Inhibitors of Cholinesterases in Pharmacology: the Current Trends
Jazyk angličtina Země Nizozemsko Médium print
Typ dokumentu časopisecké články, přehledy
PubMed
31656151
DOI
10.2174/1389557519666191018170908
PII: MRMC-EPUB-101634
Knihovny.cz E-zdroje
- Klíčová slova
- Acetylcholinesterase, Alzheimer disease, butyrylcholinesterase, cholinergic anti-inflammatory pathway, donepezil, galantamine, huperzine, myasthenia gravis, nerve agents, rivastigmine,
- MeSH
- Alzheimerova nemoc farmakoterapie patologie MeSH
- antiflogistika chemie farmakologie terapeutické užití MeSH
- autoimunitní nemoci farmakoterapie patologie MeSH
- cholinesterasové inhibitory chemie metabolismus farmakologie terapeutické užití MeSH
- cholinesterasy chemie metabolismus MeSH
- insekticidy chemie MeSH
- lidé MeSH
- nervová bojová látka chemie metabolismus MeSH
- vazba proteinů MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- přehledy MeSH
- Názvy látek
- antiflogistika MeSH
- cholinesterasové inhibitory MeSH
- cholinesterasy MeSH
- insekticidy MeSH
- nervová bojová látka MeSH
Inhibitors of cholinesterases are a wide group of low molecular weight compounds with a significant role in the current pharmacology. Besides the pharmacological importance, they are also known as toxic compounds like military nerve agents. In the pharmacology, drugs for Alzheimer disease, myasthenia gravis and prophylaxis of poisoning by nerve agents can be mentioned as the relevant applications. Besides this, anti-inflammation and antiphrastic drugs are other pharmacological applications of these inhibitors. This review is focused on a survey of cholinesterase inhibitors with known or expected pharmacological impact and indications of their use. Recent literature with comments is provided here as well.
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