Patients with chronic rhinosinusitis and simultaneous bronchial asthma suffer from significant extraesophageal reflux
Jazyk angličtina Země Spojené státy americké Médium print-electronic
Typ dokumentu klinické zkoušky, časopisecké články, práce podpořená grantem
PubMed
26046448
DOI
10.1002/alr.21560
Knihovny.cz E-zdroje
- Klíčová slova
- antireflux therapy, bronchial asthma, chronic rhinosinusitis, extraesophageal reflux, oropharyngeal pH monitoring,
- MeSH
- bronchiální astma epidemiologie MeSH
- chronická nemoc MeSH
- dospělí MeSH
- gastroezofageální reflux epidemiologie MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladý dospělý MeSH
- nosní polypy epidemiologie MeSH
- prevalence MeSH
- progrese nemoci MeSH
- rýma epidemiologie MeSH
- sinusitida epidemiologie MeSH
- stupeň závažnosti nemoci MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladý dospělý MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- klinické zkoušky MeSH
- práce podpořená grantem MeSH
- Geografické názvy
- Kanada MeSH
BACKGROUND: The aim of this study was to determine the severity of extraesophageal reflux (EER) in patients with various degrees of chronic rhinosinusitis (CRS), and particularly in patients with simultaneous bronchial asthma. METHODS: Patients with different severity of CRS were invited to participate in the study. Group I consisted of patients with CRS without nasal polyps or bronchial asthma; group II consisted of patients with CRS with nasal polyps but without bronchial asthma; group III consisted of patients with CRS with nasal polyps and bronchial asthma. The age, gender, Reflux Symptom Index, severity of EER evaluated using the Restech system, and number of previous functional endoscopic sinus surgeries (FESSs) were compared between groups. RESULTS: A total of 90 patients (30 in each group) were recruited for the study. Pathological EER was significantly often present in group III when compared with group I and group II in all parameters analyzed (RYAN score, number of EER episodes, total percentage of time below pH 5.5). Furthermore, patients from group III had undergone more surgeries in the past. CONCLUSION: Patients with CRS with nasal polyps and simultaneous bronchial asthma suffer from significant EER. Antireflux therapy can be recommended for these patients. However, the effect has to be confirmed in further studies.
Department of Gastroenterology Vítkovice Hospital Ostrava Czech Republic
Faculty of Medicine University of Ostrava Ostrava Czech Republic
Citace poskytuje Crossref.org
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Diagnostic Value of the PeptestTM in Detecting Laryngopharyngeal Reflux
ClinicalTrials.gov
NCT01819454
