Plants as non-mobile organisms constantly integrate varying environmental signals to flexibly adapt their growth and development. Local fluctuations in water and nutrient availability, sudden changes in temperature or other abiotic and biotic stresses can trigger changes in the growth of plant organs. Multiple mutually interconnected hormonal signaling cascades act as essential endogenous translators of these exogenous signals in the adaptive responses of plants. Although the molecular backbones of hormone transduction pathways have been identified, the mechanisms underlying their interactions are largely unknown. Here, using genome wide transcriptome profiling we identify an auxin and cytokinin cross-talk component; SYNERGISTIC ON AUXIN AND CYTOKININ 1 (SYAC1), whose expression in roots is strictly dependent on both of these hormonal pathways. We show that SYAC1 is a regulator of secretory pathway, whose enhanced activity interferes with deposition of cell wall components and can fine-tune organ growth and sensitivity to soil pathogens.

Bioresources Unit Center for Health and Bioresources AIT Austrian Institute of Technology Tulln Austria

Departamento de Biología de Organismos y Sistemas Universidad de Oviedo Oviedo Spain

Department of Cellular Biochemistry Institute for Biochemistry and Biotechnology Martin Luther University Halle Wittenberg Halle Germany

Department of Chemistry Umeå University Linnaeus väg 6 SE 901 87 Umeå Sweden

Department of Plant Biotechnology and Bioinformatics Ghent University Ghent Belgium

Institut für Botanik Technische Universität Dresden Dresden Germany

Institut Jean Pierre Bourgin INRAE AgroParisTech Université Paris Saclay 78000 Versailles France

Institute of Biophysics The Czech Academy of Sciences Královopolská 135 61265 Brno Czech Republic

Institute of Science and Technology Klosterneuburg Austria

Mendel Centre for Plant Genomics and Proteomics CEITEC Masaryk University Brno Czech Republic

Molecular Biology and Biochemistry Gottfried Schatz Research Center Medical University of Graz Neue Stiftingtalstraße 6 6 8010 Graz Austria

Umeå Plant Science Centre Department of Forest Genetics and Plant Physiology Swedish University of Agricultural Sciences S 901 83 Umeå Sweden

Unité 'Ecologie et Dynamique des Systèmes Anthropisés' Université du Picardie Jules Verne UFR des Sciences Amiens France

VIB Center for Plant Systems Biology Ghent Belgium

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