Drug-eluting stents (DES) are the recommended stents for primary percutaneous coronary intervention (PCI). This study aimed to determine why interventional cardiologists used non-DES and how it influenced patient prognoses. The efficacy and safety outcomes of the different stents were also compared in patients treated with either prasugrel or ticagrelor. Of the PRAGUE-18 study patients, 749 (67.4%) were treated with DES, 296 (26.6%) with bare-metal stents (BMS), and 66 (5.9%) with bioabsorbable vascular scaffold/stents (BVS) between 2013 and 2016. Cardiogenic shock at presentation, left main coronary artery disease, especially as the culprit lesion, and right coronary artery stenosis were the reasons for selecting a BMS. The incidence of the primary composite net-clinical endpoint (EP) (death, nonfatal myocardial infarction, stroke, serious bleeding, or revascularization) at seven days was 2.5% vs. 6.3% and 3.0% in the DES, vs. with BMS and BVS, respectively (HR 2.7; 95% CI 1.419-5.15, p = 0.002 for BMS vs. DES and 1.25 (0.29-5.39) p = 0.76 for BVS vs. DES). Patients with BMS were at higher risk of death at 30 days (HR 2.20; 95% CI 1.01-4.76; for BMS vs. DES, p = 0.045) and at one year (HR 2.1; 95% CI 1.19-3.69; p = 0.01); they also had a higher composite of cardiac death, reinfarction, and stroke (HR 1.66; 95% CI 1.0-2.74; p = 0.047) at one year. BMS were associated with a significantly higher rate of primary EP whether treated with prasugrel or ticagrelor. In conclusion, patients with the highest initial risk profile were preferably treated with BMS over BVS. BMS were associated with a significantly higher rate of cardiovascular events whether treated with prasugrel or ticagrelor.

• Publikační typ
• časopisecké články MeSH

"Syndesmologia siue historia ligamentorum corporis humani", published in 1742 by a German anatomist Josias Weitbrecht (1702-1747), who for a long time lived and worked in St. Petersburg, is the first comprehensive textbook of syndesmology. The accuracy and quality of the accompanying illustrations are fascinating, even after almost 300 years. Weitbrecht was also the first to describe the synovial folds of the hip joint, later named after him as the retinacula of Weitbrecht. This eponym appeared in the first half of the nineteenth century in the studies of femoral neck fractures published in the UK. In the study of syndesmology, Weitbrecht was followed by a number of outstanding authors of that time, such as Meckel, Barkow, Arnold, Henle, Humphry and Fick.

• MeSH
• anatomie dějiny   MeSH
• anatomové dějiny   MeSH
• dějiny 18. století MeSH
• dějiny 19. století MeSH
• kloubní pouzdro anatomie a histologie   MeSH
• kyčelní kloub anatomie a histologie   MeSH
• lékařské ilustrace dějiny   MeSH
• lidé MeSH
• ligamenta anatomie a histologie   MeSH
• učebnice jako téma dějiny   MeSH
• Check Tag
• dějiny 18. století MeSH
• dějiny 19. století MeSH
• lidé MeSH
• mužské pohlaví MeSH
• Publikační typ
• biografie MeSH
• časopisecké články MeSH
• historické články MeSH
• přehledy MeSH