Trace elements have beneficial, as well as detrimental effects on bone homeostasis
Language English Country Czech Republic Media print-electronic
Document type Journal Article, Review
PubMed
28248532
DOI
10.33549/physiolres.933454
PII: 933454
Knihovny.cz E-resources
- MeSH
- Homeostasis drug effects physiology MeSH
- Magnesium administration & dosage metabolism MeSH
- Cadmium adverse effects metabolism MeSH
- Bone Density drug effects physiology MeSH
- Humans MeSH
- Lead adverse effects metabolism MeSH
- Trace Elements administration & dosage adverse effects metabolism MeSH
- Iron administration & dosage metabolism MeSH
- Animals MeSH
- Check Tag
- Humans MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Review MeSH
- Names of Substances
- Magnesium MeSH
- Cadmium MeSH
- Lead MeSH
- Trace Elements MeSH
- Iron MeSH
The protective role of nutrition factors such as calcium, vitamin D and vitamin K for the integrity of the skeleton is well understood. In addition, integrity of the skeleton is positively influenced by certain trace elements (e.g. zinc, copper, manganese, magnesium, iron, selenium, boron and fluoride) and negatively by others (lead, cadmium, cobalt). Deficiency or excess of these elements influence bone mass and bone quality in adulthood as well as in childhood and adolescence. However, some protective elements may become toxic under certain conditions, depending on dosage (serum concentration), duration of treatment and interactions among individual elements. We review the beneficial and toxic effects of key elements on bone homeostasis.
References provided by Crossref.org
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