Penicillin Dotaz Zobrazit nápovědu
- Klíčová slova
- PENICILLIN/therapeutic use *,
- MeSH
- peniciliny terapeutické užití MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- peniciliny MeSH
Penicillin G (2%, w/v in phosphate buffer, pH 8) was hydrolysed in a flow-through, miniature electro-membrane reactor with the penicillin G acylase immobilized in 5% (w/v) polyacrylamide (diam. 10 mm, thickness 2.6 mm, enzyme activity 24 U ml(-1)). The conversion of penicillin G increased from 0.15 to almost 0.5 when the electric current applied to the reactor was changed from -600 to +600 A/m2 with a substrate residency of 1 h.
- MeSH
- aktivace enzymů MeSH
- bioreaktory * MeSH
- design vybavení MeSH
- elektrochemie přístrojové vybavení metody MeSH
- elektromagnetická pole MeSH
- enzymy imobilizované chemie MeSH
- hydrolýza MeSH
- kyselina penicilanová analogy a deriváty chemická syntéza MeSH
- membrány umělé * MeSH
- penicilin G chemie MeSH
- penicilinamidasa chemie MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Názvy látek
- aminopenicillanic acid MeSH Prohlížeč
- enzymy imobilizované MeSH
- kyselina penicilanová MeSH
- membrány umělé * MeSH
- penicilin G MeSH
- penicilinamidasa MeSH
The lymphocyte blastic transformation (TTB), leucocyte and macrophage inhibition tests has been compared in 18 hypersensitive to penicillin patients and in 15 patients with hypersensitivity to PPD. It has been shown that TTB was positive in all penicillin allergy cases, due to the constantly LT sensitization, and therefore this test constitutes an efficient method for the in vitro diagnosis of penicillin hypersensitivity. Macrophage inhibitory factor (MIF) was absent in all penicillin allergic subjects. Leucocyte migration inhibition test was positive only when gamma globulin coupled penicillin was used or in the presence of autologous plasma pretreated penicillin. This suggests that leucocyte migration inhibition resulted from the specific penicillin antibodies.
- MeSH
- aktivace lymfocytů MeSH
- inhibice migrace buněk * MeSH
- léková alergie imunologie MeSH
- leukocyty imunologie MeSH
- lidé MeSH
- makrofágy imunologie MeSH
- penicilin G škodlivé účinky imunologie MeSH
- peniciliny škodlivé účinky imunologie MeSH
- pozdní přecitlivělost chemicky indukované imunologie MeSH
- tuberkulin škodlivé účinky imunologie MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- srovnávací studie MeSH
- Názvy látek
- penicilin G MeSH
- peniciliny MeSH
- tuberkulin MeSH
- MeSH
- Neisseria gonorrhoeae účinky léků MeSH
- peniciliny farmakologie MeSH
- rezistence na penicilin MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- peniciliny MeSH
- Klíčová slova
- PENICILLIN *, SYPHILIS *,
- MeSH
- peniciliny * MeSH
- syfilis * MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- peniciliny * MeSH
The development of the motor reaction to i.v. injection of the sodium salt of penicillin G in a dose of 0.9 x 10(6) I.U./kg egg weight was studied in chick embryos (normal and spinal) from the 11th to the 19th day of incubation. Penicillin first caused standard activation of embryonal motility from the 15th day of incubation, in both normal and spinal embryos. Activation was at first continuous in character (a twofold increase in the frequency of spontaneous movements). In 17- and particularly in 19-day embryos a typical paroxysmal reaction developed, with pronounced intervals of motor rest. The proportion of the spinal component in the penicillin reaction was abut 40% and of the supraspinal component about 60% of total motor activity. In older embryos (after the 15th day of incubation), the motor reaction to penicillin could be effectively modified by the systemic administration of glycine and GABA. It is concluded from the results that penicillin does not activate embryonal motor activity until a given stage of development of the CNS has been attained. It is a developmental phenomenon with a spinal and a supraspinal component, in which central inhibitory mechanisms participate.
- MeSH
- GABA farmakologie MeSH
- glycin farmakologie MeSH
- kuřecí embryo fyziologie MeSH
- mícha fyziologie MeSH
- penicilin G farmakologie MeSH
- pohyb účinky léků MeSH
- zvířata MeSH
- Check Tag
- kuřecí embryo fyziologie MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- GABA MeSH
- glycin MeSH
- penicilin G MeSH
- Klíčová slova
- PENICILLIN *,
- MeSH
- lidé MeSH
- peniciliny * MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- peniciliny * MeSH
In vitro susceptibility of eight antibiotics was compared using three groups of pneumococci and agar dilution method comprising 30 penicillin-susceptible, 30 intermediately penicillin-resistant, and 30 highly penicillin-resistant pneumococci. Decreased sensitivity to all beta-lactam agents of intermediately penicillin-resistant and highly penicillin-resistant pneumococci is shown. MIC50 and MIC90 was lower with amoxicillin with and without clavulanate by one dilution than with penicillin. Cephalosporin MIC90s were all significantly higher for intermediately resistant and fully resistant strains. Only imipenem was more active than penicillin with MIC90 of susceptible pneumococci 0.015 mg/L, intermediately resistant pneumococci 0.25 mg/L, resistant pneumococci 1 mg/L.
- MeSH
- antibakteriální látky farmakologie MeSH
- cefalosporiny farmakologie MeSH
- laktamy farmakologie MeSH
- lidé MeSH
- mikrobiální testy citlivosti MeSH
- penicilin G farmakologie MeSH
- peniciliny farmakologie MeSH
- pneumokokové infekce mikrobiologie MeSH
- rezistence na penicilin * MeSH
- Streptococcus pneumoniae účinky léků MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- srovnávací studie MeSH
- Názvy látek
- antibakteriální látky MeSH
- cefalosporiny MeSH
- laktamy MeSH
- penicilin G MeSH
- peniciliny MeSH
- Klíčová slova
- ERYSIPELAS *, PENICILLIN G, BENZATHINE *,
- MeSH
- benzathin-penicilin G * MeSH
- erysipel * MeSH
- ethylendiaminy * MeSH
- injekce * MeSH
- lidé MeSH
- penicilin G * MeSH
- peniciliny * MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- benzathin-penicilin G * MeSH
- benzathine MeSH Prohlížeč
- ethylendiaminy * MeSH
- penicilin G * MeSH
- peniciliny * MeSH
- Klíčová slova
- PENICILLIN/therapy *, TUBERCULOSIS/therapy *,
- MeSH
- peniciliny terapie MeSH
- tuberkulóza terapie MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- peniciliny MeSH