator omecamtiv mecarbil has been shown to improve cardiac function in patients with heart failure with a reduced ejection fraction. Its effect on cardiovascular outcomes is unknown. METHODS: We randomly assigned 8256 patients (inpatients and outpatients) with symptomatic chronic heart failure and an ejection fraction of 35% or less to receive omecamtiv mecarbil (using pharmacokinetic-guided doses of 25 mg, 37.5 mg, or 50 mg twice daily) or placebo, in addition to standard heart-failure therapy. The primary outcome was a composite of a first heart-failure event (hospitalization or urgent visit for heart failure) or death from cardiovascular causes. RESULTS: During a median of 21.8 months, a primary-outcome event occurred in 1523 of 4120 patients (37.0%) in the omecamtiv mecarbil group and in 1607 of 4112 patients (39.1%) in the placebo group (hazard ratio, 0.92; 95% confidence interval [CI], 0.86 to 0.99; P = 0.03). A total of 808 patients (19.6%) and 798 patients (19.4%), respectively, died from cardiovascular causes (hazard ratio, 1.01; 95% CI, 0.92 to 1.11). There was no significant difference between groups in the change from baseline on the Kansas City Cardiomyopathy Questionnaire total symptom score. At week 24, the change from baseline for the median N-terminal pro-B-type natriuretic peptide level was 10% lower in the omecamtiv mecarbil group than in the placebo group; the median cardiac troponin I level was 4 ng per liter higher. The frequency of cardiac ischemic and ventricular arrhythmia events was similar in the two groups. CONCLUSIONS: Among patients with heart failure and a reduced ejection, those who received omecamtiv mecarbil had a lower incidence of a composite of a heart-failure event or death from cardiovascular causes than those who received placebo. (Funded by Amgen and others; GALACTIC-HF ClinicalTrials.gov number, NCT02929329; EudraCT number, 2016-002299-28.).
- MeSH
- kardiotonika škodlivé účinky farmakologie terapeutické užití MeSH
- kardiovaskulární nemoci mortalita MeSH
- kontrakce myokardu účinky léků MeSH
- lidé středního věku MeSH
- lidé MeSH
- močovina škodlivé účinky analogy a deriváty farmakologie terapeutické užití MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- srdeční myosiny účinky léků metabolismus MeSH
- systolické srdeční selhání farmakoterapie metabolismus patofyziologie MeSH
- tepový objem MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- klinické zkoušky, fáze III MeSH
- multicentrická studie MeSH
- práce podpořená grantem MeSH
- randomizované kontrolované studie MeSH
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