Herein, the recent advances in the development of resorbable polymeric-based biomaterials, their geometrical forms, resorption mechanisms, and their capabilities in various biomedical applications are critically reviewed. A comprehensive discussion of the engineering approaches for the fabrication of polymeric resorbable scaffolds for tissue engineering, drug delivery, surgical, cardiological, aesthetical, dental and cardiovascular applications, are also explained. Furthermore, to understand the internal structures of resorbable scaffolds, representative studies of their evaluation by medical imaging techniques, e.g., cardiac computer tomography, are succinctly highlighted. This approach provides crucial clinical insights which help to improve the materials' suitable and viable characteristics for them to meet the highly restrictive medical requirements. Finally, the aspects of the legal regulations and the associated challenges in translating research into desirable clinical and marketable materials of polymeric-based formulations, are presented.

• Keywords
• clinical challenges, drug delivery, implants, medical imaging, polymer matrices, resorbable biomaterials, tissue engineering,
• MeSH
• Biocompatible Materials chemistry   MeSH
• Drug Delivery Systems * methods   MeSH
• Humans MeSH
• Polymers * chemistry   MeSH
• Tissue Engineering * methods   MeSH
• Tissue Scaffolds chemistry   MeSH
• Absorbable Implants MeSH
• Animals MeSH
• Check Tag
• Humans MeSH
• Animals MeSH
• Publication type
• Journal Article MeSH
• Review MeSH
• Names of Substances
• Biocompatible Materials MeSH
• Polymers * MeSH