Sympathetic nervous system (SNS) undergoes a prolonged period of fetal and neonatal development and maturation during which is vulnerable to a variety of influences (e.g. painful experiences). Thus, we aimed to evaluate SNS activity at rest and in response to stressful stimulus (pain) within the earliest postnatal life in healthy term neonates using electrodermal activity (EDA) measures. In twenty eutrophic healthy term neonates EDA was recorded within the first two hours after birth (measurement 1 - M1) and 72 h after birth (measurement 2 - M2) at rest and in response to pain (M1 - intramuscular K vitamin administration; M2 - heel stick). Evaluated parameters were skin conductance level (SCL), non-specific skin conductance responses (NS.SCRs), skin SCL 10 s before pain stimulus (SCL_10 before pain), skin conductance response (SCR) peak after pain stimulus, SCL 10 s after pain stimulus (SCL_10 after pain), SCR magnitude, latency, SCR rise/decline time, SCR half recovery time. SCL was significantly decreased at rest during M2 compared to M1 (p=0.010). SCL_10 before pain, SCR peak after pain, and SCL_10 after pain stimulus were significantly decreased in M2 compared to M1 (p=0.014, p=0.020, p=0.011, respectively). SCL was significantly decreased and NS.SCRs were significantly higher in the recovery period after the pain stimulus during M2 compared to M1 (p=0.015, p=0.032, respectively). Our results indicate EDA parameters sensitive to detect sympathetic changes during the earliest postnatal life reflecting its potential in early diagnosis of the autonomic maturation - linked pathological states in neonates.

• MeSH
• autonomní nervový systém MeSH
• bolest diagnóza   MeSH
• galvanická kožní odpověď * MeSH
• lidé MeSH
• novorozenec MeSH
• reakční čas MeSH
• sympatický nervový systém * fyziologie   MeSH
• Check Tag
• lidé MeSH
• novorozenec MeSH
• Publikační typ
• časopisecké články MeSH

Mitral valve prolapse (MVP) belongs to cardiac disorders characterized by impaired closure of mitral leaflets. We studied adolescent group of patients with MVP suffering from symptomatology that cannot be explained by mitral regurgitation alone. Several studies suggested that symptoms can be explained by autonomic, in particular sympathetic-linked dysfunction. Thus, we assessed non-invasive sympathetic indices of blood pressure and heart rate variability and electrodermal activity (EDA). Fifty-three adolescents with MVP (age: 15.1+/-0.4 years) and 43 healthy age- and gender-matched adolescents (age: 14.9+/-0.4 years) were examined. Blood pressure, heart rate and EDA were continuously recorded during 6-min rest. Evaluated parameters were: low frequency band of systolic blood pressure variability, systolic, diastolic and mean blood pressure, mean RR interval, cardiac sympathetic indices: symbolic dynamics (0V%), left ventricular ejection time (LVET), pre-ejection period (PEP), and EDA. Our findings revealed significantly higher systolic, diastolic, and mean blood pressure values, shortened mean RR interval, increased 0V%, and shortened LVET in MVP patients vs. controls (p=0.028, p<0.001, p=0.002, p<0.001, p=0.050, p<0.001; respectively). Our study revealed enhanced cardiovascular sympathetic regulation in adolescent MVP patients. We suggest that evaluation of non-invasive sympathetic parameters could represent potential biomarkers for early diagnosis of cardiovascular complications associated with MVP already at adolescent age.

• MeSH
• funkce levé komory srdeční MeSH
• galvanická kožní odpověď MeSH
• krevní tlak MeSH
• lidé MeSH
• mitrální insuficience diagnóza   patofyziologie   MeSH
• mladiství MeSH
• prognóza MeSH
• prolaps mitrální chlopně diagnóza   patofyziologie   MeSH
• srdce diagnostické zobrazování   inervace   MeSH
• srdeční frekvence MeSH
• studie případů a kontrol MeSH
• sympatický nervový systém patofyziologie   MeSH
• věkové faktory MeSH
• Check Tag
• lidé MeSH
• mladiství MeSH
• mužské pohlaví MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH

It has been suggested that sympathetic activity, measured as changes in electrical skin impedance (SI), can be used to assess the adequacy of general anesthesia. Our prospective study investigated if measurements of skin impedance can determine levels of sedation induced by midazolam. Twenty-seven patients scheduled for arthroscopy requiring general anesthesia were served as their own control. These were blinded to the order of injections by telling them that they will be randomly administered a placebo (saline) orsedative agent. A DM 3900 multimeter was used for SI measurements. The degree of sedation was measured using the modified Observer's Assessment of Alertness and Sedation (mOAAS) scale. Resting SI values were noted, and all participants were then administered the placebo followed 5 min later by midazolam 2 mg i.v. Five min after that, patients were administered standard general anesthesia with propofol, oxygen, nitrous oxide 60 %, and isoflurane 1 MAC via a laryngeal mask, and sufentanil 5 - 10 μg. SI significantly increased after administration of midazolam and induction of anesthesia. There were no significant differences between pre-administration (baseline) and placebo and end of surgery and end of anesthesia with closed eyes. There were highly significant differences (p<0.001) between pre-administration vs. midazolam, placebo vs. midazolam, pre-administration vs. induction of anesthesia. We found slight correlation between mOAAS and SI. There were no significant changes between the end of surgery and the end of anesthesia with closed eyes, but SI significantly decreased (p<0.01) after eyes opened.

• MeSH
• časové faktory MeSH
• celková anestezie MeSH
• dospělí MeSH
• dvojitá slepá metoda MeSH
• elektrická impedance MeSH
• galvanická kožní odpověď účinky léků   MeSH
• hypnotika a sedativa terapeutické užití   MeSH
• kůže inervace   MeSH
• lidé středního věku MeSH
• lidé MeSH
• midazolam terapeutické užití   MeSH
• probouzení z anestezie * MeSH
• prospektivní studie MeSH
• sympatický nervový systém účinky léků   fyziologie   MeSH
• vědomí účinky léků   MeSH
• Check Tag
• dospělí MeSH
• lidé středního věku MeSH
• lidé MeSH
• mužské pohlaví MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• randomizované kontrolované studie MeSH
• Geografické názvy
• Česká republika MeSH

Snakes have been important ambush predators of both primates and human hunter-gatherers throughout their co-evolutionary history. Viperid snakes in particular are responsible for most fatal venomous snakebites worldwide and thus represent a strong selective pressure. They elicit intense fear in humans and are easily recognizable thanks to their distinctive morphotype. In this study, we measured skin resistance (SR) and heart rate (HR) in human subjects exposed to snake pictures eliciting either high fear (10 venomous viperid species) or disgust (10 nonvenomous fossorial species). Venomous snakes subjectively evaluated as frightening trigger a stronger physiological response (higher SR amplitude) than repulsive non-venomous snakes. However, stimuli presented in a block (more intense stimulation) do not trigger a stronger emotional response compared to sequentially presented stimuli (less intense stimulation). There are significant interindividual differences as subjects with high fear of snakes confronted with images of viperid snakes show stronger, longer-lasting, and more frequent changes in SR and higher HR compared to low-fear subjects. Thus, we show that humans demonstrate a remarkable ability to discriminate between dangerous viperids and harmless fossorial snakes, which is also reflected in distinct autonomous body responses.

• MeSH
• autonomní nervový systém fyziologie   MeSH
• biologická evoluce MeSH
• dospělí MeSH
• galvanická kožní odpověď fyziologie   MeSH
• hadí jedy otrava   MeSH
• hadi * MeSH
• lidé MeSH
• mladiství MeSH
• mladý dospělý MeSH
• odpor MeSH
• psychofyziologie MeSH
• psychologické modely MeSH
• psychometrie MeSH
• srdeční frekvence fyziologie   MeSH
• strach fyziologie   psychologie   MeSH
• světelná stimulace MeSH
• uštknutí hadem psychologie   MeSH
• zvířata MeSH
• Check Tag
• dospělí MeSH
• lidé MeSH
• mladiství MeSH
• mladý dospělý MeSH
• mužské pohlaví MeSH
• ženské pohlaví MeSH
• zvířata MeSH
• Publikační typ
• časopisecké články MeSH
• práce podpořená grantem MeSH

Analyses of user experience in the electronic entertainment industry currently rely on self-reporting methods, such as surveys, ratings, focus group interviews, etc. We argue that self-reporting alone carries inherent problems-mainly the misinterpretation and temporal delay during longer experiments-and therefore, should not be used as a sole metric. To tackle this problem, we propose the possibility of modeling consumer experience using psychophysiological measures and demonstrate how such models can be trained using machine learning methods. We use a machine learning approach to model user experience using real-time data produced by the autonomic nervous system and involuntary psychophysiological responses. Multiple psychophysiological measures, such as heart rate, electrodermal activity, and respiratory activity, have been used in combination with self-reporting to prepare training sets for machine learning algorithms. The training data was collected from 31 participants during hour-long experiment sessions, where they played multiple video-games. Afterwards, we trained and compared the results of four different machine learning models, out of which the best one produced ∼96% accuracy. The results suggest that psychophysiological measures can indeed be used to assess the enjoyment of digital entertainment consumers.

• MeSH
• algoritmy MeSH
• autonomní nervový systém fyziologie   MeSH
• dospělí MeSH
• galvanická kožní odpověď fyziologie   MeSH
• lidé MeSH
• mladý dospělý MeSH
• psychofyziologie metody   MeSH
• srdeční frekvence fyziologie   MeSH
• strojové učení MeSH
• videohry psychologie   MeSH
• Check Tag
• dospělí MeSH
• lidé MeSH
• mladý dospělý MeSH
• mužské pohlaví MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH

Introduction-Aim: Newer methods, such as infrared digital pupillometry and electrodermal activity (EDA) measurement have been suggested as good alternatives for analgesia monitoring in critically ill patients. This study analyzed EDA changes due to pain stimulus in sedated adult critical care patients Methods: Skin conductance variability, selected hemodynamic and respiratory parameters, Bispectral index (BIS) and ambient noise level, were monitored during 4 hour routine daytime in an adult ICU. 4h-Measurements were divided into 2 groups, based upon the sedation level of the patients: Group A - Ramsay Sedation Score 2-4 and Group B - Ramsay Sedation Score of 5-6. Selected recordings before and after pain stimulus were performed. The stimulus chosen was the pressure applied to nail bed for 10 sec, which was performed routinely during neurological examination. Patients' demographics, laboratory exams and severity scores were recorded. Pain status evaluation before every event was also performed by 2 independent observers via Critical Care Pain Observation Tool (CPOT) and Adult Non Verbal Pain Score (ANVPS) Results: In both groups the rate of EDA changes was greater than other monitoring parameters: more in Group A than in Group B. Yet, the difference between groups was not statistically significant. CONCLUSION: EDA measurements are greater to pain stimuli, than cardiovascular, respiratory or even BIS monitoring. These encouraging results suggest that, further studies are needed to better define EDA role in ICU.

• MeSH
• analgosedace * MeSH
• fyzikální stimulace * MeSH
• galvanická kožní odpověď * MeSH
• jednotky intenzivní péče MeSH
• lidé středního věku MeSH
• lidé MeSH
• měření bolesti * MeSH
• monitorování fyziologických funkcí * MeSH
• pilotní projekty MeSH
• prospektivní studie MeSH
• senioři MeSH
• Check Tag
• lidé středního věku MeSH
• lidé MeSH
• mužské pohlaví MeSH
• senioři MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• pozorovací studie MeSH

• MeSH
• behaviorismus dějiny   MeSH
• biofeedback (psychologie) fyziologie   klasifikace   metody   MeSH
• dějiny 20. století MeSH
• dějiny lékařství MeSH
• elektroencefalografie metody   trendy   využití   MeSH
• elektromyografie metody   přístrojové vybavení   trendy   MeSH
• experimenty na zvířatech MeSH
• galvanická kožní odpověď fyziologie   MeSH
• kybernetika dějiny   metody   trendy   MeSH
• lidé MeSH
• neurofeedback klasifikace   metody   přístrojové vybavení   MeSH
• operantní podmiňování fyziologie   klasifikace   MeSH
• počítače trendy   využití   MeSH
• počítačové metodologie MeSH
• spektrální analýza metody   využití   MeSH
• systémová analýza MeSH
• termografie metody   trendy   využití   MeSH
• učení fyziologie   klasifikace   MeSH
• Check Tag
• dějiny 20. století MeSH
• lidé MeSH
• Geografické názvy
• Spojené státy americké MeSH

• MeSH
• biofeedback (psychologie) * fyziologie   klasifikace   metody   MeSH
• biomedicínské technologie * metody   přístrojové vybavení   trendy   MeSH
• elektroencefalografie metody   trendy   využití   MeSH
• elektromyografie metody   trendy   využití   MeSH
• galvanická kožní odpověď fyziologie   MeSH
• lidé MeSH
• neurofeedback * fyziologie   klasifikace   metody   MeSH
• neurofyziologický monitoring metody   přístrojové vybavení   využití   MeSH
• termografie metody   trendy   využití   MeSH
• Check Tag
• lidé MeSH

• MeSH
• autonomní nervový systém fyziologie   MeSH
• biofeedback (psychologie) fyziologie   klasifikace   metody   MeSH
• centrální nervový systém fyziologie   MeSH
• dýchání MeSH
• elektroencefalografie metody   využití   MeSH
• elektrokardiografie metody   využití   MeSH
• elektromyografie metody   využití   MeSH
• emoce fyziologie   MeSH
• emoční expresivita fyziologie   MeSH
• fyziologie kůže MeSH
• galvanická kožní odpověď MeSH
• lidé MeSH
• psychofyziologie metody   přístrojové vybavení   trendy   MeSH
• srdeční frekvence MeSH
• statistika jako téma MeSH
• svalový tonus fyziologie   MeSH
• tréninková simulace metody   trendy   MeSH
• výchova a vzdělávání metody   trendy   MeSH
• zpětná vazba * MeSH
• Check Tag
• lidé MeSH

Research based on self-reported data often indicates that women are the more emotional sex. The present study examined differences in emotion between the sexes across two components of the emotional process: subjective experience and physiological reactions to emotional stimuli. During the experimental study, participants (N=124; 22.5±2.88; 51 males) subjectively rated their emotional experience (valence and intensity) towards presented positive and negative affective stimuli, while physiological reactions (facial electromyography, heart rate, skin conductance, and finger skin temperature) were measured during expositions. Results from self-reports suggest that women declared more intensive emotional experiences for positive and negative stimuli and rated negative stimuli as more negative in comparison to men. Physiological measurements showed differences between the sexes in the physiological baseline measurements (facial electromyography, skin conductance and finger skin temperature). However, physiological responses towards positive or negative emotional stimuli did not prove to be different between men and women, except for finger skin temperature. Relations between self-reported subjective experiences and physiological changes were weak and insignificant. Collectively, our findings suggest certain emotional differences experienced between men and women. These differences can be found specifically in self-reported subjective experiences, while significant differences were not predominantly present in recorded physiological reactions.

• MeSH
• dospělí MeSH
• elektromyografie MeSH
• emoce fyziologie   MeSH
• galvanická kožní odpověď fyziologie   MeSH
• lidé MeSH
• mladý dospělý MeSH
• obličejové svaly fyziologie   MeSH
• pohlavní dimorfismus * MeSH
• teplota kůže fyziologie   MeSH
• Check Tag
• dospělí MeSH
• lidé MeSH
• mladý dospělý MeSH
• mužské pohlaví MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• práce podpořená grantem MeSH