• MeSH
• metody MeSH
• monitorování fyziologických funkcí * MeSH
• oxymetrie * MeSH
• psi MeSH
• spotřeba kyslíku MeSH
• techniky in vitro MeSH
• zvířata MeSH
• Check Tag
• psi MeSH
• zvířata MeSH
• Publikační typ
• časopisecké články MeSH

Head-up tilt table testing is used for diagnostics of vasovagal syncope. Beat-to-beat blood pressure recording and ECG monitoring is not sufficient for clarification of the syncope mechanisms in individual patients, however. That is why a Task Force Monitor was developed in Graz, Austria. In addition this device enables stroke volume recording by impedance method. Other advantages are calculations of cardiac output, beat-to-beat total peripheral resistance, heart rate variability and baroreflex sensitivity as well as activity ofsympathicus and parasympathicus assessment. These methods enable detailed hemodynamic analysis during the whole head-up tilt testing duration, the moment of syncope including.

• MeSH
• baroreflex MeSH
• hemodynamika * MeSH
• lidé MeSH
• monitorování fyziologických funkcí přístrojové vybavení   MeSH
• test na nakloněné rovině * MeSH
• vazovagální synkopa diagnóza   patofyziologie   MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• anglický abstrakt MeSH
• časopisecké články MeSH

INTRODUCTION: We conducted this study to show the safety and efficacy of a new implantable cardiac monitor (ICM), the BioMonitor 2 (Biotronik SE & Co. KG; Berlin, Germany), and to describe the arrhythmia detection performance. METHODS: The BioMonitor 2 has an extended sensing vector and is implanted close to the heart. It can transmit up to six subcutaneous electrocardiogram strips by Home Monitoring each day. We enrolled 92 patients with a standard device indication for an ICM in a single-arm, multicenter prospective trial. Patients were followed for 3 months, and 48-h Holter recordings were used to evaluate the arrhythmia detection performance. RESULTS: One patient withdrew consent and in one patient, the implantation failed. Two study device-related serious adverse events were reported, satisfying the primary safety hypothesis. Implantations took 7.4 ± 4.4 min from skin cut to suture. At 1 week, the R-wave amplitude was 0.75 ± 0.53 mV. In the 82 patients with completed Holter recordings, all patients with arrhythmias were correctly identified. False positive detections of arrhythmia were mostly irregular rhythms wrongly detected as atrial fibrillation (episode-based positive predictive value 72.5%). Daily Home Monitoring transmission was 94.9% successful. CONCLUSION: Safety and efficacy of the new device has been demonstrated. The detected R-wave amplitudes are large, leading to a low level of inappropriate detections due to over- or undersensing.

• Klíčová slova
• arrhythmia detection, atrial fibrillation, implantable cardiac monitor, remote monitoring, syncope,
• MeSH
• design vybavení MeSH
• elektrokardiografie ambulantní přístrojové vybavení   MeSH
• lidé středního věku MeSH
• lidé MeSH
• prospektivní studie MeSH
• srdeční arytmie diagnóza   MeSH
• Check Tag
• lidé středního věku MeSH
• lidé MeSH
• mužské pohlaví MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• hodnotící studie MeSH
• multicentrická studie MeSH

• MeSH
• lidé MeSH
• novorozenec MeSH
• registrace * MeSH
• vrozené vady epidemiologie   MeSH
• Check Tag
• lidé MeSH
• novorozenec MeSH
• Publikační typ
• anglický abstrakt MeSH
• časopisecké články MeSH
• Geografické názvy
• Československo MeSH

• Klíčová slova
• FETAL HEART *, LABOR *,
• MeSH
• fetální srdce * MeSH
• komplexní směsi MeSH
• lidé MeSH
• monitorování plodu * MeSH
• porodní děj * MeSH
• těhotenství MeSH
• Check Tag
• lidé MeSH
• těhotenství MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• Názvy látek
• komplexní směsi MeSH
• Prema MeSH Prohlížeč

The Vasotrac monitor provides non-invasive near-continuous blood pressure monitoring and is designed to be an alternative to direct intra-arterial blood pressure (BP) measurement. As compared to radial artery invasive BP and upper arm non-invasive BP, Vasotrac readings have been found to have a good agreement with them. However, discrepancies have been reported when rapid changes in BP exist. In the present study we compared BP measured by the Vasotrac monitor on the radial artery with that recorded on the finger arteries by the differential oscillometric device allowing measurement on the beat-to-beat basis. Comparisons were performed on the mean arterial pressure (MAP) level. Special attention was paid to the signal conditioning before comparison of pressures of different temporal resolution. Altogether 383 paired MAP measurements were made in 14 healthy subjects. Based on all 383 paired measurements, the MAP values measured at the radial artery at rest were 4.8+/-6.0 mm Hg higher than those measured on fingers. The observed difference between the Vasotrac and differential oscillometric device can be explained by different measurement sites. This result is consistent with previous investigations, and the Vasotrac monitor can be considered to adequately track relatively rapid MAP changes on the radial artery. Attention should be paid to a proper signal conditioning before comparison of results obtained by different devices.

• MeSH
• arteria radialis fyziologie   MeSH
• lidé MeSH
• měření krevního tlaku přístrojové vybavení   metody   MeSH
• mladý dospělý MeSH
• monitorování fyziologických funkcí přístrojové vybavení   metody   MeSH
• oscilometrie přístrojové vybavení   metody   MeSH
• prsty ruky krevní zásobení   MeSH
• Check Tag
• lidé MeSH
• mladý dospělý MeSH
• mužské pohlaví MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• klinické zkoušky MeSH
• práce podpořená grantem MeSH
• srovnávací studie MeSH

• MeSH
• lidé MeSH
• registrace * MeSH
• sběr dat MeSH
• vrozené vady epidemiologie   MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• anglický abstrakt MeSH
• časopisecké články MeSH
• Geografické názvy
• Československo MeSH

This paper presents a newly-designed and realized Invasive Blood Pressure (IBP) device for the simulation on patient's monitors. This device shows improvements and presents extended features with respect to a first prototype presented by the authors and similar systems available in the state-of-the-art. A peculiarity of the presented device is that all implemented features can be customized from the developer and from the point of view of the end user. The realized device has been tested, and its performances in terms of accuracy and of the back-loop measurement of the output for the blood pressure regulation utilization have been described. In particular, an accuracy of ±1 mmHg at 25 °C, on a range from -30 to 300 mmHg, was evaluated under different test conditions. The designed device is an ideal tool for testing IBP modules, for zero setting, and for calibrations. The implemented extended features, like the generation of custom waveforms and the Universal Serial Bus (USB) connectivity, allow use of this device in a wide range of applications, from research to equipment maintenance in clinical environments to educational purposes. Moreover, the presented device represents an innovation, both in terms of technology and methodologies: It allows quick and efficient tests to verify the proper functioning of IBP module of patients' monitors. With this innovative device, tests can be performed directly in the field and faster procedures can be implemented by the clinical maintenance personnel. This device is an open source project and all materials, hardware, and software are fully available for interested developers or researchers.

• Klíčová slova
• exciter voltage, invasive blood pressure, medical devices, waveform simulation,
• MeSH
• design vybavení MeSH
• kalibrace MeSH
• krevní tlak fyziologie   MeSH
• lidé MeSH
• měření krevního tlaku přístrojové vybavení   metody   MeSH
• monitorování fyziologických funkcí přístrojové vybavení   metody   MeSH
• monitory krevního tlaku * MeSH
• software MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• časopisecké články MeSH

Tributyltin (TBT) contamination remains a major problem worldwide. Many laboratories are committed to the development of remediation methodologies that could help reduce the negative impact of this compound in the environment. Furthermore, it is important to have at hand simple methodologies for evaluating TBT toxicity in the laboratory, besides the use of complex and costly analytical instrumentation. With that purpose, a method was adapted that is based on the inhibition of growth of an indicator strain, Micrococcus luteus ATCC 9341, under TBT. Different types of matrices, of TBT concentrations and sample treatments were tested. The results herein reported show that the bioassay method can be applied for both aqueous and soil samples and also for a high range of TBT concentrations (at least up to 500 μmol/L). Besides being cheap and easy to perform, it can be performed in any laboratory. Additionally, one possible application of the method to monitor TBT degradation is presented as an example.

• MeSH
• časové faktory MeSH
• Micrococcus luteus účinky léků   MeSH
• mikrobiální testy citlivosti metody   MeSH
• monitorování životního prostředí metody   MeSH
• trialkylcínové sloučeniny toxicita   MeSH
• Publikační typ
• časopisecké články MeSH
• práce podpořená grantem MeSH
• Názvy látek
• trialkylcínové sloučeniny MeSH
• tributyltin MeSH Prohlížeč

Land-use regression (LUR) models provide location and time specific estimates of exposure to air pollution and thereby improve the sensitivity of health effects models. However, they require pollutant concentrations at multiple locations along with land-use variables. Often, monitoring is performed over short durations using mobile monitoring with research-grade instruments. Low-cost PM monitors provide an alternative approach that increases the spatial and temporal resolution of the air quality data. LUR models were developed to predict hourly PM concentrations across a metropolitan area using PM concentrations measured simultaneously at multiple locations with low-cost monitors. Monitors were placed at 23 sites during the 2015/16 heating season. Monitors were externally calibrated using co-located measurements including a reference instrument (GRIMM particle spectrometer). LUR models for each hour of the day and weekdays/weekend days were developed using the deletion/substitution/addition algorithm. Coefficients of determination for hourly PM predictions ranged from 0.66 and 0.76 (average 0.7). The hourly-resolved LUR model results will be used in epidemiological studies to examine if and how quickly, increases in ambient PM concentrations trigger adverse health events by reducing the exposure misclassification that arises from using less time resolved exposure estimates.

• Klíčová slova
• Exposure assessment, Land-use regression, Low-cost monitors, PM(2.5),
• MeSH
• látky znečišťující vzduch * MeSH
• monitorování životního prostředí * přístrojové vybavení   metody   MeSH
• pevné částice MeSH
• roční období MeSH
• teoretické modely MeSH
• znečištění ovzduší * MeSH
• Publikační typ
• časopisecké články MeSH
• práce podpořená grantem MeSH
• Názvy látek
• látky znečišťující vzduch * MeSH
• pevné částice MeSH