Identification of pavinane alkaloids in the genera Argemone and Eschscholzia by GC-MS
Language English Country United States Media print
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
23156990
Knihovny.cz E-resources
- MeSH
- Alkaloids analysis isolation & purification MeSH
- Argemone chemistry MeSH
- Benzylisoquinolines analysis isolation & purification MeSH
- Eschscholzia chemistry MeSH
- Plant Leaves chemistry MeSH
- Gas Chromatography-Mass Spectrometry MeSH
- Reference Standards MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- Alkaloids MeSH
- Benzylisoquinolines MeSH
The genera Eschscholtzia and Argemone (Papaveraceae) represent a rich source of pavinane alkaloids, the identification of which in alkaloid extracts is generally problematic without standards. The alkaloid extracts of three Argemone and four Eschscholtzia species were analyzed using GC-MS. The alkaloids were identified based on comparison of their mass spectra with commercial libraries, with reported data in the literature and with spectra of reference compounds. A total of 23 alkaloids of six structural types (pavinane, protopine, benzylisoquinoline, benzophenanthridine, aporphine and protoberberine) were identified. The fragmentation pathway of pavinane alkaloids was used for their identification. O-Methylneocaryachine has been reported for the first time from a natural sources and the alkaloid pattern of Eschscholzia pulchella has been analyzed and described for the first time.
