Characterization of microbial siderophores by mass spectrometry
Language English Country United States Media print-electronic
Document type Journal Article, Research Support, Non-U.S. Gov't, Review
PubMed
25980644
DOI
10.1002/mas.21461
Knihovny.cz E-resources
- Keywords
- biomarkers, dereplication, iron, mass spectrometry, siderophores,
- MeSH
- Drug Resistance, Microbial MeSH
- Biodegradation, Environmental MeSH
- Chelating Agents pharmacology MeSH
- Mass Spectrometry methods MeSH
- Microbial Sensitivity Tests MeSH
- Secondary Metabolism MeSH
- Siderophores analysis chemistry metabolism pharmacology MeSH
- Spectrophotometry, Atomic methods MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Review MeSH
- Names of Substances
- Chelating Agents MeSH
- Siderophores MeSH
Siderophores play important roles in microbial iron piracy, and are applied as infectious disease biomarkers and novel pharmaceutical drugs. Inductively coupled plasma and molecular mass spectrometry (ICP-MS) combined with high resolution separations allow characterization of siderophores in complex samples taking advantages of mass defect data filtering, tandem mass spectrometry, and iron-containing compound quantitation. The enrichment approaches used in siderophore analysis and current ICP-MS technologies are reviewed. The recent tools for fast dereplication of secondary metabolites and their databases are reported. This review on siderophores is concluded with their recent medical, biochemical, geochemical, and agricultural applications in mass spectrometry context.
Institute of Microbiology AS CR v v i Videnska 1083 CZ 142 20 Prague 4 Czech Republic
Special Centre for Molecular Medicine Jawaharlal Nehru University New Delhi 110067 India
References provided by Crossref.org
Rhizoferrin Glycosylation in Rhizopus microsporus
Isolation and identification of siderophores produced by cyanobacteria
Non-invasive and invasive diagnoses of aspergillosis in a rat model by mass spectrometry
