Endometriosis and cancer
Language English Country United States Media print
Document type Journal Article, Research Support, Non-U.S. Gov't, Review
PubMed
25482486
DOI
10.2217/whe.14.43
Knihovny.cz E-resources
- Keywords
- cancer, endometriosis, markers, ovarian cancer, stem cells,
- MeSH
- Endometriosis complications physiopathology MeSH
- Stem Cells physiology MeSH
- Humans MeSH
- Ovarian Neoplasms etiology MeSH
- Check Tag
- Humans MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Review MeSH
Endometriosis is manifested by the presence of both endometrial glandular and stromal cells outside the uterine cavity. It is characterized by ectopic implantation of endometrial cells with elevated proliferation and migration. Endometriosis is the leading cause of morbidity among premenopausal women and the complex pathogenesis of this disease remains controversial despite extensive research. This rather complex disease has a significant impact on quality of life of many women as none of the current treatments represent a cure. Based on the current knowledge, one can conclude that the histological and genetic alterations in endometriosis might explain why and how endometriosis can change into several types of cancer. However, the exact mechanisms of this conversion are still not fully established.
References provided by Crossref.org
Endometrial cancer-is our knowledge changing?
Endometriosis and risk of ovarian cancer: what do we know?
