The metabolic syndrome: relationship between insulin sensitivity and the role of peroxisome proliferator-activated receptors (PPARs) in saccharide and lipid metabolism
Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia.
2005 Dec ;
149 (2) :
237-41.
Language English Country Czech Republic Media print
Document type Journal Article, Review
Persistent link
https://www.medvik.cz/link/pmid16601762
PubMed
16601762
Knihovny.cz E-resources
- MeSH
- Diabetes Mellitus, Type 1 metabolism MeSH
- Glucose metabolism MeSH
- Insulin Resistance * MeSH
- Humans MeSH
- Metabolic Syndrome metabolism MeSH
- Lipid Metabolism * MeSH
- Peroxisome Proliferator-Activated Receptors physiology MeSH
- Adipose Tissue metabolism MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
- Review MeSH
- Names of Substances
- Glucose MeSH
- Peroxisome Proliferator-Activated Receptors MeSH
Peroxisome proliferator-activated receptors (PPARs) are subgroups of nuclear hormonal receptors of transcripting factors mostly found in adipose tissue. They are described as important regulators of lipid and saccharide metabolism including insulin sensitivity; therefore they are taken as marker of metabolic syndrome. Their synthetic ligands could be used as drugs for insulin resistance and type 2 diabetes mellitus.
