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Epidemiology, diagnosis, preoperative evaluation and prognostic assessment of upper-tract urothelial carcinoma (UTUC)
F. Soria, SF. Shariat, SP. Lerner, HM. Fritsche, M. Rink, W. Kassouf, PE. Spiess, Y. Lotan, D. Ye, MI. Fernández, E. Kikuchi, DC. Chade, M. Babjuk, AP. Grollman, GN. Thalmann,
Jazyk angličtina Země Německo
Typ dokumentu časopisecké články, přehledy
NLK
ProQuest Central
od 1997-02-01 do Před 1 rokem
Medline Complete (EBSCOhost)
od 2000-02-01 do Před 1 rokem
Health & Medicine (ProQuest)
od 1997-02-01 do Před 1 rokem
- MeSH
- dědičné nepolypózní kolorektální nádory epidemiologie MeSH
- karcinom z přechodných buněk diagnostické zobrazování epidemiologie patologie chirurgie MeSH
- kyseliny aristolochové metabolismus MeSH
- ledvinná pánvička diagnostické zobrazování patologie chirurgie MeSH
- lidé MeSH
- lymfadenektomie MeSH
- nádory ledvin diagnostické zobrazování epidemiologie patologie chirurgie MeSH
- nádory močového měchýře epidemiologie MeSH
- nádory močovodu diagnostické zobrazování epidemiologie patologie chirurgie MeSH
- neoadjuvantní terapie MeSH
- předoperační péče MeSH
- prognóza MeSH
- rizikové faktory MeSH
- ureteroskopie MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- přehledy MeSH
PURPOSE: Upper-tract urothelial carcinoma (UTUC) is a relatively uncommon disease with limited available evidence on specific topics. The purpose of this article was to review the previous literature to summarize the current knowledge about UTUC epidemiology, diagnosis, preoperative evaluation and prognostic assessment. METHODS: Using MEDLINE, a non-systematic review was performed including articles between January 2000 and February 2016. English language original articles, reviews and editorials were selected based on their clinical relevance. RESULTS: UTUC accounts for 5-10 % of all urothelial cancers, with an increasing incidence. UTUC and bladder cancer share some common risk factors, even if they are two different entities regarding practical, biological and clinical characteristics. Aristolochic acid plays an important role in UTUC pathogenesis in certain regions. It is further estimated that approximately 10 % of UTUC are part of the hereditary non-polyposis colorectal cancer spectrum disease. UTUC diagnosis remains mainly based on imaging and endoscopy, but development of new technologies is rapidly changing the diagnosis algorithm. To help the decision-making process regarding surgical treatment, extent of lymphadenectomy and selection of neoadjuvant systemic therapies, predictive tools based on preoperative patient and tumor characteristics have been developed. CONCLUSIONS: Awareness regarding epidemiology, diagnosis, preoperative evaluation and prognostic assessment changes is essential to correctly diagnose and manage UTUC patients, thereby potentially improving their outcomes.
Department of Genitourinary Oncology Moffitt Cancer Center Tampa FL USA
Department of Surgery McGill University Montreal QC Canada
Department of Urology Bern University Hospital Bern Switzerland
Department of Urology Caritas St Josef Medical Centre University of Regensburg Regensburg Germany
Department of Urology Clinica Alemana Santiago Chile
Department of Urology Fudan University Shanghai Cancer Center Shanghai China
Department of Urology Keio University School of Medicine Tokyo Japan
Department of Urology University Medical Center Hamburg Eppendorf Hamburg Germany
Department of Urology University of Texas Southwestern Medical Center Dallas TX USA
Scott Department of Urology Baylor College of Medicine Houston TX USA
Urology Department University of Sao Paulo Medical School and Institute of Cancer São Paulo Brazil
Citace poskytuje Crossref.org
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- $a PURPOSE: Upper-tract urothelial carcinoma (UTUC) is a relatively uncommon disease with limited available evidence on specific topics. The purpose of this article was to review the previous literature to summarize the current knowledge about UTUC epidemiology, diagnosis, preoperative evaluation and prognostic assessment. METHODS: Using MEDLINE, a non-systematic review was performed including articles between January 2000 and February 2016. English language original articles, reviews and editorials were selected based on their clinical relevance. RESULTS: UTUC accounts for 5-10 % of all urothelial cancers, with an increasing incidence. UTUC and bladder cancer share some common risk factors, even if they are two different entities regarding practical, biological and clinical characteristics. Aristolochic acid plays an important role in UTUC pathogenesis in certain regions. It is further estimated that approximately 10 % of UTUC are part of the hereditary non-polyposis colorectal cancer spectrum disease. UTUC diagnosis remains mainly based on imaging and endoscopy, but development of new technologies is rapidly changing the diagnosis algorithm. To help the decision-making process regarding surgical treatment, extent of lymphadenectomy and selection of neoadjuvant systemic therapies, predictive tools based on preoperative patient and tumor characteristics have been developed. CONCLUSIONS: Awareness regarding epidemiology, diagnosis, preoperative evaluation and prognostic assessment changes is essential to correctly diagnose and manage UTUC patients, thereby potentially improving their outcomes.
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