Patients with chronic rhinosinusitis and simultaneous bronchial asthma suffer from significant extraesophageal reflux
Language English Country United States Media print-electronic
Document type Clinical Trial, Journal Article, Research Support, Non-U.S. Gov't
PubMed
26046448
DOI
10.1002/alr.21560
Knihovny.cz E-resources
- Keywords
- antireflux therapy, bronchial asthma, chronic rhinosinusitis, extraesophageal reflux, oropharyngeal pH monitoring,
- MeSH
- Asthma epidemiology MeSH
- Chronic Disease MeSH
- Adult MeSH
- Gastroesophageal Reflux epidemiology MeSH
- Middle Aged MeSH
- Humans MeSH
- Young Adult MeSH
- Nasal Polyps epidemiology MeSH
- Prevalence MeSH
- Disease Progression MeSH
- Rhinitis epidemiology MeSH
- Sinusitis epidemiology MeSH
- Severity of Illness Index MeSH
- Check Tag
- Adult MeSH
- Middle Aged MeSH
- Humans MeSH
- Young Adult MeSH
- Male MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Clinical Trial MeSH
- Research Support, Non-U.S. Gov't MeSH
- Geographicals
- Canada MeSH
BACKGROUND: The aim of this study was to determine the severity of extraesophageal reflux (EER) in patients with various degrees of chronic rhinosinusitis (CRS), and particularly in patients with simultaneous bronchial asthma. METHODS: Patients with different severity of CRS were invited to participate in the study. Group I consisted of patients with CRS without nasal polyps or bronchial asthma; group II consisted of patients with CRS with nasal polyps but without bronchial asthma; group III consisted of patients with CRS with nasal polyps and bronchial asthma. The age, gender, Reflux Symptom Index, severity of EER evaluated using the Restech system, and number of previous functional endoscopic sinus surgeries (FESSs) were compared between groups. RESULTS: A total of 90 patients (30 in each group) were recruited for the study. Pathological EER was significantly often present in group III when compared with group I and group II in all parameters analyzed (RYAN score, number of EER episodes, total percentage of time below pH 5.5). Furthermore, patients from group III had undergone more surgeries in the past. CONCLUSION: Patients with CRS with nasal polyps and simultaneous bronchial asthma suffer from significant EER. Antireflux therapy can be recommended for these patients. However, the effect has to be confirmed in further studies.
Department of Gastroenterology Vítkovice Hospital Ostrava Czech Republic
Faculty of Medicine University of Ostrava Ostrava Czech Republic
References provided by Crossref.org
Association Between Inferior Turbinate Hypertrophy and Extraesophageal Reflux
Diagnostic Value of the PeptestTM in Detecting Laryngopharyngeal Reflux
ClinicalTrials.gov
NCT01819454
