• Je něco špatně v tomto záznamu ?

Kostní denzita u diabetiků 1. typu obou pohlaví s ohledem na složení kosti
[Bone mineral density of both genders in Type 1 diabetes according to bone composition]

Dimitrios J. Hadjidakis, A. E. Raptis, M. Sfakianakis, A. Mylonakis, S. A. Raptis

. 2007 ; 5 (2) : 110-116.

Jazyk čeština Země Česko

Perzistentní odkaz   https://www.medvik.cz/link/bmc07502076

AIMS: This study is an investigation of the impact of Type 1 diabetes on bone mineral density (BMD) with regard to bone composition. MATERIAL AND METHODS: Thirty male and 30 premenopausal female patients with Type 1 diabetes (IDD) were retrospectively compared with an equal number of healthy individuals, matched on a person-to-person basis and to the reference population mean. BMD was measured at the L2-L4 vertebrae and femoral neck (FN) by dual energy X-ray absorptiometry (DXA). RESULTS: BMD absolute values were significantly lower in the diabetic than in the healthy males at vertebrae and FN (P<.05). The vertebral BMD values of diabetic women did not significantly differ, whereas those of FN were significantly lower compared with those of the healthy participants. FN age-adjusted BMD values (Z scores) were significantly lower than those of the healthy persons and the population reference mean in both genders (P=.01, <.001 for males and <.01 for females), whereas regarding the vertebrae, only in the diabetic males (P<.05 and <.01 respectively). The percentages of osteopenia and osteoporosis were significantly higher in the male compared to the female diabetic patients (P<.001). No significant correlations existed between the BMD values and diabetes duration, glycosylated hemoglobin (HbA1c) concentration, or age of diabetes onset. Similar results were obtained when applying stepwise multiple regression analysis to explain the BMD value variance. CONCLUSIONS: Young males with Type 1 diabetes exhibit significantly lower BMD values of trabecular and mixed cortical-trabecular bone, compared with matched healthy persons. Premenopausal females with Type 1 diabetes present significantly lower BMD values of mixed bone only. Blood glucose control and diabetes duration do not appear to influence BMD behavior.

Bone mineral density of both genders in Type 1 diabetes according to bone composition

Recenze v:

Komentář [k článku Kostní denzita u diabetiků 1. typu obou pohlaví s ohledem na složení kosti].

Bibliografie atd.

Lit.: 27

000      
03905naa 2200457 a 4500
001      
bmc07502076
003      
CZ-PrNML
005      
20111210121327.0
008      
080213s2007 xr e cze||
009      
AR
040    __
$a ABA008 $b cze $c ABA008 $d ABA008 $e AACR2
041    0_
$a cze $b eng
044    __
$a xr
100    1_
$a Hadjidakis, Dimitrios J.
245    10
$a Kostní denzita u diabetiků 1. typu obou pohlaví s ohledem na složení kosti / $c Dimitrios J. Hadjidakis, A. E. Raptis, M. Sfakianakis, A. Mylonakis, S. A. Raptis
246    11
$a Bone mineral density of both genders in Type 1 diabetes according to bone composition
314    __
$a 2nd Department of Internal Medicine-Propaedeutic, Research Institute and Diabetes Center, Attikon and Evgenidion Hospitals, Athens University, Athens
504    __
$a Lit.: 27
520    9_
$a AIMS: This study is an investigation of the impact of Type 1 diabetes on bone mineral density (BMD) with regard to bone composition. MATERIAL AND METHODS: Thirty male and 30 premenopausal female patients with Type 1 diabetes (IDD) were retrospectively compared with an equal number of healthy individuals, matched on a person-to-person basis and to the reference population mean. BMD was measured at the L2-L4 vertebrae and femoral neck (FN) by dual energy X-ray absorptiometry (DXA). RESULTS: BMD absolute values were significantly lower in the diabetic than in the healthy males at vertebrae and FN (P<.05). The vertebral BMD values of diabetic women did not significantly differ, whereas those of FN were significantly lower compared with those of the healthy participants. FN age-adjusted BMD values (Z scores) were significantly lower than those of the healthy persons and the population reference mean in both genders (P=.01, <.001 for males and <.01 for females), whereas regarding the vertebrae, only in the diabetic males (P<.05 and <.01 respectively). The percentages of osteopenia and osteoporosis were significantly higher in the male compared to the female diabetic patients (P<.001). No significant correlations existed between the BMD values and diabetes duration, glycosylated hemoglobin (HbA1c) concentration, or age of diabetes onset. Similar results were obtained when applying stepwise multiple regression analysis to explain the BMD value variance. CONCLUSIONS: Young males with Type 1 diabetes exhibit significantly lower BMD values of trabecular and mixed cortical-trabecular bone, compared with matched healthy persons. Premenopausal females with Type 1 diabetes present significantly lower BMD values of mixed bone only. Blood glucose control and diabetes duration do not appear to influence BMD behavior.
650    _2
$a diabetes mellitus 1. typu $x komplikace $7 D003922
650    _2
$a nemoci kostí $x etiologie $x komplikace $x metabolismus $7 D001847
650    _2
$a kostní denzita $x fyziologie $7 D015519
650    _2
$a metabolické nemoci kostí $x etiologie $x komplikace $7 D001851
650    _2
$a osteoporóza $x etiologie $x komplikace $x metabolismus $7 D010024
650    _2
$a retrospektivní studie $7 D012189
650    _2
$a financování organizované $7 D005381
650    _2
$a regresní analýza $7 D012044
650    _2
$a lidé $7 D006801
700    1_
$a Raptis, A. E.
700    1_
$a Sfakianakis, M.
700    1_
$a Mylonakis, A.
700    1_
$a Raptis, S. A.
773    0_
$w MED00013409 $t Journal of diabetes and its complications $g Roč. 5, č. 2 (2007), s. 110-116 $x 1214-0937
787    18
$w bmc07502077 $i Recenze v: $t Komentář
910    __
$a ABA008 $b B 2302 $c 134 $y 1
990    __
$a 20080213103212 $b ABA008
991    __
$a 20090430131451 $b ABA008
999    __
$a ok $b bmc $g 617689 $s 470121
BAS    __
$a 3
BMC    __
$a 2007 $b 5 $c 2 $d 110-116 $i 1214-0937 $m Journal of Diabetes and its Complications (České vyd.) $x MED00013409
LZP    __
$a 2007-20/mkal

Najít záznam

Citační ukazatele

Pouze přihlášení uživatelé

Možnosti archivace