Detection of Treponema pallidum subsp. pallidum from skin lesions, serum, and cerebrospinal fluid in an infant with congenital syphilis after clindamycin treatment of the mother during pregnancy
Language English Country United States Media print-electronic
Document type Case Reports, Journal Article, Research Support, Non-U.S. Gov't
PubMed
17151205
PubMed Central
PMC1829021
DOI
10.1128/jcm.02209-06
PII: JCM.02209-06
Knihovny.cz E-resources
- MeSH
- Anti-Bacterial Agents therapeutic use MeSH
- DNA, Bacterial * blood cerebrospinal fluid MeSH
- Adult MeSH
- Pregnancy Complications, Infectious drug therapy microbiology MeSH
- Clindamycin therapeutic use MeSH
- Skin microbiology MeSH
- Humans MeSH
- Infant, Premature, Diseases microbiology MeSH
- Infant, Premature MeSH
- Infant, Low Birth Weight MeSH
- Infant, Newborn MeSH
- Syphilis drug therapy microbiology MeSH
- Pregnancy MeSH
- Treponema pallidum genetics isolation & purification MeSH
- Syphilis, Congenital microbiology MeSH
- Check Tag
- Adult MeSH
- Humans MeSH
- Male MeSH
- Infant, Newborn MeSH
- Pregnancy MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Case Reports MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- Anti-Bacterial Agents MeSH
- DNA, Bacterial * MeSH
- Clindamycin MeSH
We report here a case of congenital syphilis in a newborn after clindamycin treatment in pregnancy. Using PCR detection of tmpC (TP0319) and DNA sequencing of the genes TP0136 and TP0548, DNA sequences identical to Treponema pallidum subsp. pallidum strain SS14 were detected in the infant's skin lesions, serum, and cerebrospinal fluid.
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