The practicality was examined of performing a cumulative dietary exposure assessment according to the requirements of the EFSA guidance on probabilistic modelling. For this the acute and chronic cumulative exposure to triazole pesticides was estimated using national food consumption and monitoring data of eight European countries. Both the acute and chronic cumulative dietary exposures were calculated according to two model runs (optimistic and pessimistic) as recommended in the EFSA guidance. The exposures obtained with these model runs differed substantially for all countries, with the highest exposures obtained with the pessimistic model run. In this model run, animal commodities including cattle milk and different meat types, entered in the exposure calculations at the level of the maximum residue limit (MRL), contributed most to the exposure. We conclude that application of the optimistic model run on a routine basis for cumulative assessments is feasible. The pessimistic model run is laborious and the exposure results could be too far from reality. More experience with this approach is needed to stimulate the discussion of the feasibility of all the requirements, especially the inclusion of MRLs of animal commodities which seem to result in unrealistic conclusions regarding their contribution to the dietary exposure.

Biometris Wageningen University and Research Centre P O Box 16 6700 AA Wageningen The Netherlands

Consiglio per la Ricerca e la sperimentazione in Agricoltura Centro di ricerca per gli alimenti e la NUTrizione via Ardeatina 546 00178 Rome Italy

French Agency for Food Environmental and Occupational Health and Safety Risk Assessment Department 27 31 avenue du Général Leclerc 94701 Maisons Alfort Cedex France

Health and Safety Executive Chemicals Regulation Directorate Mallard House Kings Pool 3 Peasholme Green York YO1 7PX UK

ICPS International Centre for Pesticides and Health Risk Prevention AO Luigi Sacco Polo Universitario Padiglione 17 Via G B Grassi 74 Milan Hospital Milan Italy

Ministry of Health State General Laboratory 44 Kimonos Street 1451 Nicosia Cyprus

National Food Agency Risk Benefit Assessment Department Box 622 751 26 Uppsala Sweden

National Food Institute Technical University of Denmark Department of Food Chemistry Mørkhøj Bygade 19 DK 2860 Søborg Denmark

National Institute for Public Health and the Environment Box 1 NL 3720 BA Bilthoven The Netherlands

National Institute of Public Health Prague Center for Health Nutrition and Food Palackého 3a 61242 Brno Czech Republic

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