The susceptibility of Bacillus subtilis to amino acid analogues was found to be markedly influenced by the carbon source used in the test media. Thialysine inhibited the bacterium with a greater number of carbon sources than the other two analogues tested. 5-Hydroxylysine was inhibitory with glycerol, lactose, D-xylose, L-arabinose and soluble starch while ethionine showed toxicity with lactose, D-xylose and L-arabinose. None of these analogues were toxic at the levels tested when D-galactose was used as carbon source. The bacterium was not susceptible to thialysine with glycerol, to 5-hydroxylysine with L-arabinose and to ethionine with lactose.

• MeSH
• Arabinose metabolism   MeSH
• Bacillus subtilis drug effects   metabolism   MeSH
• Cysteine analogs & derivatives   pharmacology   MeSH
• Ethionine pharmacology   MeSH
• Glucose metabolism   MeSH
• Glycerol metabolism   MeSH
• Hydroxylysine pharmacology   MeSH
• Maltose metabolism   MeSH
• Mannitol metabolism   MeSH
• Carbohydrate Metabolism * MeSH
• Publication type
• Journal Article MeSH
• Comparative Study MeSH
• Names of Substances
• Arabinose MeSH
• Cysteine MeSH
• Ethionine MeSH
• Glucose MeSH
• Glycerol MeSH
• Hydroxylysine MeSH
• Maltose MeSH
• Mannitol MeSH
• S-2-aminoethyl cysteine MeSH Browser