T1 mapping of the ischemic myocardium: Review of potential clinical use
Language English Country Ireland Media print-electronic
Document type Journal Article, Review
PubMed
27105590
DOI
10.1016/j.ejrad.2016.04.010
PII: S0720-048X(16)30121-8
Knihovny.cz E-resources
- Keywords
- Cardiac magnetic resonance, Ischemic heart disease, T1 mapping,
- MeSH
- Myocardial Ischemia diagnostic imaging pathology MeSH
- Humans MeSH
- Magnetic Resonance Imaging methods MeSH
- Myocardium pathology MeSH
- Reproducibility of Results MeSH
- Heart diagnostic imaging MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
- Review MeSH
Cardiac magnetic resonance imaging (CMR) is an indispensable part of the diagnostic algorithm in cardiology. CMR has become a gold standard in various disorders; moreover, it is well established also as a surrogate end-point in experimental and clinical studies. Particularly, the ability to directly display myocardial injury is a unique feature in comparison with other methods. The mapping of magnetic relaxation properties (T1, T2 and T2* relaxation times) are still relatively new techniques, but promising to improve the robustness of CMR and add new appropriate indications. The high potential of T1 mapping in the diagnostic of myocardial ischemic involvement has been highlighted in several experimental and clinical studies, but the use in clinical routine was limited due to the shortcomings in scanning and image evaluation. However, the quantitative technique of T1 mapping is now commercially available and its simple use, good reproducibility and limited subjectivity allow its incorporation into routine CMR protocols. This review article is aimed to summarise existing results and clinical experience with T1 mapping in patients with ischemic cardiac disease.
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