Serious chronic disease of the cervical spine and trauma in a young female from the middle ages (Czech Republic)
Language English Country Netherlands Media print-electronic
Document type Historical Article, Journal Article, Research Support, Non-U.S. Gov't
PubMed
30497062
DOI
10.1016/j.ijpp.2018.11.004
PII: S1879-9817(17)30155-9
Knihovny.cz E-resources
- Keywords
- Early middle ages, Fracture, Mycosis, Osteomyelitis, Palaeopathology, Pohansko, Trauma, Tuberculosis,
- MeSH
- Chronic Disease MeSH
- History, Medieval MeSH
- Fractures, Bone history pathology MeSH
- Cervical Vertebrae pathology MeSH
- Neck pathology MeSH
- Humans MeSH
- Spinal Injuries history MeSH
- Wounds and Injuries diagnosis history pathology MeSH
- Tuberculosis diagnosis history pathology MeSH
- Check Tag
- History, Medieval MeSH
- Humans MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Historical Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Geographicals
- Czech Republic MeSH
The skeletal remains of the young female (20-24 years) from Grave JP/106, discovered in the Southern Suburb of the Břeclav - Pohansko Stronghold (Early Middle Ages, 9th century-beginning of the 10th century, present day Czech Republic) display several noteworthy pathologies. The first is deformation of the mandible, which was most probably caused by a fracture of the ramus in combination with a subcondylar fracture. The spine of this young woman also exhibits a probable traumatic injury of the cervical spine in combination with a slowly growing structure situated inside the spinal canal, which caused deformation centered upon C7. The cervical and thoracic spine together with internal surfaces of several ribs exhibit infectious changes of advanced stage, in all likelihood of tuberculous origin, but osteomyelitis cannot be excluded. Histological analysis of the new bone formation in the ribs confirmed infectious origin, as does Micro CT of C5 and C6. Analyses conducted by two different departments with different methods (PCR amplification of 123 bp long section from IS6110 and Next Generation shotgun sequencing) failed to identify DNA of Mycobacterium tuberculosis from the first rib.
Centre for GeoGenetics Natural History Museum Øster Voldgade 5 7 1350 Copenhagen Denmark
Independent Scientist Brno Czech Republic
Thuringia State Service for Cultural Heritage and Archaeology Weimar Germany
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