BACKGROUND: Person-centred care (PCC) is a fundamental principle in general practice, emphasising practices tailored to individual patient preferences, needs, and values. Despite the importance of PCC, general practitioners (GPs) face obstacles in effectively implementing it, with associated factors remaining unclear. OBJECTIVES: The PACE GP/FP study aims to explore GPs' attitudes towards PCC and the factors facilitating or hindering its implementation in daily practice across European countries. This paper outlines the PACE GP/FP study protocol. METHODS: The cross-sectional design with data collection via an online survey distribution to GPs in 24 European countries. Study instruments include two validated questionnaires (Perceived Stress Scale (PSS) and Patient Physician Orientation Scale (PPOS)) and additional items covering general information about the doctor and their practice, as well as facilitators and barriers to PCC. These additional items were specifically developed for the study, translated using the forward-backward method, evaluated through cognitive debriefing, and integrated into the REDCap platform to create language and country-specific survey links. The STROBE checklist guides the reporting of the manuscript. CONCLUSION: The PACE GP/FP study will provide a comprehensive exploration of GPs' attitudes towards PCC and the factors shaping its practice in Europe. The findings from the PACE GP/FP study will provide evidence for designing future implementation strategies and guide targeted interventions to promote PCC in primary care across Europe.

• Klíčová slova
• Primary health care, general practice, person-centred care,
• MeSH
• lidé MeSH
• péče orientovaná na pacienta * MeSH
• postoj zdravotnického personálu * MeSH
• praktické lékařství organizace a řízení   MeSH
• praktičtí lékaři * psychologie   MeSH
• průřezové studie MeSH
• průzkumy a dotazníky MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• časopisecké články MeSH
• Geografické názvy
• Evropa MeSH

ABSTRACTBackground: European health care workers recently experienced serious challenges to their mental health. Following the extremely stressful experience of the COVID-19 pandemic, the war in Ukraine caused a humanitarian influx of refugees in need of social and healthcare. We aimed to explore: (1) how working with refugees has affected the mental well-being of health care workers in the context of the COVID-19 pandemic, and (2) the nature of health care workers' emotional strain related to the refugee situation and the war in Ukraine.Methods: We used a combination of quantitative regression analyses and qualitative content analysis to assess data collected by an online questionnaire in 2022. The study included 1121 health care workers from the Czech arm of the international HEROES Study.Results: Quantitative findings did not indicate that working with Ukrainian refugees was reliably associated with a greater occurrence of symptoms of depression, anxiety, distress, or burnout. Qualitative analysis revealed five categories of emotional strain: impacts on working conditions, emotional reactions to refugees and the war, comparisons with the COVID-19 pandemic, and coping strategies.Conclusions: This study highlights the resilience of health care workers but also points to the need for ongoing support to address the complex emotional challenges they face during health crises.

Although we did not find a significant association between working with refugees and mental health issues, health professionals encountered emotionally challenging situations.Emotionally challenging situations involved reactions to the war and refugees, worsening working conditions, and higher subjective strain than during the COVID-19 pandemic.When comparing health workers caring for with refugees and COVID-19 patients, we found differences in their mental health issues.

• Klíčová slova
• COVID-19 pandemic, Migración, Migration, Russian-Ukrainian war, emotional strain, guerra ruso-ucraniana, malestar psicológico, pandemia de COVID-19, psychological distress,
• MeSH
• adaptace psychologická MeSH
• COVID-19 * psychologie   MeSH
• deprese psychologie   epidemiologie   MeSH
• dospělí MeSH
• duševní zdraví * MeSH
• lidé středního věku MeSH
• lidé MeSH
• pandemie MeSH
• profesionální vyhoření psychologie   MeSH
• průzkumy a dotazníky MeSH
• psychický stres psychologie   MeSH
• SARS-CoV-2 MeSH
• uprchlíci * psychologie   statistika a číselné údaje   MeSH
• úzkost psychologie   MeSH
• zdravotnický personál * psychologie   statistika a číselné údaje   MeSH
• Check Tag
• dospělí MeSH
• lidé středního věku MeSH
• lidé MeSH
• mužské pohlaví MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• Geografické názvy
• Česká republika MeSH
• Ukrajina MeSH

BACKGROUND: The current negative trend in the physical behavior and lifestyle of the population therefore requires adequate changes in the professional training of physiotherapists. OBJECTIVES: This study aimed to determine the structure and differences in the weekly physical activity (PA) of Czech physiotherapy students, the use of wearables in physiotherapy professional training, and the attitude of physiotherapy students toward PA and the use of wearables in physiotherapy practice. METHODS: Between 2013 and 2022, 412 physiotherapy students participated in a PA-monitoring study using questonnaires International Physical Activity Questionnaire-long form, Motives for Physical Activity Measure-Revise, pedometers, Garmin Vívofit and Axivity AX3 accelerometers. RESULTS: A retrospective analysis of physiotherapy students PA drew attention to insufficient weekly PA and insufficient achievement of the PA recommendation of at least 60 min five times a week (55% of men and 41% of women). Instrumental PA monitoring allowed analyzing individual daily PA and structure of weekly PA. Highest PA indicated men (14,102 steps/day) and women (12,724 steps/day) of the 1st study year on Tuesday. The lowest PA (9,488 steps/day for men and 8,815 steps/day for women), were observed in the 4th study year on Sundays. The recommended target of 11,000 steps per day was achieved by 40% of the men and 46% of the women. Wearables enhanced participants PA motivation (51%). CONCLUSIONS: The inclusion of weekly PA monitoring in the professional training of physiotherapists ensured a deeper insight into the possibilities of PA monitoring in physiotherapy practice . Students are prepared to use wearables more widely to improve physical therapy practice.

The study demonstrated the need for greater support for physical activity (PA) of physiotherapy students during their studies.Incorporating comprehensive weekly PA monitoring into physiotherapy education is essential, especially with the rapid development of wearable technology.Monitoring PA using different methods enabled students to better assess the possibilities of using wearables in physiotherapy practice.

• Klíčová slova
• Physical activity, lifestyle, monitoring, professional education, wearables,
• MeSH
• cvičení * fyziologie   MeSH
• dospělí MeSH
• fyzioterapeuti * výchova   MeSH
• lidé MeSH
• mladý dospělý MeSH
• motivace MeSH
• postoj zdravotnického personálu MeSH
• průzkumy a dotazníky MeSH
• retrospektivní studie MeSH
• Check Tag
• dospělí MeSH
• lidé MeSH
• mladý dospělý MeSH
• mužské pohlaví MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• Geografické názvy
• Česká republika MeSH

BACKGROUND: Venous thromboembolism (VTE) is a frequent complication in critically ill patients, who often have multiple risk factors. Pharmacological thromboprophylaxis is widely applied to lower this risk, but guidelines lack dosing recommendations. OBJECTIVE: This survey aims to assess current thromboprophylaxis preferences and willingness to participate in future randomized clinical trials (RCTs) on this topic. METHOD: We conducted an international online survey between February and May 2023 among intensive care unit (ICU) physicians, including 16 questions about preferences in relation to thromboprophylaxis and preferences on topics for a future RCT. The survey was distributed through the network of the Collaboration for Research in Intensive Care. RESULTS: A total of 715 physicians from 170 ICUs in 23 countries contributed information, with a mean response rate of 36%. In most ICUs, both pharmacological (n = 166, 98%) and mechanical thromboprophylaxis (n = 143, 84%) were applied. A total of 36 pharmacological thromboprophylaxis regimens were reported. Use of low-molecular-weight heparin (LMWH) was most common (n = 149 ICUs, 87%), followed by subcutaneous unfractionated heparin (n = 44 ICUs, 26%). Seventy-five percent of physicians indicated that they used enoxaparin 40 mg (4000 IU), dalteparin 5000 IU, or tinzaparin 4500 IU once daily, whereas 25% reported the use of 16 other LMWH type and dose combinations. Dose adjustment according to weight was common (78 ICUs, 46%). Participants perceived high variation in the application of thromboprophylaxis and were willing to consider an alternative LMWH type (n = 542, 76%) or dose (n = 538, 75%) in the context of an RCT. CONCLUSION: LMWH was the preferred agent for thromboprophylaxis in critically ill patients. There was considerable variation in the application of LMWH for prophylaxis, reflected by the use of different types, doses, and dosing strategies. Most physicians would be willing to participate in an RCT on thromboprophylaxis. EDITORIAL COMMENT: This survey demonstrates current patterns in implementation preferences for critically ill patients. While there is one approach and drug that is commonly preferred, these findings show that there is some variation in practice.

• Klíčová slova
• ICU, survey, thromboprophylaxis,
• MeSH
• antikoagulancia * terapeutické užití   aplikace a dávkování   MeSH
• heparin nízkomolekulární * terapeutické užití   aplikace a dávkování   MeSH
• internacionalita MeSH
• jednotky intenzivní péče * MeSH
• kritický stav MeSH
• lékaři MeSH
• lidé MeSH
• péče o pacienty v kritickém stavu metody   MeSH
• průzkumy a dotazníky MeSH
• žilní tromboembolie * prevence a kontrola   MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• časopisecké články MeSH
• Názvy látek
• antikoagulancia * MeSH
• heparin nízkomolekulární * MeSH

Health care provider payment schemes consist of a complex set of arrangements used to influence provider behavior towards specific health policy objectives. The study aimed at: 1) providing a structured, comparative overview of current payment schemes within the public health system in selected Central and Eastern European (CEE) countries for different health care providers; 2) identifying and comparing major changes in payment schemes since 2010. Methods included: 1) data collection form development; 2) desk research; 3) national experts' consultations; 4) comparative analysis. The results indicate that the nine CEE countries (Bulgaria, Croatia, Czechia, Estonia, Latvia, Lithuania, Hungary, Poland, and Romania) show numerous similarities in provider payment method mix and in the general direction of the recent changes conducted in this field. Output-based payment methods prevail across all countries and types of providers. Primary health care (PHC) providers are characterized by the most diverse payment method mix. PHC and hospital inpatient care have experienced the most frequent changes in their payment schemes within the last 13 years. These focused mostly on modifying existing payment methods (e.g. detailing payment categories), and applying additional methods to pay for specific services or performance (e.g. fee-for-service, bonus payments). The objectives of conducted change were often similar, thus, there is high potential for a shared, cross-country learning.

• Klíčová slova
• Central and Eastern Europe, Health care provider, Provider payment method, Provider payment scheme,
• MeSH
• dávkové mechanismy * MeSH
• lidé MeSH
• primární zdravotní péče ekonomika   MeSH
• zdravotní politika MeSH
• zdravotnický personál MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• časopisecké články MeSH
• přehledy MeSH
• srovnávací studie MeSH
• Geografické názvy
• Česká republika MeSH
• Chorvatsko MeSH
• Estonsko MeSH
• Evropa MeSH
• Litva MeSH
• Lotyšsko MeSH
• Maďarsko MeSH
• Polsko MeSH
• Rumunsko MeSH
• východní Evropa MeSH

Acute intoxications with medications in children and the role of pharmacist in the National toxicological information center National Toxicological Information Center (NTIC) provides 24 hours telephone consultation service in acute intoxications for physicians, health care providers and general public. More than half of all consulted intoxications provided by NTIC belong to the group of children younger than 18 years old. Children 3 years old and younger were the main group of consulted intoxications in all children. Intoxications in children with the age up to 5 years old are often accidental intoxications without any or only mild symptoms. Older children and adolescents are more often consulted due to the suicidal attempt with moderate or severe symptoms. Chemicals, medications and plants were the most often consulted in children aged up to 18-years old during period 2018-2022. Pharmacist has complex knowledge of various scientific disciplines. Pharmacist is valuable health care provider in NTIC as well as in various sectors of health care in society.

• Klíčová slova
• child, diet, intoxication, medication, pharmacist.,
• MeSH
• dítě MeSH
• farmaceuti * MeSH
• informační střediska MeSH
• kojenec MeSH
• lidé MeSH
• mladiství MeSH
• otrava * MeSH
• předškolní dítě MeSH
• role odborníka MeSH
• toxikologická centra * statistika a číselné údaje   MeSH
• Check Tag
• dítě MeSH
• kojenec MeSH
• lidé MeSH
• mladiství MeSH
• předškolní dítě MeSH
• Publikační typ
• časopisecké články MeSH

Available diagnostic tests in the pharmacy and the role of the pharmacist The topic of in vitro diagnostic tests is a relatively robust area of medical devices. It includes tests used in the providing of healthcare, i.e., intended for healthcare professionals, and a group of tests intended directly for consumers (Direct-To-Consumer tests). The subject of the following article is diagnostic tests intended for home in vitro self-testing of patients in the Czech Republic. The aim is to present a basic overview of the available tests, to present the principle of diagnostic tests and in selected groups of tests to summarise the most important information for the correct performance of tests that should be part of pharmaceutical care.

• Klíčová slova
• Pharmaceutical Care, diagnostic device, self-testing.,
• MeSH
• diagnostické testy rutinní * MeSH
• farmaceuti * MeSH
• farmaceutické služby MeSH
• lidé MeSH
• role odborníka * MeSH
• samotestování MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• časopisecké články MeSH
• přehledy MeSH
• Geografické názvy
• Česká republika MeSH

BACKGROUND: The decrease in the number of healthcare workers and the resulting deterioration in healthcare quality and availability have been subjected to intensive discussion in Czechia in recent years. Estimating future healthcare worker capacities requires a detailed analysis of their "movement" within the healthcare system. This study focuses on exits of the primary care physicians from the healthcare system in Czechia. METHODS: Using anonymised data obtained from the largest Czech health insurance company (2012-2022), we constructed working life tables and calculated working life expectancy, which indicates the expected average number of remaining years of work at the exact age of the physician. The study focuses on primary care physicians, who are crucial for the effective functioning of the healthcare system. RESULTS: At age 50, working life expectancy was 20 years for female physicians and approximately 21 years for male physicians. Over the monitored period, working life expectancy decreased by 1 year for both genders. Gynaecologists had the longest working life expectancy, while dentists had the shortest. CONCLUSIONS: The decrease in the working life expectancy and the length of tenure indicates the need to create favourable conditions for the extension of the working lives of physicians to avoid early exits from the system.

• Klíčová slova
• Czechia, Healthcare system, Life tables, Primary care physicians, Working life expectancy,
• MeSH
• dospělí MeSH
• lékaři primární péče * MeSH
• lidé středního věku MeSH
• lidé MeSH
• naděje dožití * MeSH
• primární zdravotní péče MeSH
• zaměstnanost statistika a číselné údaje   MeSH
• zubní lékaři statistika a číselné údaje   MeSH
• Check Tag
• dospělí MeSH
• lidé středního věku MeSH
• lidé MeSH
• mužské pohlaví MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• Geografické názvy
• Česká republika MeSH

UNLABELLED: Safety of injectable dosage forms during their preparation and administration by nurses in hospitals: a literature review Introduction and Aim: Medication errors in hospitals are still frequent and significant for patient safety and associated healthcare costs. Especially, injectable dosage forms pose the high risk. The aim of this study was to review the current literature focused on medication errors related to injectable drug forms during their preparation and administration by nurses in hospitals. METHODS: Databases Medline and Scopus were used for the literature review. Papers dealing with intravenous (i. v.), intramuscular (i. m.), or subcutaneous (s. c.) administration by nurses in hospitals using direct observation method for data collection were searched. Original papers, systematic reviews or meta-analyses published in English by the end of 2022 were included. RESULTS: A total of 334 papers were retrieved, of which 21 studies met the inclusion criteria. 17 studies were observational (8 descriptive, 9 analytical) and 4 interventional. Medication errors were very common, moreover, critical steps of the medication process and possible interventions were identified. CONCLUSION: The results showed that the process of preparing and administering injectable dosage forms is a high-risk process. In the provision of healthcare, relevant measures must be set up to maximise patient safety.

• Klíčová slova
• medication error, nursing staff, hospital, parenteral administration, intravenous administra-tion, medication error, nursing staff, hospital, parenteral administration, intravenous administra-tion.,
• MeSH
• bezpečnost pacientů MeSH
• injekce * MeSH
• lékové formy MeSH
• lidé MeSH
• medikační omyly * prevence a kontrola   statistika a číselné údaje   MeSH
• personál sesterský nemocniční MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• časopisecké články MeSH
• přehledy MeSH
• Názvy látek
• lékové formy MeSH

UNLABELLED: Direct oral anticoagulants from the perspective of Czech pharmacists - opinions, attitudes, confidence, and patient education during dispensing in a pharmacy Introduction and Aim: Pharmacists play an important role in the management of anticoagulation therapy, therefore good knowledge and confidence in care of patients treated with anticoagulation are essential. The aim of this study was to analyse the opinions and attitudes of pharmacists in the Czech Republic towards direct oral anticoagulants (DOACs), their perception of the benefits and risks of DOACs, and the position of pharmacists in educating patients about the basic principles of DOAC treatment in the context of dispensing these medicines in pharmacies. METHODS: An online anonymous questionnaire survey conducted in 2021 among pharmacists of three specific District Pharmacists Associations of the Czech Chamber of Pharmacy. The questionnaire included 32 open- and closed-ended questions, and questions for reporting of the level of agreement using a Likert scale. Descriptive statistics, parametric and non-parametric tests were used to evaluate the data. RESULTS: A total of 162 pharmacists participated (14% return rate), 139 of whom dispensed medicines in a pharmacy in the last year. Respondents working in pharmacies located in any health centre and in hospital pharmacies reported dispensing DOACs more frequently (p < 0.001). The majority of respondents (73%) felt completely or rather confident in providing expert information regarding DOACs. Higher confidence was associated with respondents working in hospital pharmacies or pharmacies located in health centres (p < 0.05), working in clinical pharmacy wards (p < 0.05) and being more likely to dispense DOACs in the pharmacy (p < 0.001). Higher confidence was related to the areas pharmacists discussed with patients during DOAC dispensing, e.g., reasons for using DOACs or how to administer. CONCLUSION: The frequency of dispensing DOACs, type of pharmacy, and working as clinical pharmacist influenced respondents' confidence towards DOACs. Confidence may have influenced the course of DOAC dispensing in the pharmacy. Consolidating the pharmacist's position in patient education during DOAC treatment and strengthening pharmacists' confidence in dispensing DOACs should be therefore considered.

• Klíčová slova
• pharmacists, DOACs, attitude, opinions, education,
• MeSH
• antikoagulancia * terapeutické užití   MeSH
• aplikace orální MeSH
• farmaceuti * MeSH
• lidé MeSH
• postoj zdravotnického personálu * MeSH
• průzkumy a dotazníky MeSH
• vzdělávání pacientů jako téma * MeSH
• zdraví - znalosti, postoje, praxe MeSH
• Check Tag
• lidé MeSH
• mužské pohlaví MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• Geografické názvy
• Česká republika MeSH
• Názvy látek
• antikoagulancia * MeSH