• MeSH
• dějiny 19. století MeSH
• giardiáza dějiny   MeSH
• lidé MeSH
• terminologie jako téma * MeSH
• Check Tag
• dějiny 19. století MeSH
• lidé MeSH
• Publikační typ
• biografie MeSH
• dopisy MeSH
• historické články MeSH
• Geografické názvy
• Československo MeSH

• O autorovi
• Lambl, V D

A group of 118 patients, aged 1-73 years, suffering from giardiasis in their gastrointestinal tract was studied in the period of 1988-1990. The analysis consisted in determination of frequency, sex distribution, age categories and incidence within the period of 12 months. Patients older than 15 years were asked about the possible sources of infection, subjective and objective symptoms and therapy. The information obtained for our region were compared with data reported in literature.

• MeSH
• dítě MeSH
• dospělí MeSH
• giardiáza epidemiologie   patofyziologie   MeSH
• incidence MeSH
• lidé středního věku MeSH
• lidé MeSH
• mladiství MeSH
• senioři MeSH
• Check Tag
• dítě MeSH
• dospělí MeSH
• lidé středního věku MeSH
• lidé MeSH
• mladiství MeSH
• mužské pohlaví MeSH
• senioři MeSH
• ženské pohlaví MeSH
• Publikační typ
• anglický abstrakt MeSH
• časopisecké články MeSH
• Geografické názvy
• Československo epidemiologie   MeSH

The relationship between giardiasis and ABO blood groups was studied in a group of 136 children from Eastern Slovakia, with a special attention to ethnic specifics of gipsy children. The study showed no statistically significant differences in the distribution of ABO blood groups between the subgroup of Giardia-infected gipsy children and the gipsy population minority living in the area. On the other hand, the ABO distribution pattern in subgroup of non-gipsy children infected with Giardia intestinalis was found to differ from that in the general non-gipsy Eastern Slovakian population by the absence of blood group AB among children with giardiasis. There was indicated a tendency towards an increased frequency of blood group B in subgroup of Giardia-infected gipsy children and towards group A in subgroup of nongipsy children with giardiasis, but the differences were not statistically significant.

• MeSH
• ABO systém krevních skupin * MeSH
• dítě MeSH
• etnicita MeSH
• giardiáza krev   epidemiologie   MeSH
• lidé MeSH
• Romové MeSH
• Check Tag
• dítě MeSH
• lidé MeSH
• Publikační typ
• časopisecké články MeSH
• Geografické názvy
• Československo MeSH
• Názvy látek
• ABO systém krevních skupin * MeSH

Here, we report a case of direct zoonotic transmission of giardiasis between a pet chinchilla and a human. Microscopic and molecular examinations of stool samples from a child and samples of chinchilla droppings revealed cysts/DNA of Giardia intestinalis. The transmission from the chinchilla to the child has been confirmed as coprophagous after the 1-year-old toddler ingested pet chinchilla droppings. Molecular analysis of the gdh gene from both hosts classified the G. intestinalis cysts into the assemblage B genetic group, which has been previously shown to be characteristic of both human and chinchilla giardiasis. Both Giardia sub-assemblages BIII and BIV were present in the chinchilla droppings, whereas only the sub-assemblage BIV was isolated from the child's stool sample. To the best of our knowledge, this is the first report of a true zoonotic transmission of giardiasis, supporting the zoonotic potential of assemblage B.

• Klíčová slova
• Assemblage B, Chinchilla, Giardia intestinalis, Zoonotic giardiasis,
• MeSH
• činčila * MeSH
• domácí zvířata * MeSH
• feces parazitologie   MeSH
• Giardia lamblia izolace a purifikace   MeSH
• giardiáza parazitologie   přenos   veterinární   MeSH
• kojenec MeSH
• koprofagie etiologie   MeSH
• lidé MeSH
• nemoci hlodavců parazitologie   přenos   MeSH
• zoonózy parazitologie   přenos   MeSH
• zvířata MeSH
• Check Tag
• kojenec MeSH
• lidé MeSH
• mužské pohlaví MeSH
• zvířata MeSH
• Publikační typ
• časopisecké články MeSH
• kazuistiky MeSH

Fifteen Mongolian gerbils were inoculated with 10 × 106 viable trophozoites of Giardia intestinalis. Their faeces were examined daily by flotation method and the number of shed cysts was counted. Two animals (male and female) were euthanised at 4- to 5-day intervals (9, 14, 18 days post-infection (DPI)). The remaining nine gerbils were sacrificed and dissected at the end of the experiment (23 DPI). Their small intestinal tissues were processed for examination using histological sectioning and scanning electron microscopy and their complete blood count (CBC) was examined. The highest number of trophozoites at the total was observed in the duodenum in gerbils sacrificed on 14 DPI. Number of shed cysts was positively correlated with number of trophozoites rinsed from the intestine. Infected gerbils had lower body weight gain in comparison with control group and in three male gerbils; diarrhoea occurred during infection. Cyst shedding was negatively correlated with values of mean corpuscular haemoglobin concentration. Females showed another pattern in cyst shedding than males. This information needs to be taken into account while planning the experiments.

• Klíčová slova
• Gerbil model, Giardia intestinalis, Giardial intestinal distribution, Giardiasis,
• MeSH
• duodenum parazitologie   patologie   MeSH
• feces parazitologie   MeSH
• Gerbillinae * parazitologie   MeSH
• Giardia lamblia růst a vývoj   fyziologie   MeSH
• giardiáza parazitologie   patologie   MeSH
• lidé MeSH
• mikroskopie elektronová rastrovací MeSH
• modely nemocí na zvířatech MeSH
• trofozoiti růst a vývoj   fyziologie   MeSH
• zvířata MeSH
• Check Tag
• lidé MeSH
• mužské pohlaví MeSH
• ženské pohlaví MeSH
• zvířata MeSH
• Publikační typ
• časopisecké články MeSH

Mean nitrate content in the morning urine of 117 patients with giardiasis comprises 155.3 mg/l, which exceeds about 4 fold the normal value. Maximum concentrations of 1000 mg/l were observed. Under treatment with metronidazol (Vagimid) nitrate content at first increased and then restored to normal. Endogenously synthesized nitrate with giardiasis 3-4 fold exceeds the daily nitrate intake by food and, therefore, plays an important role in total nitrate load of the patients.

• MeSH
• dospělí MeSH
• dusitany moč   MeSH
• feces parazitologie   MeSH
• Giardia izolace a purifikace   MeSH
• giardiáza farmakoterapie   moč   MeSH
• kojenec MeSH
• lidé MeSH
• metronidazol terapeutické užití   MeSH
• premedikace MeSH
• těhotenství MeSH
• zvířata MeSH
• Check Tag
• dospělí MeSH
• kojenec MeSH
• lidé MeSH
• mužské pohlaví MeSH
• těhotenství MeSH
• ženské pohlaví MeSH
• zvířata MeSH
• Publikační typ
• časopisecké články MeSH
• Názvy látek
• dusitany MeSH
• metronidazol MeSH

The clinical, pathological and parasitological features of giardiasis resulting from experimental inoculation with 3 x 10(6) Giardia cysts were studied in goat kids. All experimentally inoculated goat kids given Giardia cysts became infected. Three of the eight inoculated kids had decreased appetite, formless feces and become slightly depressed beginning 7 or 8 days post inoculation. The mean duration of the appearance of abnormal feces was 6 days. Irregular and intermitted cysts shedding started after prepatent periods of 6-10 days and lasted throughout this study (10 weeks). The evidence of high infectivity and fast transmission of Giardia were observed under standard zoohygienic conditions. The characteristics of intestinal lesions were similar to those found in other hosts infected with Giardia. The most severe lesions were seen in the duodenum and proximal jejunum, and consisted of moderate villus atrophy, villus blunting, crypt hyperplasia and inflammatory infiltration in the lamina propria. Scanning electron microscopy revealed ultrastructural alterations in the microvillus border of enterocytes. Mucosal smears and histological sections of the gall bladder displayed Giardia trophozoites and gall bladder epithelium hyperplasia together with bile ductular proliferation in the liver tissue in two kids.

• MeSH
• feces parazitologie   MeSH
• Gerbillinae MeSH
• Giardia izolace a purifikace   MeSH
• giardiáza patologie   patofyziologie   veterinární   MeSH
• jejunum parazitologie   MeSH
• kozy MeSH
• mikroklky patologie   ultrastruktura   MeSH
• mikroskopie elektronová rastrovací MeSH
• nemoci koz * MeSH
• nemoci prasat MeSH
• prasata MeSH
• střevní sliznice parazitologie   patologie   ultrastruktura   MeSH
• zvířata MeSH
• Check Tag
• mužské pohlaví MeSH
• ženské pohlaví MeSH
• zvířata MeSH
• Publikační typ
• časopisecké články MeSH
• práce podpořená grantem MeSH

The authors hospitalized and treated in 1990-1994 at their Clinic 127 patients where giardiasis was the main or secondary diagnosis. They wanted to draw attention to the increasing prevalence of the disease, to clinical manifestations and problems associated with treatment. Clinicians should consider the possible presence of this disease in different gastrointestinal manifestations, chronic hepatitis, hepatopathies as well as in acute IgM anti-HAV, HBsAg and HCV negative hepatitis.

• MeSH
• giardiáza diagnóza   terapie   MeSH
• lidé MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• anglický abstrakt MeSH
• časopisecké články MeSH

• MeSH
• giardiáza * diagnóza   terapie   MeSH
• lidé MeSH
• parazitární nemoci střev * diagnóza   terapie   MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• časopisecké články MeSH

In subjects with positive giardiasis tests examinations of contacts were made not only in all members of the family but also in dogs and cats living with them in the same household. Attention was paid to the possible transmission of giardias. A total of 174 families were examined, i.e. 1140 subjects incl. 156 positive ones. Of 123 examined dogs 9 were positive and of 56 cats 8 were positive. Forty-three dog keepers were negative, of their 222 dogs 60 were positive. Although no association was proved between the infection of domestic animals and humans in the examined group, it is recommended to treat not only humans but also domestic animals.

• MeSH
• Giardia izolace a purifikace   MeSH
• giardiáza přenos   MeSH
• kočky parazitologie   MeSH
• lidé MeSH
• psi parazitologie   MeSH
• zoonózy * MeSH
• zvířata MeSH
• Check Tag
• kočky parazitologie   MeSH
• lidé MeSH
• psi parazitologie   MeSH
• zvířata MeSH
• Publikační typ
• anglický abstrakt MeSH
• časopisecké články MeSH