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Pleistocene Mitochondrial Genomes Suggest a Single Major Dispersal of Non-Africans and a Late Glacial Population Turnover in Europe
C. Posth, G. Renaud, A. Mittnik, DG. Drucker, H. Rougier, C. Cupillard, F. Valentin, C. Thevenet, A. Furtwängler, C. Wißing, M. Francken, M. Malina, M. Bolus, M. Lari, E. Gigli, G. Capecchi, I. Crevecoeur, C. Beauval, D. Flas, M. Germonpré, J....
Jazyk angličtina Země Anglie, Velká Británie
Typ dokumentu časopisecké články, práce podpořená grantem
NLK
Cell Press Free Archives
od 1995-01-01 do Před 1 rokem
Free Medical Journals
od 1995 do Před 1 rokem
- MeSH
- běloši genetika MeSH
- černoši genetika MeSH
- emigrace a imigrace MeSH
- genetická variace MeSH
- genom lidský * MeSH
- genom mitochondriální MeSH
- haplotypy MeSH
- lidé MeSH
- mitochondriální DNA genetika MeSH
- starobylá DNA * MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Geografické názvy
- Afrika MeSH
- Evropa MeSH
How modern humans dispersed into Eurasia and Australasia, including the number of separate expansions and their timings, is highly debated [1, 2]. Two categories of models are proposed for the dispersal of non-Africans: (1) single dispersal, i.e., a single major diffusion of modern humans across Eurasia and Australasia [3-5]; and (2) multiple dispersal, i.e., additional earlier population expansions that may have contributed to the genetic diversity of some present-day humans outside of Africa [6-9]. Many variants of these models focus largely on Asia and Australasia, neglecting human dispersal into Europe, thus explaining only a subset of the entire colonization process outside of Africa [3-5, 8, 9]. The genetic diversity of the first modern humans who spread into Europe during the Late Pleistocene and the impact of subsequent climatic events on their demography are largely unknown. Here we analyze 55 complete human mitochondrial genomes (mtDNAs) of hunter-gatherers spanning ∼35,000 years of European prehistory. We unexpectedly find mtDNA lineage M in individuals prior to the Last Glacial Maximum (LGM). This lineage is absent in contemporary Europeans, although it is found at high frequency in modern Asians, Australasians, and Native Americans. Dating the most recent common ancestor of each of the modern non-African mtDNA clades reveals their single, late, and rapid dispersal less than 55,000 years ago. Demographic modeling not only indicates an LGM genetic bottleneck, but also provides surprising evidence of a major population turnover in Europe around 14,500 years ago during the Late Glacial, a period of climatic instability at the end of the Pleistocene.
Archéosphère 2 Rue des Noyers 11500 Quirbajou France
Centre for Isotope Research Groningen University Nijenborgh 4 9747 AG Groningen the Netherlands
CNRS UMR 7041 ArScAn MAE 21 Allée de l'Université 92023 Nanterre France
Dipartimento di Biologia Università di Firenze Via del Proconsolo 12 50122 Florence Italy
Faculty of Archaeology Leiden University PO Box 9514 2300 RA Leiden the Netherlands
INRAP UMR 8215 Trajectoires 21 Allée de l'Université 92023 Nanterre France
Max Planck Institute for Evolutionary Anthropology Deutscher Platz 6 04103 Leipzig Germany
Max Planck Institute for the Science of Human History Kahlaische Straße 10 07745 Jena Germany
Royal Belgian Institute of Natural Sciences 29 Vautier Street 1000 Brussels Belgium
Service Régional d'Archéologie de Franche Comté 7 Rue Charles Nodier 25043 Besançon Cedex France
Citace poskytuje Crossref.org
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- $a Posth, Cosimo $u Institute for Archaeological Sciences, Archaeo- and Palaeogenetics, University of Tübingen, Rümelinstraße 23, 72070 Tübingen, Germany. Electronic address: posth@shh.mpg.de.
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