A 68-year-old man with severe craniofacial trauma underwent endoscopic surgery for nasal cerebrospinal fluid leak. During the operation, a plastic object in the shape of a spectacle lens was found wedged in the left nasal passage, which we extracted. As subsequently established from the patient's documentation, it was a dislodged acrylic implant originally placed at the base of the orbit which was surgically treated after an injury to the facial skeleton thirty-five years ago. What is also rare about this is the fact that the patient had been examined for many years at the otorhinology department for purulent discharge from the left nasal cavity and impaired ventilation. The patient had also undergone an endoscopic examination of the nasal cavity during which an intranasal tumor was even suspected, but it was not histologically confirmed.

• Klíčová slova
• craniofascial injury, endoscopy, intranasal foreing object,
• MeSH
• cizí tělesa * komplikace   diagnostické zobrazování   chirurgie   MeSH
• endoskopie MeSH
• lidé MeSH
• nosní dutina * chirurgie   MeSH
• senioři MeSH
• únik mozkomíšního moku MeSH
• Check Tag
• lidé MeSH
• mužské pohlaví MeSH
• senioři MeSH
• Publikační typ
• časopisecké články MeSH
• kazuistiky MeSH

• Klíčová slova
• NASAL CAVITY *, TEETH, DECIDUOUS *,
• MeSH
• lidé MeSH
• nosní dutina * MeSH
• paranazální dutiny * MeSH
• zuby mléčné * MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• časopisecké články MeSH

• Klíčová slova
• NASAL CAVITY/neoplasms *, NEUROBLASTOMA *,
• MeSH
• lidé MeSH
• nádory * MeSH
• neuroblastom * MeSH
• nosní dutina * MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• časopisecké články MeSH

Respiratory epithelial adenomatoid hamartoma (REAH) is relatively new diagnosis, firstly described in WHO tumour classification in 2005. It is a benign lesion affecting nose and paranasal sinuses. Although REAH was considered a rare entity, it is recently more frequently revealed in histopathological exam in patients undergoing endoscopic surgery for nasal polyposis. There have been so far operated two patients with diagnosis of REAH in our department. Both were solitary lesions, and both were resected endoscopically. Definitive histopathological examination confirmed the finding of preoperative biopsy under local anesthesia. No recurrent disease has been observed. Considering quite frequent occurrence of REAH in patients with nasal polyposis and low awareness of the disease itself among ENT specialists, pathologists and radiologists it is still relatively underdiagnosed lesion. The possibility of misdiagnosis and confusion with other more serious diseases like inverted papilloma or low-grade adenocarcinoma is of clinical importance. It may lead to overtreatment and too aggressive surgical therapy.

• Klíčová slova
• benign sinonasal lesion, endoscopic endonasal surgery, respiratory epithelial adenomatoid hamartoma,
• MeSH
• diferenciální diagnóza MeSH
• endoskopie MeSH
• hamartom * MeSH
• lidé MeSH
• nosní dutina MeSH
• nosní polypy * MeSH
• paranazální dutiny * MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• časopisecké články MeSH

The activities of some enzymes were described in the developing human nasal cavity in relatively early stages. In cryostat sections of the 8-14-week-old fetuses processed by standard Lojda methods, activities of the following enzymes were found in the respiratory and olfactory regions: ALP, ACP, ATP, TPP, alpha-GPDH, G6PDH, SDH and ANE. The positive reaction for DPP IV failed to be proved in this localization, it was not detected even in the capillary bed of the nasal cavity.

• MeSH
• fosfatasy metabolismus   MeSH
• histocytochemie MeSH
• lidé MeSH
• nosní sliznice embryologie   enzymologie   MeSH
• oxidoreduktasy metabolismus   MeSH
• plod enzymologie   MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• časopisecké články MeSH
• Názvy látek
• fosfatasy MeSH
• oxidoreduktasy MeSH

BACKGROUNDS: Mucoepidermoid tumours arise from the ductal cells of the salivary glands, most commonly the parotid. The occurrence of these tumours in the mucus glands of the air passages is extremely rare. They are very aggressive tumours with poor prognosis. CASE: A case of nasal mucoepidermoid carcinoma with probable origin from the middle turbinate is reported. CONCLUSION: Nasal mucoepidermoid carcinomas are extremely rare. They usually present with symptoms similar to sinusitis. When dealing with a recurrent/aggressive tumour in the ethmoids, the possibility of mucoepidermoid carcinoma can be considered in the differential diagnosis. They are aggressive tumours with a poor prognosis.

• MeSH
• lidé středního věku MeSH
• lidé MeSH
• magnetická rezonanční tomografie MeSH
• mukoepidermoidní karcinom diagnóza   MeSH
• nádory nosu diagnóza   MeSH
• nosní dutina * MeSH
• počítačová rentgenová tomografie MeSH
• Check Tag
• lidé středního věku MeSH
• lidé MeSH
• mužské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• kazuistiky MeSH

• MeSH
• elektronová mikroskopie MeSH
• embryo savčí anatomie a histologie   ultrastruktura   MeSH
• ježkovití anatomie a histologie   MeSH
• mikroskopie MeSH
• nosní dutina anatomie a histologie   MeSH
• nosní sliznice ultrastruktura   MeSH
• zvířata MeSH
• Check Tag
• mužské pohlaví MeSH
• ženské pohlaví MeSH
• zvířata MeSH
• Publikační typ
• časopisecké články MeSH

INTRODUCTION: Impacted mesiodentes in the inverted position may interfere with the base of the nasal cavity or the nasal septum. They can rarely erupt into the nose as well. Traditionally they are extracted via intraoral approaches (transpalatal or vestibular). Also, an endoscopically assisted transnasal approach can be used. In this paper, the authors are the first to present a group of patients suffering from impacted mesiodentes who have been surgically treated using a modified maxillary vestibular approach with subperiostal intranasal dissection. MATERIAL AND METHOD: The prospective study was completed in the time period 12/2013-6/2017. The inclusion criteria were: 1. Mesiodens impacted in the inverted position extending to the base of the nasal cavity or into the nasal septum without concomitant pathological lesion and without eruption into the nasal cavity. 2. Localization of the mesiodens at the level of or dorsally to the roots of the upper middle incisors in the sagittal plane or ventrally to the roots of these teeth, but with the crown extending significantly posteriorly to the base of the nasal cavity.3. Indication for extraction because of clinical or orthodontic reasons. RESULTS: In total, 9 patients were enrolled into the group. In these patients, surgical extractions of 9 mesiodentes were performed using the alternative approach described above. All extractions were done according to a uniform surgical protocol. The mean age of the patients was 11.7 ± 3.1 years (age range 7-17 years). The crown's most cranial point exceeded the bone of the nasal cavity on average by2.0 ± 1.4 mm (in the range 0-5 mm). 8 mesiodentes were conical, 1 was tuberculate. Surgical procedure and postoperative healing were always without any complications. CONCLUSION: For the removal of midline supernumerary teeth, the modified maxillary vestibular approach with subperiostal intranasal dissection in comparison to the intraoral palatal approach provides less postoperative morbidity and a lower risk of complications (smaller surgical wound, minimal exposure of maxilla, minimal bone loss, reduced risk of damage to the roots of the upper incisors, lower risk of damage to the nasopalatine neurovascular bundle, good visibility in the surgical field, easier surgery, and finally no need of postoperative palatal splint). For oral and maxillofacial surgeons the presented technique represents a more traditional way of surgical tooth extraction than the endoscopically assisted transnasal approach.

• Klíčová slova
• Mesiodens, Modified maxillary vestibular approach, Supernumerary tooth, Surgical extraction, Tooth impaction in the nasal floor,
• MeSH
• disekce metody   MeSH
• dítě MeSH
• extrakce zubů metody   MeSH
• lidé MeSH
• malokluze etiologie   terapie   MeSH
• maxila chirurgie   MeSH
• mladiství MeSH
• nosní dutina patologie   chirurgie   MeSH
• ortodoncie korekční metody   MeSH
• prospektivní studie MeSH
• řezáky abnormality   diagnostické zobrazování   chirurgie   MeSH
• zaklíněný zub diagnostické zobrazování   chirurgie   terapie   MeSH
• zuby přespočetné komplikace   diagnostické zobrazování   patologie   chirurgie   MeSH
• Check Tag
• dítě MeSH
• lidé MeSH
• mladiství MeSH
• mužské pohlaví MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH

Angiofibromas are rare vascular tumors which originate predominantly in the nasopharynx and occur typically in male adolescents. Extranasopharyngeal sites such as nasal cavity and paranasal sinuses are less frequent. This review article was undertaken to evaluate the incidence, clinical features and management of extranasopharyngeal angiofibromas originating exclusivelly from nasal cavity structures. Our focus of interest was to evaluate the significance of immunohistochemical analysis in diagnosis of such extremely rare neoplasms. In the PubMed and Google Search, we found only 39 cases of nasal angifibroma, 27 males and 12 females from 1980 to 2012. The most prevalent site of origin was nasal septum, followed by inferior and middle turbinate. The commonest symptoms were nasal obstruction and epistaxis. Nasal angiofibromas are clinically distinct from nasopharyneal angiofibromas and can therefore be misdiagnosed. The differential diagnosis includes other vascular lesions, such as lobular capillary hemangioma and sinonasal-type hemangiopericytoma. Although immunohistochemistry is not necessary for differentiation between angiofibroma and capillary hemangioma, that diagnostic procedure may be helpful in distinction from sinonasal hemangiopericytoma. As an ilustration for immunohistochemical analysis, we presented a case of an elderly woman with tumor arising from the middle turbinate, diagnosed as angiofibroma. The staining was positive for CD34, CD31, factor VIII, vimentin and smooth muscle alpha-actin, and negative for desmin.

• MeSH
• angiofibrom komplikace   diagnóza   metabolismus   MeSH
• biopsie MeSH
• diferenciální diagnóza MeSH
• imunohistochemie metody   MeSH
• lidé středního věku MeSH
• lidé MeSH
• nádorové biomarkery metabolismus   MeSH
• nádory nosu komplikace   diagnóza   metabolismus   MeSH
• nosní dutina patologie   MeSH
• nosní obstrukce diagnóza   etiologie   metabolismus   MeSH
• počítačová rentgenová tomografie MeSH
• Check Tag
• lidé středního věku MeSH
• lidé MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• kazuistiky MeSH
• přehledy MeSH
• Názvy látek
• nádorové biomarkery MeSH

The localization of dipeptidylpeptidase IV (DPP IV) activity was studied at light microscope level in the mucosa, glands and capillary endothelium of the human foetuses and rat, mouse and guinea pig in some prenatal and postnatal terms. Alkaline phosphatase reaction was used for complete histochemical demonstration of capillary endothelium. The two enzymes were mapped by Lojda's methods (12). The study brings knowledge of the localization of DPP IV activity in the nasal cavity structures and gives a different time survey of the onset of DPP IV activity during ontogenesis. Considering this activity we can presume that this membrane-bound protease DPP IV may participate in the metabolism of neuropeptides in the nasal cavity and play some role in immunological disturbances of patients with rhinitis.

• MeSH
• cévní endotel enzymologie   MeSH
• dipeptidylpeptidasa 4 MeSH
• dipeptidylpeptidasy a tripeptidylpeptidasy analýza   MeSH
• histocytochemie MeSH
• krysa rodu Rattus MeSH
• lidé MeSH
• morčata MeSH
• myši MeSH
• nosní dutina krevní zásobení   enzymologie   MeSH
• plod enzymologie   MeSH
• zvířata MeSH
• Check Tag
• krysa rodu Rattus MeSH
• lidé MeSH
• morčata MeSH
• myši MeSH
• zvířata MeSH
• Publikační typ
• časopisecké články MeSH
• Názvy látek
• dipeptidylpeptidasa 4 MeSH
• dipeptidylpeptidasy a tripeptidylpeptidasy MeSH