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Early pancreatic carcinogenesis - risk factors, early symptoms, and the impact of antidiabetic drugs

P. Frič, J. Škrha, A. Šedo, P. Bušek, K. Kmochová, M. Laclav, S. Solař, B. Bunganič, M. Zavoral,

. 2016 ; 28 (7) : e19-25.

Jazyk angličtina Země Anglie, Velká Británie

Typ dokumentu časopisecké články, přehledy

Perzistentní odkaz   https://www.medvik.cz/link/bmc17031771

Grantová podpora
NT14254 MZ0 CEP - Centrální evidence projektů

Risk factors (long-term diabetes, obesity) and early symptoms (new-onset diabetes, loss of weight, or persistent low body mass) are the initial symptoms of pancreatic carcinogenesis. They may be influenced by antidiabetic drugs and their correct evaluation is a prerequisite for early diagnosis of pancreatic cancer (PC). We review the risk factors, early symptoms, and the impact of antidiabetic drugs on early pancreatic carcinogenesis. The main source of data was the database Medline/PubMed and abstracts of international congresses (DDW, UEGW). The risk factors and early symptoms are integral components of the familial PC surveillance and sporadic PC screening. Preventive programs should always be include multistep and multidisciplinary procedures. The correct evaluation of antidiabetic drugs and their interactions with other components of pancreatic carcinogenesis may influence the early diagnosis of PC.

Citace poskytuje Crossref.org

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