The ability of Linaria vulgaris (Scrophulariaceae) infusion to act as a scavenger of 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical, reactive oxygen species (superoxide radical, hydroxyl radical, hypochlorous acid (HOCl)) and nitric oxide was investigated. The obtained data indicate that the infusion has a good scavenging activity against superoxide radical and is a very potent nitric oxide and DPPH scavenger. In hydroxyl radical assay a pro-oxidant capacity was noticed, especially for concentrations higher than 31.25 microg mL(-1). No effect was found against HOCl. A phytochemical study of this extract was also performed. The HPLC/UV analysis allowed the identification and quantification of eight organic acids (oxalic, aconitic, citric, ketoglutaric, ascorbic, malic, shikimic and fumaric acids). The phenolic composition of the lyophilised infusion was also determined by HPLC/DAD and four compounds were quantified, but, despite its high content, only linarin was managed to be identified.

• MeSH
• bifenylové sloučeniny chemie   MeSH
• fenoly analýza   MeSH
• financování organizované MeSH
• hydraziny chemie   MeSH
• hydroxylový radikál chemie   MeSH
• kyselina chlorná chemie   MeSH
• kyseliny karboxylové analýza   MeSH
• Linaria chemie   MeSH
• oxid dusnatý chemie   MeSH
• pikráty MeSH
• scavengery volných radikálů analýza   MeSH
• superoxidy chemie   MeSH
• vysokoúčinná kapalinová chromatografie MeSH