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Autor: Patterson, Cam

5 záznamů v Medvik Filtry

Článek online

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Klionsky, Daniel J
Autor Klionsky, Daniel J boc University of Michigan , Department of Molecular , Cellular, and Developmental Biology , Ann Arbor , MI , USA. bog University of Michigan, Life Sciences Institute , Ann Arbor , MI , USA
Abdelmohsen, Kotb
Autor Abdelmohsen, Kotb afh National Institute on Aging, National Institutes of Health, Biomedical Research Center, RNA Regulation Section, Laboratory of Genetics , Baltimore , MD , USA
Abe, Akihisa
Autor Abe, Akihisa auo Tokyo Medical University , Department of Biochemistry , Tokyo , Japan
Abedin, Md Joynal
Autor Abedin, Md Joynal bot University of Minnesota , Department of Lab Medicine and Pathology , Minneapolis , MN , USA
Abeliovich, Hagai
Autor Abeliovich, Hagai pi Hebrew University of Jerusalem, Faculty of Agriculture, Food, and Environment, Biochemistry and Food Science , Rehovot , Israel
Acevedo Arozena, Abraham
Autor Acevedo Arozena, Abraham adi MRC Harwell, Mammalian Genetics Unit , Oxfordshire , UK
Adachi, Hiroaki
Autor Adachi, Hiroaki bqf University of Occupational and Environmental Health School of Medicine , Department of Neurology , Fukuoka , Japan
Adams, Christopher M
Autor Adams, Christopher M ble University of Iowa , Department of Internal Medicine , Iowa City , IA , USA
Adams, Peter D
Autor Adams, Peter D be Beatson Institute for Cancer Research, University of Glasgow , Glasgow , UK
Adeli, Khosrow
Autor Adeli, Khosrow bxe University of Toronto, Molecular Structure and Function, Research Institute, Hospital for Sick Children , Toronto, ON , Canada

Autophagy. 2016 ; 12 (1) : 1-222.

ISSN 1554-8635
Medvik
Zdroj

MeSH
autofagie * fyziologie MeSH
biotest metody normy MeSH
lidé MeSH
počítačová simulace MeSH
zvířata MeSH
Check Tag
lidé MeSH
zvířata MeSH
Publikační typ
časopisecké články MeSH
Research Support, N.I.H., Extramural MeSH
směrnice MeSH

Článek

Nové poznatky v signalizaci kostních morfogenetických proteinů - zaostřeno na angiogenezi
[New insights into bone morphogenetic protein signaling: focus on angiogenesis]

Current Opinion in Hematology. 2009 ; 1 (3) : 67-72.

ISSN 1803-683X
Medvik
Zdroj

The role of bone morphogenetic proteins (BMPs) in vasculogenesis is still not well understood, despite many recent developments in this area of research. In this review, we discuss the most recent studies that identify new critical mechanisms through which BMP signaling acts with a focus on angiogenesis. RECENT FINDINGS: New evidence brought to light over the last few years suggests that BMP-binding proteins, formerly thought of as antagonists, can also increase BMP activity under certain conditions. It has also recently been determined that components of the extracellular matrix are involved in the BMP signaling pathways that regulate angiogenesis. Through the BMP pathway, myosin-X and cyclooxygenase 2 serve as target genes that have been determined to play a role in blood vessel formation. BMPs also conduct Smad-independent signaling and crosstalk with other pathways. Finally, BMPs have been shown to play an antiangiogenic role in specific settings. SUMMARY: Better understanding of the BMP signaling pathway and its regulators can have potentially great effects on therapeutic strategies from cardiovascular disease to cancer.