Acute heart failure and cardiogenic shock: a multidisciplinary practical guidance

. 2016 Feb ; 42 (2) : 147-63. [epub] 20150914

Jazyk angličtina Země Spojené státy americké Médium print-electronic

Typ dokumentu časopisecké články, práce podpořená grantem, přehledy

Perzistentní odkaz   https://www.medvik.cz/link/pmid26370690
Odkazy

PubMed 26370690
DOI 10.1007/s00134-015-4041-5
PII: 10.1007/s00134-015-4041-5
Knihovny.cz E-zdroje

PURPOSE: Acute heart failure (AHF) causes high burden of mortality, morbidity, and repeated hospitalizations worldwide. This guidance paper describes the tailored treatment approaches of different clinical scenarios of AHF and CS, focusing on the needs of professionals working in intensive care settings. RESULTS: Tissue congestion and hypoperfusion are the two leading mechanisms of end-organ injury and dysfunction, which are associated with worse outcome in AHF. Diagnosis of AHF is based on clinical assessment, measurement of natriuretic peptides, and imaging modalities. Simultaneously, emphasis should be given in rapidly identifying the underlying trigger of AHF and assessing severity of AHF, as well as in recognizing end-organ injuries. Early initiation of effective treatment is associated with superior outcomes. Oxygen, diuretics, and vasodilators are the key therapies for the initial treatment of AHF. In case of respiratory distress, non-invasive ventilation with pressure support should be promptly started. In patients with severe forms of AHF with cardiogenic shock (CS), inotropes are recommended to achieve hemodynamic stability and restore tissue perfusion. In refractory CS, when hemodynamic stabilization is not achieved, the use of mechanical support with assist devices should be considered early, before the development of irreversible end-organ injuries. CONCLUSION: A multidisciplinary approach along the entire patient journey from pre-hospital care to hospital discharge is needed to ensure early recognition, risk stratification, and the benefit of available therapies. Medical management should be planned according to the underlying mechanisms of various clinical scenarios of AHF.

Anaesthesia and Intensive Care St George's Hospital and Medical School London SW17 0QT UK

Cardiology Unit Department of Medicine University of Abuja Teaching Hospital Gwagwalada Abuja Nigeria

Christchurch Cardioendocrine Research Group Christchurch Hospital Christchurch New Zealand

Department of Anesthesia and Critical Care Hôpital Lariboisière APHP Paris France

Department of Cardiology and Cardiovascular Research Institute Basel University Hospital Basel Basel Switzerland

Department of Cardiology Cumhuriyet University School of Medicine Sivas Turkey

Department of Cardiology Hôpital Lariboisiere APHP Paris France

Department of Cardiology Kaunas University of Medicine Kaunas Lithuania

Department of Cardiovascular Disease International Clinical Research Center University Hospital Brno Brno Czech Republic

Department of Emergency and Intensive Care Medicine Paracelsus Medical University Nuremberg Germany

Department of Emergency Medicine Baylor College of Medicine Boston MA USA

Department of Intensive Care Medicine Consorci Sanitari Integral University of Barcelona Barcelona Spain

Department of Internal Medicine Seoul National University Bundang Hospital Seongnam Korea

Department of Medical Sciences and Translational Medicine University of Rome Sapienza Sant'Andrea Hospital Rome Italy

Division of Cardiology Massachusetts General Hospital Boston MA USA

Emergency Department and Research Unit UR06SP21 Fattouma Bourguiba University Hospital Monastir Tunisia

Faculty of Health Sciences Hatter Institute for Cardiovascular Research in Africa and IIDMM University of Cape Town Cape Town South Africa

Heart and Lung Center Helsinki University Central Hospital Helsinki Finland

Internal Medicine Cardiology and Intensive Care Unit Nippon Medical School Musashi Kosugi Hospital Kawasaki Japan

Medical Clinic 2 University Heart Centre Luebeck University Hospital Schleswig Holstein Lübeck Germany

U 942 Inserm Paris France

University Paris Diderot Sorbonne Paris Cité Paris France

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