C/EBPγ is dispensable for steady-state and emergency granulopoiesis
Language English Country Italy Media print-electronic
Document type Letter, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't
Grant support
P01 CA066996
NCI NIH HHS - United States
P01 HL131477
NHLBI NIH HHS - United States
P30 CA013148
NCI NIH HHS - United States
R35 CA197697
NCI NIH HHS - United States
PubMed
29567783
PubMed Central
PMC6068020
DOI
10.3324/haematol.2017.173781
PII: haematol.2017.173781
Knihovny.cz E-resources
- MeSH
- Cell Lineage MeSH
- Granulocytes cytology MeSH
- Hematopoiesis * MeSH
- Mice, Knockout MeSH
- Mice MeSH
- CCAAT-Enhancer-Binding Proteins deficiency physiology MeSH
- Transcription Factors MeSH
- Animals MeSH
- Check Tag
- Mice MeSH
- Animals MeSH
- Publication type
- Letter MeSH
- Research Support, Non-U.S. Gov't MeSH
- Research Support, N.I.H., Extramural MeSH
- Names of Substances
- CCAAT-enhancer-binding protein-gamma MeSH Browser
- CCAAT-Enhancer-Binding Proteins MeSH
- Transcription Factors MeSH
Cancer Science Institute National University of Singapore Singapore
CLIP Childhood Leukaemia Investigation Prague Czech Republic
Department of Cell Biology Charles University Faculty of Science Prague Czech Republic
Department of Systems Biology University of Texas MD Anderson Cancer Center Houston TX USA
Harvard Stem Cell Institute Harvard Medical School Boston MA USA
Hematology Oncology Department University of Alabama at Birmingham AL USA
Institute of Molecular Genetics of the Czech Academy of Sciences Prague Czech Republic
See more in PubMed
Bugl S, Wirths S, Radsak MP, et al. Steady-state neutrophil homeostasis is dependent on TLR4/TRIF signaling. Blood. 2013;121(5):723–733. PubMed
Manz MG, Boettcher S. Emergency granulopoiesis. Nat Rev Immunol. 2014;14(5):302–314. PubMed
Hirai H, Zhang P, Dayaram T, et al. C/EBPbeta is required for ‘emergency’ granulopoiesis. Nat Immunol. 2006;7(7):732–739. PubMed
Satake S, Hirai H, Hayashi Y, et al. C/EBPbeta is involved in the amplification of early granulocyte precursors during candidemia-induced “emergency” granulopoiesis. J Immunol. 2012;189(9):4546–4555. PubMed
Zhang DE, Zhang P, Wang ND, Hetherington CJ, Darlington GJ, Tenen DG. Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein alpha-deficient mice. Proc Natl Acad Sci U S A. 1997;94(2):569–574. PubMed PMC
Alberich-Jorda M, Wouters B, Balastik M, et al. C/EBPgamma dereg ulation results in differentiation arrest in acute myeloid leukemia. J Clin Invest. 2012;122(12):4490–4504. PubMed PMC
Roman C, Platero JS, Shuman J, Calame K. Ig/EBP-1: a ubiquitously expressed immunoglobulin enhancer binding protein that is similar to C/EBP and heterodimerizes with C/EBP. Genes Dev. 1990;4(8):1404–1415. PubMed
Huggins CJ, Malik R, Lee S, et al. C/EBPgamma suppresses senescence and inflammatory gene expression by heterodimerizing with C/EBPbeta. Mol Cell Biol. 2013;33(16):3242–3258. PubMed PMC
Huggins CJ, Mayekar MK, Martin N, et al. C/EBPgamma as a critical regulator of cellular stress response networks through heterodimerization with ATF4. Mol Cell Biol. 2015;36(5):693–713. PubMed PMC
Boettcher S, Gerosa RC, Radpour R, et al. Endothelial cells translate pathogen signals into G-CSF-driven emergency granulopoiesis. Blood. 2014;124(9):1393–1403. PubMed PMC
Boettcher S, Ziegler P, Schmid MA, et al. Cutting edge: LPS-induced emergency myelopoiesis depends on TLR4-expressing non-hematopoietic cells. J Immunol. 2012;188(12):5824–5828. PubMed
Poltorak A, He X, Smirnova I, et al. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science. 1998;282(5396):2085–2088. PubMed
Lieschke GJ, Grail D, Hodgson G, et al. Mice lacking granulocyte colony-stimulating factor have chronic neutropenia, granulocyte and macrophage progenitor cell deficiency, and impaired neutrophil mobilization. Blood. 1994;84(6):1737–1746. PubMed
Kaisho T, Tsutsui H, Tanaka T, et al. Impairment of natural killer cytotoxic activity and interferon gamma production in CCAAT/enhancer binding protein gamma-deficient mice. J Exp Med. 1999;190(11):1573–1582. PubMed PMC
Bardet-Biedl Syndrome ciliopathy is linked to altered hematopoiesis and dysregulated self-tolerance