Adjuvant effect of Bacillus firmus in intranasal immunization of guinea pigs with inactivated type B infuenza virus
Language English Country United States Media print
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
16821727
DOI
10.1007/bf02932172
Knihovny.cz E-resources
- MeSH
- Adjuvants, Immunologic * MeSH
- Bacillus immunology MeSH
- Guinea Pigs MeSH
- Antibodies, Viral analysis MeSH
- Serologic Tests methods MeSH
- Vaccination methods MeSH
- Influenza Vaccines immunology MeSH
- Influenza B virus immunology MeSH
- Animals MeSH
- Check Tag
- Guinea Pigs MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- Adjuvants, Immunologic * MeSH
- Antibodies, Viral MeSH
- Influenza Vaccines MeSH
Intranasal immunization of guinea pigs with inactivated type B influenza virus plus inactivated Bacillus firmus as an adjuvant compared to the virus alone yields higher titers of serum hemagglutination-inhibiting antibodies and virus-neutralizing antibodies. This phenomenon could be useful in standard serology, especially in the preparation of immune sera against highly pathogenic strains for in vitro diagnosis.
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