Inhibitors of Cholinesterases in Pharmacology: the Current Trends
Language English Country Netherlands Media print
Document type Journal Article, Review
PubMed
31656151
DOI
10.2174/1389557519666191018170908
PII: MRMC-EPUB-101634
Knihovny.cz E-resources
- Keywords
- Acetylcholinesterase, Alzheimer disease, butyrylcholinesterase, cholinergic anti-inflammatory pathway, donepezil, galantamine, huperzine, myasthenia gravis, nerve agents, rivastigmine,
- MeSH
- Alzheimer Disease drug therapy pathology MeSH
- Anti-Inflammatory Agents chemistry pharmacology therapeutic use MeSH
- Autoimmune Diseases drug therapy pathology MeSH
- Cholinesterase Inhibitors chemistry metabolism pharmacology therapeutic use MeSH
- Cholinesterases chemistry metabolism MeSH
- Insecticides chemistry MeSH
- Humans MeSH
- Nerve Agents chemistry metabolism MeSH
- Protein Binding MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
- Review MeSH
- Names of Substances
- Anti-Inflammatory Agents MeSH
- Cholinesterase Inhibitors MeSH
- Cholinesterases MeSH
- Insecticides MeSH
- Nerve Agents MeSH
Inhibitors of cholinesterases are a wide group of low molecular weight compounds with a significant role in the current pharmacology. Besides the pharmacological importance, they are also known as toxic compounds like military nerve agents. In the pharmacology, drugs for Alzheimer disease, myasthenia gravis and prophylaxis of poisoning by nerve agents can be mentioned as the relevant applications. Besides this, anti-inflammation and antiphrastic drugs are other pharmacological applications of these inhibitors. This review is focused on a survey of cholinesterase inhibitors with known or expected pharmacological impact and indications of their use. Recent literature with comments is provided here as well.
References provided by Crossref.org
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