Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused the COVID-19 pandemic that has been spreading around the world since December 2019. More than 10 million affected cases and more than half a million deaths have been reported so far, while no vaccine is yet available as a treatment. Considering the global healthcare urgency, several techniques, including whole genome sequencing and computed tomography imaging have been employed for diagnosing infected people. Considerable efforts are also directed at detecting and preventing different modes of community transmission. Among them is the rapid detection of virus presence on different surfaces with which people may come in contact. Detection based on non-contact optical techniques is very helpful in managing the spread of the virus, and to aid in the disinfection of surfaces. Nanomaterial-based methods are proven suitable for rapid detection. Given the immense need for science led innovative solutions, this manuscript critically reviews recent literature to specifically illustrate nano-engineered effective and rapid solutions. In addition, all the different techniques are critically analyzed, compared, and contrasted to identify the most promising methods. Moreover, promising research ideas for high accuracy of detection in trace concentrations, via color change and light-sensitive nanostructures, to assist fingerprint techniques (to identify the virus at the contact surface of the gas and solid phase) are also presented.

Biomaterial Group Department of Biomedical Engineering Amirkabir University of Technology Tehran 15875 4413 Iran

Biomaterials Group School of Materials Science and Engineering Iran University of Science and Technology Tehran 16844 Iran

Cellular and Molecular Biology Research Center Shahid Beheshti University of Medical Sciences Tehran 19857 17443 Iran

Center for Nanofibers and Nanotechnology National University of Singapore Singapore 117576 Singapore

Department of Chemistry Sharif University of Technology Tehran 11155 3516 Iran

Department of Materials Science and Engineering Research Institute of Advanced Materials Seoul National University Seoul 08826 Korea

Department of Materials Science and Engineering Sharif University of Technology Tehran 11155 9466 Iran

Department of Pharmaceutical Nanotechnology Faculty of Pharmacy Tehran University of Medical Sciences Tehran 14155 6451 Iran

Nanotechnology Research Center Faculty of Pharmacy Tehran University of Medical Sciences Tehran 14155 6451 Iran

Regional Center of Advanced Technologies and Materials Palacky University Šlechtitelů 27 78371 Olomouc Czech Republic

Student Research Committee Department of Medical Biotechnology School of Advanced Technologies in Medicine Shahid Beheshti University of Medical Sciences Tehran 19857 17443 Iran

Universal Scientific Education and Research Network Tehran 15875 4413 Iran

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