Biodegradable polymers are promising materials for use in medical applications such as stents. Their properties are comparable to commercially available resistant metal and polymeric stents, which have several major problems, such as stent migration and stent clogging due to microbial biofilm. Consequently, conventional stents have to be removed operatively from the patient's body, which presents a number of complications and can also endanger the patient's life. Biodegradable stents disintegrate into basic substances that decompose in the human body, and no surgery is required. This review focuses on the specific use of stents in the human body, the problems of microbial biofilm, and possibilities of preventing microbial growth by modifying polymers with antimicrobial agents.

Center of Advanced Innovation Technologies VŠB Technical University of Ostrava 17 listopadu 15 708 00 Ostrava Poruba Czech Republic

Department of Biology and Ecology Faculty of Science University of Ostrava Chittussiho 10 71000 Ostrava Czech Republic

ENET Centre VŠB Technical University of Ostrava 17 listopadu 15 708 00 Ostrava Poruba Czech Republic

Faculty of Technology Tomas Bata University in Zlín Vavrečkova 275 760 01 Zlín Czech Republic

Institute of Polymer Science and Technology Juan de la Cierva 3 28001 Madrid Spain

Nanotechnology Centre VŠB Technical University of Ostrava 17 listopadu 15 708 00 Ostrava Poruba Czech Republic

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