Today, MXenes and their composites have shown attractive capabilities in numerous fields of electronics, co-catalysis/photocatalysis, sensing/imaging, batteries/supercapacitors, electromagnetic interference (EMI) shielding, tissue engineering/regenerative medicine, drug delivery, cancer theranostics, and soft robotics. In this aspect, MXene-carbon nanotube (CNT) composites have been widely constructed with improved environmental stability, excellent electrical conductivity, and robust mechanical properties, providing great opportunities for designing modern and intelligent systems with diagnostic/therapeutic, electronic, and environmental applications. MXenes with unique architectures, large specific surface areas, ease of functionalization, and high electrical conductivity have been employed for hybridization with CNTs with superb heat conductivity, electrical conductivity, and fascinating mechanical features. However, most of the studies have centered around their electronic, EMI shielding, catalytic, and sensing applications; thus, the need for research on biomedical and diagnostic/therapeutic applications of these materials ought to be given more attention. The photothermal conversion efficiency, selectivity/sensitivity, environmental stability/recyclability, biocompatibility/toxicity, long-term biosafety, stimuli-responsiveness features, and clinical translation studies are among the most crucial research aspects that still need to be comprehensively investigated. Although limited explorations have focused on MXene-CNT composites, future studies should be planned on the optimization of reaction/synthesis conditions, surface functionalization, and toxicological evaluations. Herein, most recent advancements pertaining to the applications of MXene-CNT composites in sensing, catalysis, supercapacitors/batteries, EMI shielding, water treatment/pollutants removal are highlighted, focusing on current trends, challenges, and future outlooks.

• Keywords
• MXenes, carbon nanotubes, catalysis, electromagnetic interference shielding, sensing,
• Publication type
• Journal Article MeSH
• Review MeSH

MXenes with unique mechanical, optical, electronic, and thermal properties along with a specific large surface area for surface functionalization/modification, high electrical conductivity, magnetic properties, biocompatibility, and low toxicity have been explored as attractive candidates for the targeted delivery of drugs in cancer therapy. These two-dimensional materials have garnered much attention in the field of cancer therapy since they have shown suitable photothermal effects, biocompatibility, and luminescence properties. However, outstanding challenging issues regarding their pharmacokinetics, biosafety, targeting properties, optimized functionalization, synthesis/reaction conditions, and clinical translational studies still need to be addressed. Herein, recent advances and upcoming challenges in the design of advanced targeted drug delivery micro- and nanosystems in cancer therapy using MXenes have been discussed to motivate researchers to further investigate this field of science.

• Keywords
• MXene-based systems, cancer nanotherapy, nanocomposites, photothermal therapy, targeted drug delivery,
• Publication type
• Journal Article MeSH
• Review MeSH

These days, explorations have focused on designing two-dimensional (2D) nanomaterials with useful (photo)catalytic and environmental applications. Among them, MXene-based composites have garnered great attention owing to their unique optical, mechanical, thermal, chemical, and electronic properties. Various MXene-based photocatalysts have been inventively constructed for a variety of photocatalytic applications ranging from pollutant degradation to hydrogen evolution. They can be applied as co-catalysts in combination with assorted common photocatalysts such as metal sulfide, metal oxides, metal-organic frameworks, graphene, and graphitic carbon nitride to enhance the function of photocatalytic removal of organic/pharmaceutical pollutants, nitrogen fixation, photocatalytic hydrogen evolution, and carbon dioxide conversion, among others. High electrical conductivity, robust photothermal effects, large surface area, hydrophilicity, and abundant surface functional groups of MXenes render them as attractive candidates for photocatalytic removal of pollutants as well as improvement of photocatalytic performance of semiconductor catalysts. Herein, the most recent developments in photocatalytic degradation of organic and pharmaceutical pollutants using MXene-based composites are deliberated, with a focus on important challenges and future perspectives; techniques for fabrication of these photocatalysts are also covered.

• Keywords
• MXene-based nanocomposites, MXenes, pharmaceutical pollutants, photocatalysis, photocatalytic degradation, pollutants,
• MeSH
• Graphite * chemistry   MeSH
• Environmental Pollutants * chemistry   MeSH
• Pharmaceutical Preparations MeSH
• Carbon Dioxide MeSH
• Oxides MeSH
• Metal-Organic Frameworks * MeSH
• Sulfides MeSH
• Hydrogen MeSH
• Publication type
• Journal Article MeSH
• Review MeSH
• Names of Substances
• Graphite * MeSH
• Environmental Pollutants * MeSH
• Pharmaceutical Preparations MeSH
• Carbon Dioxide MeSH
• Oxides MeSH
• Metal-Organic Frameworks * MeSH
• Sulfides MeSH
• Hydrogen MeSH

MXenes encompass attractive properties such as a large surface area, unique chemical structures, stability, elastic mechanical strength, excellent electrical conductivity, hydrophilicity, and ease of surface functionalization/modifications, which make them one of the broadly explored two-dimensional materials in the world. MXene-based micro- and nanocomposites/systems with special optical, mechanical, electronic, and excellent targeting/selectivity features have been explored for cancer nanotheranostics. These materials exhibit great diagnostic and therapeutic potential and offer opportunities for cancer photoacoustic imaging along with photodynamic and photothermal therapy. They can be applied to targeted anticancer drug delivery while being deployed for the imaging/diagnosis of tumors/cancers and malignancies. MXene-based systems functionalized with suitable biocompatible or bioactive agents have suitable cellular uptake features with transferring potential from vascular endothelial cells and specific localization, high stability, and auto-fluorescence benefits at different emission-excitation wavelengths, permitting post-transport examination and tracking. The surface engineering of MXenes can improve their biocompatibility, targeting, bioavailability, and biodegradability along with their optical, mechanical, and electrochemical features to develop multifunctional systems with cancer theranostic applications. However, challenges still persist in terms of their environmentally benign fabrication, up-scalability, functionality improvement, optimization conditions, surface functionalization, biocompatibility, biodegradability, clinical translational studies, and pharmacokinetics. This manuscript delineates the recent advancements, opportunities, and important challenges pertaining to the cancer nanotheranostic potential of MXenes and their derivatives.

• Keywords
• MXene-based composites, MXenes, cancer diagnostics, cancer therapeutics, nanotheranostics,
• Publication type
• Journal Article MeSH
• Review MeSH