Stimulation of protective and cross-protective immunity against influenza B virus after adjuvant mucosal immunization of mice
Language English Country United States Media print-electronic
Document type Journal Article, Research Support, Non-U.S. Gov't
- MeSH
- Adjuvants, Immunologic administration & dosage MeSH
- Survival Analysis MeSH
- Administration, Inhalation MeSH
- Bacillus immunology MeSH
- Immunization methods MeSH
- Vaccines, Inactivated administration & dosage immunology MeSH
- Orthomyxoviridae Infections immunology prevention & control MeSH
- Mice, Inbred BALB C MeSH
- Mice MeSH
- Influenza Vaccines administration & dosage immunology MeSH
- Influenza B virus immunology MeSH
- Cross Protection MeSH
- Animals MeSH
- Check Tag
- Mice MeSH
- Female MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- Adjuvants, Immunologic MeSH
- Vaccines, Inactivated MeSH
- Influenza Vaccines MeSH
Intratracheal immunization of mice with inactivated influenza B virus and delipidated Bacillus firmus as adjuvant increases protection of mice against infection with the homologous virus strain and induces cross-protection: mice immunized by influenza virus B/Yamanashi 166/98 were protected even against phylogenetically distant virus drift variant B/Lee/40 lethal for mice.
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