OBJECTIVES: The main goal of the study was to describe the demographic, epidemiological, clinical and laboratory characteristics of a monitored group of patients with psoriasis to assess the prevalence of cardiovascular comorbidities and to define the cardiovascular risk profile. METHODS: One hundred and ninety outpatients aged over 18 were included in the prospective observational cross-sectional study. Demographic and clinical data were obtained from patients. The severity of psoriasis was evaluated using the Psoriasis Area and Severity Index (PASI) and the Dermatology Life Quality Index (DLQI). The results of laboratory testing were identified based on patient health records. RESULTS: Based on an evaluation of psoriasis phenotypes, 150 patients (78.95%) suffered from plaque psoriasis, 18 (9.5%) from palmoplantar psoriasis, 11 (5.8%) from guttate psoriasis, 6 (3.2%) from generalized pustular psoriasis, and 5 (2.6%) from erythrodermic psoriasis. The personal medical history discovered the occurrence of arterial hypertension in 83 patients (43.7%), the occurrence of depression in 49 patients (25.8%), type 2 diabetes in 29 patients (15.3%), and dyslipidaemia in 48 patients (25.3%). CONCLUSION: It is noteworthy that psoriasis may be demonstrated as a multi-system disease which does not only affect the skin and its adnexa. The association of psoriasis with comorbidities may significantly increase morbidity and total mortality as well as the demands for health care provision.
- MeSH
- diabetes mellitus 2. typu * epidemiologie MeSH
- kardiovaskulární nemoci * epidemiologie MeSH
- kvalita života MeSH
- lidé MeSH
- prevalence MeSH
- průřezové studie MeSH
- psoriáza * epidemiologie MeSH
- rizikové faktory kardiovaskulárních chorob MeSH
- rizikové faktory MeSH
- stupeň závažnosti nemoci MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- pozorovací studie MeSH
Úvod: Hidradenitis suppurativa (HS) a chronické zápalové ochorenia čreva (IBD) sú navzájom asociované. Prevalencia IBD u pacientov s HS nie je úplne objasnená. Cieľom práce bolo zistiť prevalenciu IBD u HS pacientov a vyhodnotiť rizikové faktory a možný fenotyp pacientov HS a IBD. Metodika: Monocentrickou retrospektívnou analýzou dát u 241 pacientov s HS sme na základe zdravotnej dokumentácie určili výskyt IBD. Následne sme vyhodnocovali epidemiologické faktory HS. Výsledky: IBD sme potvrdili u 5,8 % pacientov. Z uvedeného počtu bolo 13 (92,9 %) pacientov s Crohnovou chorobou a 1 (7,1 %) pacient s ulceróznou kolitídou. Gastroenterológom bolo odoslaných 8 (57,1 %) pacientov a u 6 (42,9 %) pacientov sme našli asociáciu náhodne v rámci dermatologického vyšetrenia. Práca nepotvrdila jednoznačne odlišný fenotyp pacienta, ktorý je pri ochorení HS asociovaný s IBD. Upozorňujeme na výskyt možných spoločných komorbidít a rizikových faktorov ako abúzus fajčenia a obezitu. Diskusia: Práca potvrdzuje dostupné literárne údaje, významnú asociáciu HS a CD a nižšiu pri HS a UC. Záver: Prevalencia IBD u pacientov s HS je 5,8 %, u pacientov s HS a IBD sme nepotvrdili jednoznačne odlišný fenotyp ochorenia.
Introduction: Association between hidradenitis suppurativa (HS) and chronic inflammatory bowel disease (IBD) exists. Prevalence of IBD in patients with HS is not clear. The aim of this paper is to determine the prevalence of IBD in patients with HS, evaluate risk factors and possible phenotype of patients with HS and IBD. Methods: Single center retrospective analysis of 241 patients with HS was carried out and medical files were searched for inflammatory bowel disease accordingly. Epidemiologic data of HS were collected. Results: IBD had a prevalence of 5.8%. Out of this number 13 (92.9%) suffered from Crohn’s disease (CD) and 1 (7.1%) from ulcerative colitis (UC). Eight patients (57.1%) were referred to the dermatologist by gastroenterologist and in six patients (42.9%) history of IBD was detected by dermatologist during routine examination. Special phenotype of the disease associated with IBD was not confirmed. The study points out possible existence of common comorbidities and risk factors such as smoking and obesity. Discussion: Our study confirmed similar data like those available in literature, where strong association between CD and HS is present and weaker with UC and HS. Conclusion: The prevalence of IBD in HS patients (5.8%) however these patients do not have a distinct HS phenotype.
