Biodegradable stents for the treatment of benign stenoses of the small and large intestines
Jazyk angličtina Země Německo Médium print-electronic
Typ dokumentu časopisecké články, práce podpořená grantem
PubMed
21623562
DOI
10.1055/s-0030-1256405
Knihovny.cz E-zdroje
- MeSH
- Crohnova nemoc komplikace MeSH
- dospělí MeSH
- kolon patologie MeSH
- lidé středního věku MeSH
- lidé MeSH
- následné studie MeSH
- nemoci střev etiologie terapie MeSH
- prospektivní studie MeSH
- selhání protézy MeSH
- stenóza etiologie terapie MeSH
- stenty * MeSH
- tenké střevo patologie MeSH
- vstřebatelné implantáty * MeSH
- výsledek terapie MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
Biodegradable stents, which are made of various synthetic polymers, such as polylactide or polyglycolide, or co-polymers, such as polydioxanone, can be used for the treatment of benign refractory stenoses of the gastrointestinal tract. Here we report 11 patients (median age 41) with stenosing Crohn's disease of the small and/or large intestine. Endoscopic insertion of a biodegradable stent was successful at the first attempt in all patients except one. Subsequent follow-up was for a mean of 16 months, median 17 months, range 12-29 months. Early stent migration (between 2 days and 8 weeks) was seen in three patients. Mucosal overgrowth (epithelial hyperplasia) was not observed in any of the patients during the follow-up period. The high rate of early stent migration might be solved by appropriate tailoring and further improvements in the design of the biodegradable stents. Proof of long-term efficacy and safety requires further studies.
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