The CARIATIDE study was designed to assess the impact of educational materials (EMs) on compliance and persistence rates with aromatase inhibitor (AI) treatment in postmenopausal women with hormone-receptor-positive early breast cancer. Patients were randomized to standard AI treatment (Group A; N = 1379) or standard AI treatment plus EMs containing information on a range of breast-cancer-related topics (Group B; N = 1379). Standardized questionnaires assessed investigator-perceived levels of care and evaluated patient compliance and behavior. At 1 year, there was no significant difference in compliance between Group A and Group B (81% vs. 82%, p = 0.4524). However, higher compliance in patients receiving EMs was observed in Sweden/Finland (p = 0.0246). Compliance with initial AI and persistence rate were not significantly altered by EM. Other factors associated with improved compliance, irrespective of EMs, e.g. administration of chemotherapy were identified.
- MeSH
- adherence k farmakoterapii statistika a číselné údaje MeSH
- adjuvantní chemoterapie MeSH
- hormonální protinádorové látky terapeutické užití MeSH
- inhibitory aromatasy terapeutické užití MeSH
- lidé středního věku MeSH
- lidé MeSH
- lymfadenektomie MeSH
- mastektomie MeSH
- nádory prsu farmakoterapie MeSH
- nitrily terapeutické užití MeSH
- postmenopauza MeSH
- senioři MeSH
- triazoly terapeutické užití MeSH
- vzdělávání pacientů jako téma metody MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- multicentrická studie MeSH
- práce podpořená grantem MeSH
- randomizované kontrolované studie MeSH
