This review introduces β-fluorophosphonates as useful synthons and fluoroalkyl transfer reagents. The remarkable biological activity of the phosphonates is also mentioned. The main emphasis is put on synthetic applications of the following fluorinated phosphonates: diethyl (difluoromethyl)phosphonate (1), diethyl (trifluoromethyl)phosphonate (2), tetraethyl (fluoromethylene)bis¬phosphonate (3), diethyl [(fluoromethyl) (phenylsulfonyl)methyl]phosphonate (McCathy’s reagent) (4), and diethyl (fluoronitromethyl)phosphonate (5). The review is focused on the chemistry of the synthons.

• MeSH
• aktivní transport MeSH
• alkylace MeSH
• antivirové látky MeSH
• bisfosfonáty * chemie   klasifikace   MeSH
• farmakologické účinky MeSH
• fluor chemie   MeSH
• inhibitory enzymů MeSH
• lidé MeSH
• organická chemie MeSH
• organofosfonáty * chemie   klasifikace   MeSH
• pojmy organické chemie MeSH
• vztahy mezi strukturou a aktivitou * MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• práce podpořená grantem MeSH