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Electrolyte disorders
D. Bockenhauer, J. Zieg,
Jazyk angličtina Země Spojené státy americké
Typ dokumentu časopisecké články, přehledy
- MeSH
- hodnoty glomerulární filtrace MeSH
- ledviny metabolismus patofyziologie MeSH
- lidé MeSH
- nemoci ledvin etiologie metabolismus patofyziologie MeSH
- novorozenec MeSH
- vodní a elektrolytová nerovnováha komplikace metabolismus MeSH
- Check Tag
- lidé MeSH
- novorozenec MeSH
- Publikační typ
- časopisecké články MeSH
- přehledy MeSH
Electrolyte disorders can result in life-threatening complications. The kidneys are tasked with maintaining electrolyte homoeostasis, yet the low glomerular filtration rate of neonatal kidneys, tubular immaturity, and high extrarenal fluid losses contribute to increased occurrence of electrolyte disorders in neonates. Understanding the physiologic basis of renal electrolyte handling is crucial in identifying underlying causes and initiation of proper treatment. This article reviews key aspects of renal physiology, the diagnostic workup of disorders of plasma sodium and potassium, and the appropriate treatment, in addition to inherited disorders associated with neonatal electrolyte disturbances that illuminate the physiology of renal electrolyte handling.
Citace poskytuje Crossref.org
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- $a Bockenhauer, Detlef $u UCL Institute of Child Health, Great Ormond Street Hospital for Children NHS Foundation Trust, Nephrology Unit, 30 Guilford Street, London WC1 3EH, UK. Electronic address: d.bockenhauer@ucl.ac.uk.
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- $a Electrolyte disorders can result in life-threatening complications. The kidneys are tasked with maintaining electrolyte homoeostasis, yet the low glomerular filtration rate of neonatal kidneys, tubular immaturity, and high extrarenal fluid losses contribute to increased occurrence of electrolyte disorders in neonates. Understanding the physiologic basis of renal electrolyte handling is crucial in identifying underlying causes and initiation of proper treatment. This article reviews key aspects of renal physiology, the diagnostic workup of disorders of plasma sodium and potassium, and the appropriate treatment, in addition to inherited disorders associated with neonatal electrolyte disturbances that illuminate the physiology of renal electrolyte handling.
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- $a Zieg, Jakub $u Department of Pediatrics, 2nd Faculty of Medicine, Charles University in Prague and Motol University Hospital, V Úvalu 84, 15006 Praha 5, Czech Republic.
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