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Iterative Photoinduced Chain Functionalization as a Generic Platform for Advanced Polymeric Drug Delivery Systems
AA. Samad, A. Bethry, O. Janouskova, J. Ciccione, C. Wenk, JL. Coll, G. Subra, T. Etrych, FE. Omar, Y. Bakkour, J. Coudane, B. Nottelet,
Macromolecular rapid communications.
2018 ;
39 (3) :
.
[pub] 20171102
Language English Country Germany
Document type Journal Article
Persistent link
https://www.medvik.cz/link/bmc18033607
- MeSH
- Alkynes chemistry MeSH
- Photochemical Processes * MeSH
- HEK293 Cells MeSH
- Curcumin administration & dosage chemistry MeSH
- Drug Delivery Systems methods MeSH
- Humans MeSH
- Cell Line, Tumor MeSH
- Nanostructures administration & dosage chemistry MeSH
- Polyesters chemistry MeSH
- Polyethylene Glycols chemistry MeSH
- Antineoplastic Agents administration & dosage chemistry MeSH
- Sulfhydryl Compounds chemistry MeSH
- Cell Survival drug effects MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
Advanced drug delivery systems (DDS) are easily designed following a photoiterative strategy. Multifunctional polymers are obtained by coupling building blocks of interest to an alkynated poly(ε-caprolactone) (PCL) platform via an efficient thiol-yne photoaddition. Fine-tuning over the design is achieved, as illustrated with targeting and enzyme-responsive DDS.
IBMM Univ Montpellier CNRS ENSCM Montpellier France
INSERM U1209 Institut Albert Bonniot Université Grenoble Alpes F 38000 Grenoble France
Laboratory of applied Chemistry Faculty of Science 3 Lebanese University P O Box 826 Tripoli Lebanon
References provided by Crossref.org
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