N-butanol, a valued solvent and potential fuel extender, could possibly be produced by fermentation using either native producers, i.e. solventogenic Clostridia, or engineered platform organisms such as Escherichia coli or Pseudomonas species, if the main process obstacle, a low final butanol concentration, could be overcome. A low final concentration of butanol is the result of its high toxicity to production cells. Nevertheless, bacteria have developed several mechanisms to cope with this toxicity and one of them is active butanol efflux. This review presents information about a few well characterized butanol efflux pumps from Gram-negative bacteria (P. putida and E. coli) and summarizes knowledge about putative butanol efflux systems in Gram-positive bacteria.

• MeSH
• bakteriální proteiny MeSH
• biologický transport MeSH
• Escherichia coli * MeSH
• membránové transportní proteiny MeSH
• metabolické inženýrství MeSH
• mikrobiální viabilita MeSH
• n-butanol * analýza   metabolismus   toxicita   MeSH
• proteiny z Escherichia coli MeSH
• Pseudomonas putida * MeSH
• rozpouštědla MeSH
• transportní proteiny MeSH
• Publikační typ
• časopisecké články MeSH
• přehledy MeSH