The current incidence of Escherichia coli strains in healthy humans capable of producing the inhibitory exoproducts, such as temperate bacteriophages, corpuscular or HMW (high-molar mass) and proteinaceous or LMW (low-molar mass) colicins and siderophores was determined. Fifty-three E. coli strains were collected from the colons of 53 healthy human volunteers in Brno (Czechia) and tested for spontaneous and induced production of inhibitory exoproducts in a cross-test against each other. Of the strains tested, 37.7% produced bacteriophages, 41.5% produced from one to several LMW colicins, 11.3% formed HMW colicins and 15.1% (eight strains) produced exocellular siderophores different from enterochelin. Of these, seven strains formed aerobactin and one strain formed an untyped siderophore. E. coli strains differ greatly in the incidence of colicinogeny and lysogeny from its closest systemic relatives in the genus Escherichia and therefore should not be regarded as a model bacterium in this respect.

Department of Biology Faculty of Medicine Masaryk University 602 00 Brno Czechia

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Ann Inst Pasteur Microbiol. 1986 Nov-Dec;137B(3):297-303 PubMed

Cesk Gastroenterol Vyz. 1983 Mar;37(2):81-6 PubMed

J Gen Microbiol. 1965 Nov;41(2):151-4 PubMed

Mol Gen Genet. 1983;192(1-2):131-9 PubMed

J Med Microbiol. 2003 Aug;52(Pt 8):637-42 PubMed

J Hyg Epidemiol Microbiol Immunol. 1960;4:151-65 PubMed

J Basic Microbiol. 2001;41(6):367-74 PubMed

FEMS Microbiol Lett. 2002 Mar 5;208(2):259-62 PubMed

Folia Microbiol (Praha). 2003;48(2):281-7 PubMed

J Basic Microbiol. 2002;42(6):429-33 PubMed

Microbiol Immunol. 1995;39(6):401-4 PubMed

Folia Microbiol (Praha). 2004;49(6):671-8 PubMed

Acta Microbiol Pol (1952). 1964;13:273-81 PubMed

Epidemiol Infect. 2000 Aug;125(1):71-8 PubMed

FEMS Immunol Med Microbiol. 1997 Apr;17(4):263-71 PubMed

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