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Intra-epithelial lymphocytosis of the ileum: A pathological clue to clinically occult adult celiac disease
Hugh J. Freeman, Doug Webber
Jazyk angličtina Země Spojené státy americké
Typ dokumentu kazuistiky
- MeSH
- biopsie MeSH
- celiakie * diagnóza dietoterapie MeSH
- dospělí MeSH
- enteritida MeSH
- ileitida MeSH
- ileum cytologie patologie MeSH
- intraepiteliální lymfocyty patologie MeSH
- kolitida lymfocytární MeSH
- kolon cytologie patologie MeSH
- lidé MeSH
- lymfocytóza MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- mužské pohlaví MeSH
- Publikační typ
- kazuistiky MeSH
A 39-yr-old male presented with diarrhea, weight loss and rectal bleeding. Hemorrhoids were present but the colon and distal ileum were macroscopically normal. Random mucosal biopsies of the ileum and multiple sites in the colon revealed extensive ileal and focal cecal intra-epithelial lymphocytosis. Subsequent duodenal mucosal biopsies confirmed the suspicion of adult celiac disease. Later endoscopic biopies done after gluten-free diet treatment were normal. This report demonstrates that intra-epithelial lymphocytosis in the ileum may be an important pathological clue to underlying clinically occult adult celiac disease.
Department of Pathology University of British Columbia Vancouver BC Canada
Departments of Medicine University of British Columbia Vancouver BC Canada
Citace poskytuje Crossref.org
Literatura
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- $a A 39-yr-old male presented with diarrhea, weight loss and rectal bleeding. Hemorrhoids were present but the colon and distal ileum were macroscopically normal. Random mucosal biopsies of the ileum and multiple sites in the colon revealed extensive ileal and focal cecal intra-epithelial lymphocytosis. Subsequent duodenal mucosal biopsies confirmed the suspicion of adult celiac disease. Later endoscopic biopies done after gluten-free diet treatment were normal. This report demonstrates that intra-epithelial lymphocytosis in the ileum may be an important pathological clue to underlying clinically occult adult celiac disease.
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