Calprotectin represents an interesting peptide known to be involved in the pathophysiology of various inflammatory processes. Being secreted from activated neutrophils and monocytes under various conditions, it can also be found in the extracellular fluids and serve as a biomarker of ongoing inflammation, which property is currently used in the monitoring of inflammatory bowel diseases. Recent studies, however, suggest that calprotectin could serve as an important prognostic factor for cardiovascular and cardiometabolic diseases, since these are occurring on the basis of low-grade chronic inflammation. We assume that calprotectin may represent a useful marker in predicting the course of atherosclerotic process, coronary artery disease and acute coronary syndromes. Our review is focused on the importance of calprotectin in the diagnosis and prognostic stratification in the field of cardiometabolic risk.
- MeSH
- akutní koronární syndrom patofyziologie MeSH
- ateroskleróza etiologie MeSH
- biologické markery MeSH
- idiopatické střevní záněty patofyziologie MeSH
- kardiovaskulární nemoci etiologie patofyziologie MeSH
- leukocytární L1-antigenní komplex fyziologie MeSH
- lidé MeSH
- nemoci koronárních tepen patofyziologie MeSH
- prognóza MeSH
- riziko MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- přehledy MeSH
