Nejvíce citovaný článek - PubMed ID 33834427
Development of a set of three real-time loop-mediated isothermal amplification (LAMP) assays for detection of Bacillus anthracis, the causative agent of anthrax
Bacillus anthracis is a causative agent of the highly mortal disease anthrax. This zoonosis is present in nature, but it is also considered one of the most powerful biological warfare agents. A timely diagnosis is necessary for proper therapy and setting of epidemiological countermeasures. Current diagnostic methods should be used in specialized laboratories or medical facilities because there are only a limited number of methods suitable as hand-held assays or even point-of-care tests for detecting B. anthracis or anthrax diagnosis. The lateral flow tests are an exception in this regard, but these tests also have some limitations. Significant progress has been achieved in point-of-care tests for B. anthracis detection and anthrax diagnosis in various biosensors and bioassays. This review focuses on current hand-held and point-of-care tests that can easily prove anthrax or its causative agent outside the context of specialized facilities.
- Klíčová slova
- Aptamer, Bacillus anthracis, bioanalysis, biological warfare agent, biological weapon, chemosensor, field test, hand-held assay, infection.,
- MeSH
- antrax * diagnóza MeSH
- Bacillus anthracis * izolace a purifikace MeSH
- biosenzitivní techniky * metody MeSH
- biotest * metody MeSH
- lidé MeSH
- vyšetření u lůžka MeSH
- zvířata MeSH
- Check Tag
- lidé MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- přehledy MeSH