Herein, the recent advances in the development of resorbable polymeric-based biomaterials, their geometrical forms, resorption mechanisms, and their capabilities in various biomedical applications are critically reviewed. A comprehensive discussion of the engineering approaches for the fabrication of polymeric resorbable scaffolds for tissue engineering, drug delivery, surgical, cardiological, aesthetical, dental and cardiovascular applications, are also explained. Furthermore, to understand the internal structures of resorbable scaffolds, representative studies of their evaluation by medical imaging techniques, e.g., cardiac computer tomography, are succinctly highlighted. This approach provides crucial clinical insights which help to improve the materials' suitable and viable characteristics for them to meet the highly restrictive medical requirements. Finally, the aspects of the legal regulations and the associated challenges in translating research into desirable clinical and marketable materials of polymeric-based formulations, are presented.

Chemical and Biomedical Engineering Department University of Missouri 1030 Hill Street Columbia Missouri 65211 USA

Department of Cardiology Hospital Clínico San Carlos Madrid Spain

Department of Engineering Science University of Oxford Parks Road Oxford OX1 3PJ UK

Institute of Materials Technology Polymer Division Poznan University of Technology Poznan Poland

Instituto de Investigación Sanitaria del Hospital Clínico San Carlos Madrid Spain

New Technologies Research Centre University of West Bohemia Univerzitní 8 Pilsen 30100 Czech Republic

School of Engineering Newcastle University Newcastle upon Tyne Newcastle NE1 7RU UK

Tshwane University of Technology Department of Chemical Metallurgical and Materials Engineering Polymer Division and Institute for Nano Engineering Research Pretoria West Campus Pretoria South Africa

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